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Involvement of the small protein tyrosine phosphatases TC-PTP and PTP1B in signal transduction and diseases: from diabetes, obesity to cell cycle, and cancer.
Dubé N, Tremblay ML. Dubé N, et al. Biochim Biophys Acta. 2005 Dec 30;1754(1-2):108-17. doi: 10.1016/j.bbapap.2005.07.030. Epub 2005 Sep 12. Biochim Biophys Acta. 2005. PMID: 16198645 Review.
Coordinated action of protein tyrosine phosphatases in insulin signal transduction.
Cheng A, Dubé N, Gu F, Tremblay ML. Cheng A, et al. Eur J Biochem. 2002 Feb;269(4):1050-9. doi: 10.1046/j.0014-2956.2002.02756.x. Eur J Biochem. 2002. PMID: 11856336 Review.
Protein tyrosine phosphatase 1B attenuates growth hormone-mediated JAK2-STAT signaling.
Gu F, Dubé N, Kim JW, Cheng A, Ibarra-Sanchez Mde J, Tremblay ML, Boisclair YR. Gu F, et al. Mol Cell Biol. 2003 Jun;23(11):3753-62. doi: 10.1128/mcb.23.11.3753-3762.2003. Mol Cell Biol. 2003. PMID: 12748279 Free PMC article.
The role of protein tyrosine phosphatase 1B in Ras signaling.
Dubé N, Cheng A, Tremblay ML. Dubé N, et al. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1834-9. doi: 10.1073/pnas.0304242101. Epub 2004 Feb 6. Proc Natl Acad Sci U S A. 2004. PMID: 14766979 Free PMC article.
Beyond the metabolic function of PTP1B.
Dubé N, Tremblay ML. Dubé N, et al. Cell Cycle. 2004 May;3(5):550-3. Epub 2004 May 10. Cell Cycle. 2004. PMID: 15044856
Hepatic PTP-1B expression regulates the assembly and secretion of apolipoprotein B-containing lipoproteins: evidence from protein tyrosine phosphatase-1B overexpression, knockout, and RNAi studies.
Qiu W, Avramoglu RK, Dubé N, Chong TM, Naples M, Au C, Sidiropoulos KG, Lewis GF, Cohn JS, Tremblay ML, Adeli K. Qiu W, et al. Diabetes. 2004 Dec;53(12):3057-66. doi: 10.2337/diabetes.53.12.3057. Diabetes. 2004. PMID: 15561934
Substrate-trapping techniques in the identification of cellular PTP targets.
Blanchetot C, Chagnon M, Dubé N, Hallé M, Tremblay ML. Blanchetot C, et al. Methods. 2005 Jan;35(1):44-53. doi: 10.1016/j.ymeth.2004.07.007. Methods. 2005. PMID: 15588985
Protein-tyrosine phosphatase 1B deficiency protects against Fas-induced hepatic failure.
Sangwan V, Paliouras GN, Cheng A, Dubé N, Tremblay ML, Park M. Sangwan V, et al. J Biol Chem. 2006 Jan 6;281(1):221-8. doi: 10.1074/jbc.M507858200. Epub 2005 Oct 17. J Biol Chem. 2006. PMID: 16234234
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