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Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease.
Gehrig S, Duerr J, Weitnauer M, Wagner CJ, Graeber SY, Schatterny J, Hirtz S, Belaaouaj A, Dalpke AH, Schultz C, Mall MA. Gehrig S, et al. Among authors: duerr j. Am J Respir Crit Care Med. 2014 May 1;189(9):1082-92. doi: 10.1164/rccm.201311-1932OC. Am J Respir Crit Care Med. 2014. PMID: 24678594
The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease.
Zhou Z, Duerr J, Johannesson B, Schubert SC, Treis D, Harm M, Graeber SY, Dalpke A, Schultz C, Mall MA. Zhou Z, et al. Among authors: duerr j. J Cyst Fibros. 2011 Jun;10 Suppl 2:S172-82. doi: 10.1016/S1569-1993(11)60021-0. J Cyst Fibros. 2011. PMID: 21658636 Free article. Review.
SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation.
Anagnostopoulou P, Riederer B, Duerr J, Michel S, Binia A, Agrawal R, Liu X, Kalitzki K, Xiao F, Chen M, Schatterny J, Hartmann D, Thum T, Kabesch M, Soleimani M, Seidler U, Mall MA. Anagnostopoulou P, et al. Among authors: duerr j. J Clin Invest. 2012 Oct;122(10):3629-34. doi: 10.1172/JCI60429. Epub 2012 Sep 4. J Clin Invest. 2012. PMID: 22945630 Free PMC article.
Lung arginase expression and activity is increased in cystic fibrosis mouse models.
Jaecklin T, Duerr J, Huang H, Rafii M, Bear CE, Ratjen F, Pencharz P, Kavanagh BP, Mall MA, Grasemann H. Jaecklin T, et al. Among authors: duerr j. J Appl Physiol (1985). 2014 Aug 1;117(3):284-8. doi: 10.1152/japplphysiol.00167.2014. Epub 2014 Jun 12. J Appl Physiol (1985). 2014. PMID: 24925982 Free article.
81 results