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Alphavirus vectors for gene expression and vaccines.
Schlesinger S, Dubensky TW. Schlesinger S, et al. Curr Opin Biotechnol. 1999 Oct;10(5):434-9. doi: 10.1016/s0958-1669(99)00006-3. Curr Opin Biotechnol. 1999. PMID: 10508626 Review.
Replicon vectors derived from Sindbis virus and Semliki forest virus that establish persistent replication in host cells.
Perri S, Driver DA, Gardner JP, Sherrill S, Belli BA, Dubensky TW Jr, Polo JM. Perri S, et al. J Virol. 2000 Oct;74(20):9802-7. doi: 10.1128/jvi.74.20.9802-9807.2000. J Virol. 2000. PMID: 11000258 Free PMC article.
Sindbis virus DNA-based expression vectors: utility for in vitro and in vivo gene transfer.
Dubensky TW Jr, Driver DA, Polo JM, Belli BA, Latham EM, Ibanez CE, Chada S, Brumm D, Banks TA, Mento SJ, Jolly DJ, Chang SM. Dubensky TW Jr, et al. J Virol. 1996 Jan;70(1):508-19. doi: 10.1128/JVI.70.1.508-519.1996. J Virol. 1996. PMID: 8523564 Free PMC article.
Enhancement of tumor-specific immune response with plasmid DNA replicon vectors.
Leitner WW, Ying H, Driver DA, Dubensky TW, Restifo NP. Leitner WW, et al. Cancer Res. 2000 Jan 1;60(1):51-5. Cancer Res. 2000. PMID: 10646851 Free PMC article.
Alphavirus DNA and particle replicons for vaccines and gene therapy.
Polo JM, Gardner JP, Ji Y, Belli BA, Driver DA, Sherrill S, Perri S, Liu MA, Dubensky TW Jr. Polo JM, et al. Dev Biol (Basel). 2000;104:181-5. Dev Biol (Basel). 2000. PMID: 11713818 Review.
Stable alphavirus packaging cell lines for Sindbis virus and Semliki Forest virus-derived vectors.
Polo JM, Belli BA, Driver DA, Frolov I, Sherrill S, Hariharan MJ, Townsend K, Perri S, Mento SJ, Jolly DJ, Chang SM, Schlesinger S, Dubensky TW Jr. Polo JM, et al. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4598-603. doi: 10.1073/pnas.96.8.4598. Proc Natl Acad Sci U S A. 1999. PMID: 10200308 Free PMC article.
DNA vaccines with a kick.
Polo JM, Dubensky TW Jr. Polo JM, et al. Nat Biotechnol. 1998 Jun;16(6):517-8. doi: 10.1038/nbt0698-517. Nat Biotechnol. 1998. PMID: 9624677 No abstract available.
Killed but metabolically active vaccines.
Dubensky TW Jr, Skoble J, Lauer P, Brockstedt DG. Dubensky TW Jr, et al. Curr Opin Biotechnol. 2012 Dec;23(6):917-23. doi: 10.1016/j.copbio.2012.04.005. Epub 2012 May 18. Curr Opin Biotechnol. 2012. PMID: 22608846 Review.
Virus-based vectors for human vaccine applications.
Polo JM, Dubensky TW Jr. Polo JM, et al. Drug Discov Today. 2002 Jul 1;7(13):719-27. doi: 10.1016/s1359-6446(02)02324-3. Drug Discov Today. 2002. PMID: 12110228 Review.
An alphavirus replicon particle chimera derived from venezuelan equine encephalitis and sindbis viruses is a potent gene-based vaccine delivery vector.
Perri S, Greer CE, Thudium K, Doe B, Legg H, Liu H, Romero RE, Tang Z, Bin Q, Dubensky TW Jr, Vajdy M, Otten GR, Polo JM. Perri S, et al. J Virol. 2003 Oct;77(19):10394-403. doi: 10.1128/jvi.77.19.10394-10403.2003. J Virol. 2003. PMID: 12970424 Free PMC article.
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