Dufresne C - Search Results

1

Discovery, biosynthesis, and mechanism of action of the zaragozic acids: potent inhibitors of squalene synthase.

Bergstrom JD, Dufresne C, Bills GF, Nallin-Omstead M, Byrne K. Bergstrom JD, et al. Among authors: dufresne c. Annu Rev Microbiol. 1995;49:607-39. doi: 10.1146/annurev.mi.49.100195.003135. Annu Rev Microbiol. 1995. PMID: 8561474 Review.

2

Zaragozic acids D and D2: potent inhibitors of squalene synthase and of Ras farnesyl-protein transferase.

Dufresne C, Wilson KE, Singh SB, Zink DL, Bergstrom JD, Rew D, Polishook JD, Meinz M, Huang L, Silverman KC, et al. Dufresne C, et al. J Nat Prod. 1993 Nov;56(11):1923-9. doi: 10.1021/np50101a009. J Nat Prod. 1993. PMID: 8289063

3

Selective protection and relative importance of the carboxylic acid groups of zaragozic acid A for squalene synthase inhibition.

Biftu T, Acton JJ, Berger GD, Bergstrom JD, Dufresne C, Kurtz MM, Marquis RW, Parsons WH, Rew DR, Wilson KE. Biftu T, et al. Among authors: dufresne c. J Med Chem. 1994 Feb 4;37(3):421-4. doi: 10.1021/jm00029a015. J Med Chem. 1994. PMID: 8308869

4

Zaragozic acids: a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase.

Bergstrom JD, Kurtz MM, Rew DJ, Amend AM, Karkas JD, Bostedor RG, Bansal VS, Dufresne C, VanMiddlesworth FL, Hensens OD, et al. Bergstrom JD, et al. Among authors: dufresne c. Proc Natl Acad Sci U S A. 1993 Jan 1;90(1):80-4. doi: 10.1073/pnas.90.1.80. Proc Natl Acad Sci U S A. 1993. PMID: 8419946 Free PMC article.

5

Automated agar plate streaker: a linear plater on Society for Biomolecular Sciences standard plates.

King GW, Kath GS, Siciliano S, Simpson N, Masurekar P, Sigmund J, Polishook J, Skwish S, Bills G, Genilloud O, Peláez F, Martín J, Dufresne C. King GW, et al. Among authors: dufresne c. J Biomol Screen. 2006 Sep;11(6):704-11. doi: 10.1177/1087057106289288. Epub 2006 Jul 14. J Biomol Screen. 2006. PMID: 16844965

6

Restricticin, a novel glycine-containing antifungal agent.

Schwartz RE, Dufresne C, Flor JE, Kempf AJ, Wilson KE, Lam T, Onishi J, Milligan J, Fromtling RA, Abruzzo GK, et al. Schwartz RE, et al. Among authors: dufresne c. J Antibiot (Tokyo). 1991 May;44(5):463-71. doi: 10.7164/antibiotics.44.463. J Antibiot (Tokyo). 1991. PMID: 2061189 Free article.

7

The design and development of an integrated natural products screening database.

Holt TG, Dufresne C, Liesch JM, Mallow GK. Holt TG, et al. Among authors: dufresne c. J Biomol Screen. 2000 Dec;5(6):421-33. doi: 10.1177/108705710000500605. J Biomol Screen. 2000. PMID: 11598460

8

Metabolic profiles of montelukast sodium (Singulair), a potent cysteinyl leukotriene1 receptor antagonist, in human plasma and bile.

Balani SK, Xu X, Pratha V, Koss MA, Amin RD, Dufresne C, Miller RR, Arison BH, Doss GA, Chiba M, Freeman A, Holland SD, Schwartz JI, Lasseter KC, Gertz BJ, Isenberg JI, Rogers JD, Lin JH, Baillie TA. Balani SK, et al. Among authors: dufresne c. Drug Metab Dispos. 1997 Nov;25(11):1282-7. Drug Metab Dispos. 1997. PMID: 9351905 Clinical Trial.

9

L-741,494, a fungal metabolite that is an inhibitor of interleukin-1 beta converting enzyme.

Salvatore MJ, Hensens OD, Zink DL, Liesch J, Dufresne C, Ondeyka JG, Jürgens TM, Borris RP, Raghoobar S, McCauley E, et al. Salvatore MJ, et al. Among authors: dufresne c. J Nat Prod. 1994 Jun;57(6):755-60. doi: 10.1021/np50108a011. J Nat Prod. 1994. PMID: 7931364

10

The planning and establishment of a sample preparation laboratory for drug discovery.

Dufresne C. Dufresne C. J Autom Methods Manag Chem. 2000;22(6):175-9. doi: 10.1155/S1463924600000316. J Autom Methods Manag Chem. 2000. PMID: 18924691 Free PMC article.

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