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Letter: Possible person-to-person transmission of Creutzfeldt-Jakob disease.
Duffy P, Wolf J, Collins G, DeVoe AG, Streeten B, Cowen D. Duffy P, et al. N Engl J Med. 1974 Mar 21;290(12):692-3. N Engl J Med. 1974. PMID: 4591849 No abstract available.
Parasite burden and severity of malaria in Tanzanian children.
Gonçalves BP, Fried M, Duffy PE. Gonçalves BP, et al. Among authors: duffy pe. N Engl J Med. 2014 Jul 31;371(5):482. doi: 10.1056/NEJMc1407114. N Engl J Med. 2014. PMID: 25075849 Free PMC article. No abstract available.
Parasite burden and severity of malaria in Tanzanian children.
Gonçalves BP, Huang CY, Morrison R, Holte S, Kabyemela E, Prevots DR, Fried M, Duffy PE. Gonçalves BP, et al. Among authors: duffy pe. N Engl J Med. 2014 May 8;370(19):1799-808. doi: 10.1056/NEJMoa1303944. N Engl J Med. 2014. PMID: 24806160 Free PMC article.
METHODS: We documented P. falciparum infection and disease in Tanzanian children followed from birth for an average of 2 years and for as long as 4 years. ...
METHODS: We documented P. falciparum infection and disease in Tanzanian children followed from birth for an average of 2 years and fo …
Malaria during Pregnancy.
Fried M, Duffy PE. Fried M, et al. Among authors: duffy pe. Cold Spring Harb Perspect Med. 2017 Jun 1;7(6):a025551. doi: 10.1101/cshperspect.a025551. Cold Spring Harb Perspect Med. 2017. PMID: 28213434 Free PMC article. Review.
New interventions for malaria: mining the human and parasite genomes.
Ntoumi F, Kwiatkowski DP, Diakité M, Mutabingwa TK, Duffy PE. Ntoumi F, et al. Among authors: duffy pe. Am J Trop Med Hyg. 2007 Dec;77(6 Suppl):270-5. Am J Trop Med Hyg. 2007. PMID: 18165502 Review.
Age-dependent increase in antibodies that inhibit Plasmodium falciparum adhesion to a subset of endothelial receptors.
Attaher O, Mahamar A, Swihart B, Barry A, Diarra BS, Kanoute MB, Dembele AB, Keita S, Gaoussou S, Issiaka D, Dicko A, Duffy PE, Fried M. Attaher O, et al. Among authors: duffy pe. Malar J. 2019 Apr 11;18(1):128. doi: 10.1186/s12936-019-2764-4. Malar J. 2019. PMID: 30971252 Free PMC article.
Malaria in pregnancy: the relevance of animal models for vaccine development.
Doritchamou J, Teo A, Fried M, Duffy PE. Doritchamou J, et al. Among authors: duffy pe. Lab Anim (NY). 2017 Oct 6;46(10):388-398. doi: 10.1038/laban.1349. Lab Anim (NY). 2017. PMID: 28984865 Free PMC article. Review.
Malaria during pregnancy due to Plasmodium falciparum or P. vivax is a major public health problem in endemic areas, with P. falciparum causing the greatest burden of disease. ...
Malaria during pregnancy due to Plasmodium falciparum or P. vivax is a major public health problem in endemic areas, with P. f …
Antibody-independent mechanisms regulate the establishment of chronic Plasmodium infection.
Brugat T, Reid AJ, Lin J, Cunningham D, Tumwine I, Kushinga G, McLaughlin S, Spence P, Böhme U, Sanders M, Conteh S, Bushell E, Metcalf T, Billker O, Duffy PE, Newbold C, Berriman M, Langhorne J. Brugat T, et al. Among authors: duffy pe. Nat Microbiol. 2017 Feb 6;2:16276. doi: 10.1038/nmicrobiol.2016.276. Nat Microbiol. 2017. PMID: 28165471 Free PMC article.
Establishment of chronicity is independent of adaptive immunity and therefore different from the mechanism proposed for maintenance of chronic P. falciparum infections(7-9). ...
Establishment of chronicity is independent of adaptive immunity and therefore different from the mechanism proposed for maintenance of chron …
Expanding the antimalarial toolkit: Targeting host-parasite interactions.
Langhorne J, Duffy PE. Langhorne J, et al. Among authors: duffy pe. J Exp Med. 2016 Feb 8;213(2):143-53. doi: 10.1084/jem.20151677. Epub 2016 Feb 1. J Exp Med. 2016. PMID: 26834158 Free PMC article. Review.
HIV treatments reduce malaria liver stage burden in a non-human primate model of malaria infection at clinically relevant concentrations in vivo.
Hobbs CV, Neal J, Conteh S, Donnelly L, Chen J, Marsh K, Lambert L, Orr-Gonzalez S, Hinderer J, Healy S, Borkowsky W, Penzak SR, Chakravarty S, Hoffman SL, Duffy PE. Hobbs CV, et al. Among authors: duffy pe. PLoS One. 2014 Jul 2;9(7):e100138. doi: 10.1371/journal.pone.0100138. eCollection 2014. PLoS One. 2014. PMID: 24988386 Free PMC article.
We have previously shown that the HIV protease inhibitor lopinavir-ritonavir (LPV-RTV) and the antibiotic trimethoprim sulfamethoxazole (TMP-SMX) inhibit Plasmodium liver stages in rodent malarias and in vitro in P. falciparum. Since clinically relevant levels are better a …
We have previously shown that the HIV protease inhibitor lopinavir-ritonavir (LPV-RTV) and the antibiotic trimethoprim sulfamethoxazole (TMP …
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