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A catechol-O-methyltransferase that is essential for auditory function in mice and humans.
Du X, Schwander M, Moresco EM, Viviani P, Haller C, Hildebrand MS, Pak K, Tarantino L, Roberts A, Richardson H, Koob G, Najmabadi H, Ryan AF, Smith RJ, Müller U, Beutler B. Du X, et al. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14609-14. doi: 10.1073/pnas.0807219105. Epub 2008 Sep 15. Proc Natl Acad Sci U S A. 2008. PMID: 18794526 Free PMC article.
Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis.
Jiang Z, Georgel P, Li C, Choe J, Crozat K, Rutschmann S, Du X, Bigby T, Mudd S, Sovath S, Wilson IA, Olson A, Beutler B. Jiang Z, et al. Among authors: du x. Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):10961-6. doi: 10.1073/pnas.0603804103. Epub 2006 Jul 10. Proc Natl Acad Sci U S A. 2006. PMID: 16832055 Free PMC article.
Precis on forward genetics in mice.
Beutler B, Du X, Xia Y. Beutler B, et al. Among authors: du x. Nat Immunol. 2007 Jul;8(7):659-64. doi: 10.1038/ni0707-659. Nat Immunol. 2007. PMID: 17579639 Review. No abstract available.
The serine protease TMPRSS6 is required to sense iron deficiency.
Du X, She E, Gelbart T, Truksa J, Lee P, Xia Y, Khovananth K, Mudd S, Mann N, Moresco EM, Beutler E, Beutler B. Du X, et al. Science. 2008 May 23;320(5879):1088-92. doi: 10.1126/science.1157121. Epub 2008 May 1. Science. 2008. PMID: 18451267 Free PMC article.
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