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Lessons from phase III clinical trials on anti-VEGF therapy for cancer.
Jain RK, Duda DG, Clark JW, Loeffler JS. Jain RK, et al. Among authors: duda dg. Nat Clin Pract Oncol. 2006 Jan;3(1):24-40. doi: 10.1038/ncponc0403. Nat Clin Pract Oncol. 2006. PMID: 16407877 Review.
Paracrine regulation of angiogenesis and adipocyte differentiation during in vivo adipogenesis.
Fukumura D, Ushiyama A, Duda DG, Xu L, Tam J, Krishna V, Chatterjee K, Garkavtsev I, Jain RK. Fukumura D, et al. Among authors: duda dg. Circ Res. 2003 Oct 31;93(9):e88-97. doi: 10.1161/01.RES.0000099243.20096.FA. Epub 2003 Oct 2. Circ Res. 2003. PMID: 14525808 Free PMC article.
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer.
Willett CG, Boucher Y, di Tomaso E, Duda DG, Munn LL, Tong RT, Chung DC, Sahani DV, Kalva SP, Kozin SV, Mino M, Cohen KS, Scadden DT, Hartford AC, Fischman AJ, Clark JW, Ryan DP, Zhu AX, Blaszkowsky LS, Chen HX, Shellito PC, Lauwers GY, Jain RK. Willett CG, et al. Among authors: duda dg. Nat Med. 2004 Feb;10(2):145-7. doi: 10.1038/nm988. Epub 2004 Jan 25. Nat Med. 2004. PMID: 14745444 Free PMC article. Clinical Trial.
Role of eNOS in neovascularization: NO for endothelial progenitor cells.
Duda DG, Fukumura D, Jain RK. Duda DG, et al. Trends Mol Med. 2004 Apr;10(4):143-5. doi: 10.1016/j.molmed.2004.02.001. Trends Mol Med. 2004. PMID: 15162796 Review.
Differential transplantability of tumor-associated stromal cells.
Duda DG, Fukumura D, Munn LL, Booth MF, Brown EB, Huang P, Seed B, Jain RK. Duda DG, et al. Cancer Res. 2004 Sep 1;64(17):5920-4. doi: 10.1158/0008-5472.CAN-04-1268. Cancer Res. 2004. PMID: 15342367
Pleiotropy of tissue-specific growth factors: from neurons to vessels via the bone marrow.
Duda DG, Jain RK. Duda DG, et al. J Clin Invest. 2005 Mar;115(3):596-8. doi: 10.1172/JCI24511. J Clin Invest. 2005. PMID: 15765145 Free PMC article.
Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo.
Stroh M, Zimmer JP, Duda DG, Levchenko TS, Cohen KS, Brown EB, Scadden DT, Torchilin VP, Bawendi MG, Fukumura D, Jain RK. Stroh M, et al. Among authors: duda dg. Nat Med. 2005 Jun;11(6):678-82. doi: 10.1038/nm1247. Epub 2005 May 8. Nat Med. 2005. PMID: 15880117 Free PMC article.
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients.
Willett CG, Boucher Y, Duda DG, di Tomaso E, Munn LL, Tong RT, Kozin SV, Petit L, Jain RK, Chung DC, Sahani DV, Kalva SP, Cohen KS, Scadden DT, Fischman AJ, Clark JW, Ryan DP, Zhu AX, Blaszkowsky LS, Shellito PC, Mino-Kenudson M, Lauwers GY. Willett CG, et al. Among authors: duda dg. J Clin Oncol. 2005 Nov 1;23(31):8136-9. doi: 10.1200/JCO.2005.02.5635. J Clin Oncol. 2005. PMID: 16258121 Clinical Trial. No abstract available.
Evidence for incorporation of bone marrow-derived endothelial cells into perfused blood vessels in tumors.
Duda DG, Cohen KS, Kozin SV, Perentes JY, Fukumura D, Scadden DT, Jain RK. Duda DG, et al. Blood. 2006 Apr 1;107(7):2774-6. doi: 10.1182/blood-2005-08-3210. Epub 2005 Dec 8. Blood. 2006. PMID: 16339405 Free PMC article.
Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy.
Duda DG, Cohen KS, di Tomaso E, Au P, Klein RJ, Scadden DT, Willett CG, Jain RK. Duda DG, et al. J Clin Oncol. 2006 Mar 20;24(9):1449-53. doi: 10.1200/JCO.2005.04.2861. J Clin Oncol. 2006. PMID: 16549839 Free PMC article.
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