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Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man.
Cavagnini F, Invitti C, Pinto M, Maraschini C, Di Landro A, Dubini A, Marelli A. Cavagnini F, et al. Acta Endocrinol (Copenh). 1980 Feb;93(2):149-54. doi: 10.1530/acta.0.0930149. Acta Endocrinol (Copenh). 1980. PMID: 7376786 Clinical Trial.
A single oral dose of 5 g gamma aminobutyric acid (GABA) was given to 19 subjects and serial venous blood samples were obtained before and 3 h after drug administration. A placebo was administered to 18 subjects who served as controls. GABA caused a significa
A single oral dose of 5 g gamma aminobutyric acid (GABA) was given to 19 subjects and serial venous blood samples were obtained befor
Effects of acute administration of zetidoline, a new antidopaminergic drug, on plasma prolactin and aldosterone levels in man.
Barbieri C, Parodi M, Bruno S, Bertassi F, Benaglia D, Moser P, Meroni R, Dubini A. Barbieri C, et al. Eur J Clin Pharmacol. 1984;26(1):29-32. doi: 10.1007/BF00546704. Eur J Clin Pharmacol. 1984. PMID: 6143669 Clinical Trial.
The neuroendocrinological effects of acute oral administration of 20 mg zetidoline, a new antipsychotic drug with antidopaminergic properties, were evaluated in 8 healthy volunteers, by a double-blind, crossover comparison with placebo. ...
The neuroendocrinological effects of acute oral administration of 20 mg zetidoline, a new antipsychotic drug with antidopaminergic pr …
Lack of growth hormone response to acute administration of dexamethasone in anorexia nervosa.
Scacchi M, Invitti C, Pincelli AI, Pandolfi C, Dubini A, Cavagnini F. Scacchi M, et al. Eur J Endocrinol. 1995 Feb;132(2):152-8. doi: 10.1530/eje.0.1320152. Eur J Endocrinol. 1995. PMID: 7858732

After dexamethasone, a significant lowering of plasma cortisol was observed in normal women (AUC 25367.0 +/- 3128.43 vs 47347.1 +/- 4456.61 nmol.l-1.min-1, after dexamethasone and saline, respectively, p < 0.05), but not in anorectic patients (AUC 77809.3 +/- 8499.92 vs

After dexamethasone, a significant lowering of plasma cortisol was observed in normal women (AUC 25367.0 +/- 3128.43 vs 47347.1 +/- 4 …
Neuroendocrine effects of chronic administration of sodium valproate in epileptic patients.
Invitti C, Danesi L, Dubini A, Cavagnini F. Invitti C, et al. Acta Endocrinol (Copenh). 1988 Jul;118(3):381-8. doi: 10.1530/acta.0.1180381. Acta Endocrinol (Copenh). 1988. PMID: 2839946
These observations point to a defective hypothalamic control of GH secretion in some epileptic patients. They also indicate that chronic administration of sodium valproate, hence activation of central gamma-aminobutyric acid system, results in a blunting of the stim …
These observations point to a defective hypothalamic control of GH secretion in some epileptic patients. They also indicate that chro …
Treatment with biosynthetic growth hormone of short thalassaemic patients with impaired growth hormone secretion.
Scacchi M, Danesi L, De Martin M, Dubini A, Forni L, Masala A, Gallisai D, Burrai C, Terzoli S, Boffa C, et al. Scacchi M, et al. Clin Endocrinol (Oxf). 1991 Oct;35(4):335-9. doi: 10.1111/j.1365-2265.1991.tb03545.x. Clin Endocrinol (Oxf). 1991. PMID: 1752061
RESULTS: During the first 6 months of therapy, a significant increase of growth velocity was observed, from a mean pretreatment value of 2.1 +/- 0.45 cm/year to a value of 4.8 +/- 0.66 cm/year (P less than 0.002). ...A significant increase in plasma le …
RESULTS: During the first 6 months of therapy, a significant increase of growth velocity was observed, from a mean pretreatmen …
Effects of gamma aminobutyric acid (GABA) and muscimol on endocrine pancreatic function in man.
Cavagnini F, Pinto M, Dubini A, Invitti C, Cappelletti G, Polli EE. Cavagnini F, et al. Metabolism. 1982 Jan;31(1):73-7. Metabolism. 1982. PMID: 7043162 Clinical Trial.
In 12 normal subjects, a single oral dose of 5 or 10 g GABA, as compared to placebo, caused a significant (p less than 0.01) and dose-dependent (p less than 0.01) increase of plasma levels of immunoreactive insulin, C peptide and glucagon, without affecting plasma g …
In 12 normal subjects, a single oral dose of 5 or 10 g GABA, as compared to placebo, caused a significant (p less than 0.01) a …
Effect of gamma-aminobutyric acid on growth hormone and prolactin secretion in man: influence of pimozide and domperidone.
Cavagnini F, Benetti G, Invitti C, Ramella G, Pinto M, Lazza M, Dubini A, Marelli A, Müller EE. Cavagnini F, et al. J Clin Endocrinol Metab. 1980 Oct;51(4):789-92. doi: 10.1210/jcem-51-4-789. J Clin Endocrinol Metab. 1980. PMID: 7419665

In 9 normal volunteers, GABA caused a significant increase of plasma GH levels (P < 0.0001 vs. GH levels in a group of 14 controls). ...These findings are consistent with the hypothesis that GABA-stimulated GH secretion is mediated via dopamine release at a

In 9 normal volunteers, GABA caused a significant increase of plasma GH levels (P < 0.0001 vs. GH levels in a group of 14 c

Prolactin secretion in obese patients.
Cavagnini F, Maraschini C, Pinto M, Dubini A. Cavagnini F, et al. Lancet. 1979 Nov 10;2(8150):1020. doi: 10.1016/s0140-6736(79)92593-5. Lancet. 1979. PMID: 91750 Clinical Trial. No abstract available.
Inhibition by phospholipid liposomes of the prolactin and cortisol response to insulin hypoglycemia in man.
Cavagnini F, Maraschini C, Dubini A, Ramella G, Danesi L, Fossati R. Cavagnini F, et al. Psychopharmacology (Berl). 1984;82(3):157-60. doi: 10.1007/BF00427764. Psychopharmacology (Berl). 1984. PMID: 6425893 Clinical Trial.
In eight normal subjects, we have studied the effects of PL administration (250 mg as IV bolus plus additional 250 mg infused IV over a 60-min period), compared to placebo, on the prolactin (PRL), cortisol and growth hormone (GH) response to an insulin tolerance test (ITT) …
In eight normal subjects, we have studied the effects of PL administration (250 mg as IV bolus plus additional 250 mg infused IV over a
Long-lasting lowering of serum growth hormone and prolactin levels by single and repetitive cabergoline administration in dopamine-responsive acromegalic patients.
Ferrari C, Paracchi A, Romano C, Gerevini G, Boghen M, Barreca A, Fortini P, Dubini A. Ferrari C, et al. Clin Endocrinol (Oxf). 1988 Nov;29(5):467-76. doi: 10.1111/j.1365-2265.1988.tb03695.x. Clin Endocrinol (Oxf). 1988. PMID: 2908102 Clinical Trial.
A control test with a single oral dose of 2.5 mg of bromocriptine was also performed. Cabergoline induced a marked fall in serum PRL level, starting within 3 h and continuing for 7 days after administering 0.3 mg, and for 14 days after 0.6 mg. ...In three poo
A control test with a single oral dose of 2.5 mg of bromocriptine was also performed. Cabergoline induced a marked fall
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