Dubeau L - Search Results

1

Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice.

Lee AS, Brandhorst S, Rangel DF, Navarrete G, Cohen P, Longo VD, Chen J, Groshen S, Morgan TE, Dubeau L. Lee AS, et al. Among authors: dubeau l. Sci Rep. 2017 Feb 1;7:40919. doi: 10.1038/srep40919. Sci Rep. 2017. PMID: 28145503 Free PMC article.

2

Cancer-inducible transgene expression by the Grp94 promoter: spontaneous activation in tumors of various origins and cancer-associated macrophages.

Reddy RK, Dubeau L, Kleiner H, Parr T, Nichols P, Ko B, Dong D, Ko H, Mao C, DiGiovanni J, Lee AS. Reddy RK, et al. Among authors: dubeau l. Cancer Res. 2002 Dec 15;62(24):7207-12. Cancer Res. 2002. PMID: 12499260

3

Spontaneous and controllable activation of suicide gene expression driven by the stress-inducible grp78 promoter resulting in eradication of sizable human tumors.

Dong D, Dubeau L, Bading J, Nguyen K, Luna M, Yu H, Gazit-Bornstein G, Gordon EM, Gomer C, Hall FL, Gambhir SS, Lee AS. Dong D, et al. Among authors: dubeau l. Hum Gene Ther. 2004 Jun;15(6):553-61. doi: 10.1089/104303404323142006. Hum Gene Ther. 2004. PMID: 15212714

4

Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development.

Dong D, Ni M, Li J, Xiong S, Ye W, Virrey JJ, Mao C, Ye R, Wang M, Pen L, Dubeau L, Groshen S, Hofman FM, Lee AS. Dong D, et al. Among authors: dubeau l. Cancer Res. 2008 Jan 15;68(2):498-505. doi: 10.1158/0008-5472.CAN-07-2950. Cancer Res. 2008. PMID: 18199545

5

Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis.

Wang M, Ye R, Barron E, Baumeister P, Mao C, Luo S, Fu Y, Luo B, Dubeau L, Hinton DR, Lee AS. Wang M, et al. Among authors: dubeau l. Cell Death Differ. 2010 Mar;17(3):488-98. doi: 10.1038/cdd.2009.144. Epub 2009 Oct 9. Cell Death Differ. 2010. PMID: 19816510 Free PMC article.

6

Genome-scale screen for DNA methylation-based detection markers for ovarian cancer.

Campan M, Moffitt M, Houshdaran S, Shen H, Widschwendter M, Daxenbichler G, Long T, Marth C, Laird-Offringa IA, Press MF, Dubeau L, Siegmund KD, Wu AH, Groshen S, Chandavarkar U, Roman LD, Berchuck A, Pearce CL, Laird PW. Campan M, et al. Among authors: dubeau l. PLoS One. 2011;6(12):e28141. doi: 10.1371/journal.pone.0028141. Epub 2011 Dec 7. PLoS One. 2011. PMID: 22163280 Free PMC article.

7

The endoplasmic reticulum stress marker, glucose-regulated protein-78 (GRP78) in visceral adipocytes predicts endometrial cancer progression and patient survival.

Matsuo K, Gray MJ, Yang DY, Srivastava SA, Tripathi PB, Sonoda LA, Yoo EJ, Dubeau L, Lee AS, Lin YG. Matsuo K, et al. Among authors: dubeau l. Gynecol Oncol. 2013 Mar;128(3):552-9. doi: 10.1016/j.ygyno.2012.11.024. Epub 2012 Nov 28. Gynecol Oncol. 2013. PMID: 23200913 Free PMC article.

8

A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan.

Brandhorst S, Choi IY, Wei M, Cheng CW, Sedrakyan S, Navarrete G, Dubeau L, Yap LP, Park R, Vinciguerra M, Di Biase S, Mirzaei H, Mirisola MG, Childress P, Ji L, Groshen S, Penna F, Odetti P, Perin L, Conti PS, Ikeno Y, Kennedy BK, Cohen P, Morgan TE, Dorff TB, Longo VD. Brandhorst S, et al. Among authors: dubeau l. Cell Metab. 2015 Jul 7;22(1):86-99. doi: 10.1016/j.cmet.2015.05.012. Epub 2015 Jun 18. Cell Metab. 2015. PMID: 26094889 Free PMC article. Clinical Trial.

9

Glucose-regulated protein 94 deficiency induces squamous cell metaplasia and suppresses PTEN-null driven endometrial epithelial tumor development.

Shen J, Yao L, Lin YG, DeMayo FJ, Lydon JP, Dubeau L, Lee AS. Shen J, et al. Among authors: dubeau l. Oncotarget. 2016 Mar 22;7(12):14885-97. doi: 10.18632/oncotarget.7450. Oncotarget. 2016. PMID: 26910913 Free PMC article.

10

GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant Kras-driven pancreatic tumorigenesis in mice.

Shen J, Ha DP, Zhu G, Rangel DF, Kobielak A, Gill PS, Groshen S, Dubeau L, Lee AS. Shen J, et al. Among authors: dubeau l. Proc Natl Acad Sci U S A. 2017 May 16;114(20):E4020-E4029. doi: 10.1073/pnas.1616060114. Epub 2017 May 1. Proc Natl Acad Sci U S A. 2017. PMID: 28461470 Free PMC article.

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