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Page 1
Therapeutic potential of curcumin in digestive diseases.
Dulbecco P, Savarino V. Dulbecco P, et al. World J Gastroenterol. 2013 Dec 28;19(48):9256-70. doi: 10.3748/wjg.v19.i48.9256. World J Gastroenterol. 2013. PMID: 24409053 Free PMC article. Review.
Curcumin is a low-molecular-weight hydrophobic polyphenol that is extracted from turmeric, which possesses a wide range of biological properties including anti-inflammatory, anti-oxidant, anti-proliferative and anti-microbial activities. ...This allows us to achieve much g …
Curcumin is a low-molecular-weight hydrophobic polyphenol that is extracted from turmeric, which possesses a wide range of biological …
Curcumin alleviates the aggressiveness of breast cancer through inhibiting cell adhesion mediated by TEAD4-fibronectin axis.
Li M, Chen L, Wang M, Huang X, Ke Q, Hu C. Li M, et al. Biochem Pharmacol. 2025 Feb;232:116690. doi: 10.1016/j.bcp.2024.116690. Epub 2024 Nov 29. Biochem Pharmacol. 2025. PMID: 39617209
However, its effects and the underlying mechanisms on BC metastasis remain unknown. Here, we show that curcumin reduced the abilities of migration and invasion of BC cells as well as lung metastasis of BC in nude mice by TEAD4 induced. ...Our work demonstrates that TEAD4 c …
However, its effects and the underlying mechanisms on BC metastasis remain unknown. Here, we show that curcumin reduced the abilities …
Curcumin attenuates replicative senescence in human dental follicle cells and restores their osteogenic differentiation.
Dasi D, Nallabelli N, Devalaraju R, K N S, Ghosh S, Karnati R, Sreenivasa Rao P. Dasi D, et al. J Oral Biosci. 2023 Dec;65(4):371-378. doi: 10.1016/j.job.2023.10.001. Epub 2023 Oct 6. J Oral Biosci. 2023. PMID: 37806337
OBJECTIVE: This study aimed to examine the therapeutic effects of curcumin against replicative senescence in dental follicle cells (DFCs). METHODS: Human DFCs were cultured in Dulbecco's Modified Eagle Medium with growth supplements. ...Using western-blot ana …
OBJECTIVE: This study aimed to examine the therapeutic effects of curcumin against replicative senescence in dental follicle cells (D …
Curcumin pre-treatment may protect against mitochondrial damage in LRRK2-mutant Parkinson's disease and healthy control fibroblasts.
Abrahams S, Miller HC, Lombard C, van der Westhuizen FH, Bardien S. Abrahams S, et al. Biochem Biophys Rep. 2021 Jun 16;27:101035. doi: 10.1016/j.bbrep.2021.101035. eCollection 2021 Sep. Biochem Biophys Rep. 2021. PMID: 34189277 Free PMC article.
The fibroblasts were exposed to five treatment groups, (i) untreated, (ii) curcumin only, (iii) paraquat only, (iv) pre-curcumin group: with curcumin for 2hr followed by paraquat for 24hr and (v) post-curcumin group: with paraquat for 24hr followed by …
The fibroblasts were exposed to five treatment groups, (i) untreated, (ii) curcumin only, (iii) paraquat only, (iv) pre-curcumin …
BODIPY-Tagged Platinum(II) Curcumin Complexes for Endoplasmic Reticulum-Targeted Red Light PDT.
Upadhyay A, Kundu P, Ramu V, Kondaiah P, Chakravarty AR. Upadhyay A, et al. Inorg Chem. 2022 Jan 24;61(3):1335-1348. doi: 10.1021/acs.inorgchem.1c02745. Epub 2022 Jan 6. Inorg Chem. 2022. PMID: 34990135
[Pt(RB)(Cur)]NO(3) (RBC), [Pt(IRB)(Cur)]NO(3) (IRBC), and [Pt(L)(Cur)]NO(3) (PBC), where HCur is curcumin, L is 1-benzyl-2-(2-pyridyl)benzimidazole, and RB and IRB are red-light-active non-iodo and diiodo-BODIPY tagged to L, respectively, were synthesized and characterized …
[Pt(RB)(Cur)]NO(3) (RBC), [Pt(IRB)(Cur)]NO(3) (IRBC), and [Pt(L)(Cur)]NO(3) (PBC), where HCur is curcumin, L is 1-benzyl-2-(2-pyridyl …
Curcumin prevents experimental autoimmune encephalomyelitis by inhibiting proliferation and effector CD4+ T cell activation.
