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1,688 results
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Glycopeptide dendrimer colchicine conjugates targeting cancer cells.
Johansson EM, Dubois J, Darbre T, Reymond JL. Johansson EM, et al. Among authors: dubois j. Bioorg Med Chem. 2010 Sep 1;18(17):6589-97. doi: 10.1016/j.bmc.2010.04.026. Epub 2010 Apr 11. Bioorg Med Chem. 2010. PMID: 20674369
Effects of the hydrophobicity of taxoids on their interaction with tubulin.
Guénard D, Thoret S, Dubois J, Adeline MT, Wang Q, Guéritte F. Guénard D, et al. Among authors: dubois j. Bioorg Med Chem. 2000 Jan;8(1):145-56. doi: 10.1016/s0968-0896(99)00279-5. Bioorg Med Chem. 2000. PMID: 10968273
Synthesis of novel macrocyclic docetaxel analogues. Influence of their macrocyclic ring size on tubulin activity.
Querolle O, Dubois J, Thoret S, Roussi F, Montiel-Smith S, Guéritte F, Guénard D. Querolle O, et al. Among authors: dubois j. J Med Chem. 2003 Aug 14;46(17):3623-30. doi: 10.1021/jm030770w. J Med Chem. 2003. PMID: 12904066
Synthesis of C2-C3'N-linked macrocyclic taxoids. Novel docetaxel analogues with high tubulin activity.
Querolle O, Dubois J, Thoret S, Roussi F, Guéritte F, Guénard D. Querolle O, et al. Among authors: dubois j. J Med Chem. 2004 Nov 18;47(24):5937-44. doi: 10.1021/jm0497996. J Med Chem. 2004. PMID: 15537348
Novel C2-C3' N-peptide linked macrocyclic taxoids. Part 1: Synthesis and biological activities of docetaxel analogues with a peptide side chain at C3'.
Larroque AL, Dubois J, Thoret S, Aubert G, Guénard D, Guéritte F. Larroque AL, et al. Among authors: dubois j. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4722-6. doi: 10.1016/j.bmcl.2005.07.069. Bioorg Med Chem Lett. 2005. PMID: 16165352
Novel C2-C3' N-peptide linked macrocyclic taxoids. Part 2: synthesis and biological activities of docetaxel analogues with a peptide side chain at C2 and their macrocyclic derivatives.
Larroque AL, Dubois J, Thoret S, Aubert G, Chiaroni A, Guéritte F, Guénard D. Larroque AL, et al. Among authors: dubois j. Bioorg Med Chem. 2007 Jan 1;15(1):563-74. doi: 10.1016/j.bmc.2006.09.030. Epub 2006 Oct 24. Bioorg Med Chem. 2007. PMID: 17064914
Synthesis and antitumor activity of benzils related to combretastatin A-4.
Mousset C, Giraud A, Provot O, Hamze A, Bignon J, Liu JM, Thoret S, Dubois J, Brion JD, Alami M. Mousset C, et al. Among authors: dubois j. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3266-71. doi: 10.1016/j.bmcl.2008.04.053. Epub 2008 Apr 25. Bioorg Med Chem Lett. 2008. PMID: 18477509
Synthesis and biological evaluation of cis-locked vinylogous combretastatin-A4 analogues: derivatives with a cyclopropyl-vinyl or a cyclopropyl-amide bridge.
Ty N, Kaffy J, Arrault A, Thoret S, Pontikis R, Dubois J, Morin-Allory L, Florent JC. Ty N, et al. Among authors: dubois j. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1318-22. doi: 10.1016/j.bmcl.2009.01.062. Epub 2009 Jan 27. Bioorg Med Chem Lett. 2009. PMID: 19211248
Isocombretastatins a versus combretastatins a: the forgotten isoCA-4 isomer as a highly promising cytotoxic and antitubulin agent.
Messaoudi S, Tréguier B, Hamze A, Provot O, Peyrat JF, De Losada JR, Liu JM, Bignon J, Wdzieczak-Bakala J, Thoret S, Dubois J, Brion JD, Alami M. Messaoudi S, et al. Among authors: dubois j. J Med Chem. 2009 Jul 23;52(14):4538-42. doi: 10.1021/jm900321u. J Med Chem. 2009. PMID: 19530698
Towards the synthesis of bisubstrate inhibitors of protein farnesyltransferase: Synthesis and biological evaluation of new farnesylpyrophosphate analogues.
Duez S, Coudray L, Mouray E, Grellier P, Dubois J. Duez S, et al. Among authors: dubois j. Bioorg Med Chem. 2010 Jan 15;18(2):543-56. doi: 10.1016/j.bmc.2009.12.017. Epub 2009 Dec 11. Bioorg Med Chem. 2010. PMID: 20036564
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