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Hyperforin and its analogues inhibit CYP3A4 enzyme activity.
Lee JY, Duke RK, Tran VH, Hook JM, Duke CC. Lee JY, et al. Among authors: duke rk, duke cc. Phytochemistry. 2006 Dec;67(23):2550-60. doi: 10.1016/j.phytochem.2006.09.018. Epub 2006 Nov 2. Phytochemistry. 2006. PMID: 17083953
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