Liu JQ, Yan YQ, Liu JT, Wang YR, Wang X. Liu JQ, et al. Eur Rev Med Pharmacol Sci. 2019 Oct;23(20):9108-9116. doi: 10.26355/eurrev_201910_19314. Eur Rev Med Pharmacol Sci. 2019. PMID: 31696502 Free article.
Curcumin has great potential in MS treatment. Little is known about the effect of curcumin on MS. Therefore, we investigated the effect of curcumin on MS, especially on CD4+ T cells. MATERIALS AND METHODS: CD4+ T cells (TH1, TH17, and Treg cells) were culture …
Curcumin has great potential in MS treatment. Little is known about the effect of curcumin on MS. Therefore, we investigated t …
Anti-cancer effect of nano-encapsulated boswellic acids, curcumin and naringenin against HepG-2 cell line.
Elnawasany S, Haggag YA, Shalaby SM, Soliman NA, El Saadany AA, Ibrahim MAA, Badria F. Elnawasany S, et al. BMC Complement Med Ther. 2023 Jul 29;23(1):270. doi: 10.1186/s12906-023-04096-4. BMC Complement Med Ther. 2023. PMID: 37516826 Free PMC article.
We conducted this in vitro study to assess the effect of three natural products: Boswellic acids, curcumin and naringin versus corresponding nanoparticles (NPs) on Hep G2 cells proliferation. METHODS: Boswellic acid, curcumin, naringin-loaded NPs were prepared using …
We conducted this in vitro study to assess the effect of three natural products: Boswellic acids, curcumin and naringin versus corres …
Exploitation of traditional healing properties, using the nanotechnology's advantages: The case of curcumin.
Liakopoulou A, Mourelatou E, Hatziantoniou S. Liakopoulou A, et al. Toxicol Rep. 2021 May 28;8:1143-1155. doi: 10.1016/j.toxrep.2021.05.012. eCollection 2021. Toxicol Rep. 2021. PMID: 34150524 Free PMC article.
Curcumin (CUR) has a long history of use as an antimicrobial, anti-inflammatory and wound healing agent, for the treatment of various skin conditions. ...Lipid nanocarriers with different matrix fluidity (Solid Lipid Nanoparticles; SLN, Nanostructured Lipid Carriers; NLC, …
Curcumin (CUR) has a long history of use as an antimicrobial, anti-inflammatory and wound healing agent, for the treatment of various …
Photocytotoxic cancer cell-targeting platinum(ii) complexes of glucose-appended curcumin and biotinylated 1,10-phenanthroline.
Upadhyay A , Gautam S , Ramu V , Kondaiah P , Chakravarty AR . Upadhyay A , et al. Dalton Trans. 2019 Dec 3;48(47):17556-17565. doi: 10.1039/c9dt03490k. Dalton Trans. 2019. PMID: 31748772
Complexes 2-4 showed absorption bands within 410-430 nm (epsilon, 2.1 104 to 2.8 104 M-1 cm-1) in 10% DMSO-DPBS (Dulbecco's phosphate-buffered saline) and emission bands near 530 nm (lambdaex = 410-430 nm) with a fluorescence quantum yield (phiF) value of 0.02. The …
Complexes 2-4 showed absorption bands within 410-430 nm (epsilon, 2.1 104 to 2.8 104 M-1 cm-1) in 10% DMSO-DPBS (Dulbecco's ph …
Dietary antioxidants as a source of hydrogen peroxide.
Grzesik M, Bartosz G, Stefaniuk I, Pichla M, Namieśnik J, Sadowska-Bartosz I. Grzesik M, et al. Food Chem. 2019 Apr 25;278:692-699. doi: 10.1016/j.foodchem.2018.11.109. Epub 2018 Nov 30. Food Chem. 2019. PMID: 30583431
Studies of 54 antioxidants revealed that 27 of them, mainly polyphenols, generated hydrogen peroxide (H(2)O(2)) when added to Dulbecco's modified Eagle's medium (DMEM), other media used for culture of mammalian and yeast cells and phosphate-buffered saline. ...
Studies of 54 antioxidants revealed that 27 of them, mainly polyphenols, generated hydrogen peroxide (H(2)O(2)) when added to Dulbecco …
21 results