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Characterization of a novel variant in siblings with Asparagine Synthetase Deficiency.
Sacharow SJ, Dudenhausen EE, Lomelino CL, Rodan L, El Achkar CM, Olson HE, Genetti CA, Agrawal PB, McKenna R, Kilberg MS. Sacharow SJ, et al. Among authors: dudenhausen ee. Mol Genet Metab. 2018 Mar;123(3):317-325. doi: 10.1016/j.ymgme.2017.12.433. Epub 2017 Dec 20. Mol Genet Metab. 2018. PMID: 29279279 Free PMC article.
Amino acid deprivation induces the transcription rate of the human asparagine synthetase gene through a timed program of expression and promoter binding of nutrient-responsive basic region/leucine zipper transcription factors as well as localized histone acetylation.
Chen H, Pan YX, Dudenhausen EE, Kilberg MS. Chen H, et al. Among authors: dudenhausen ee. J Biol Chem. 2004 Dec 3;279(49):50829-39. doi: 10.1074/jbc.M409173200. Epub 2004 Sep 22. J Biol Chem. 2004. PMID: 15385533 Free article.
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