Structural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognition.
Merithew E, Hatherly S, Dumas JJ, Lawe DC, Heller-Harrison R, Lambright DG.
Merithew E, et al. Among authors: dumas jj.
J Biol Chem. 2001 Apr 27;276(17):13982-8. doi: 10.1074/jbc.M009771200. Epub 2001 Jan 25.
J Biol Chem. 2001.
PMID: 11278565
Free article.
We have previously shown that the active conformation of Rab3A is stabilized by a substantial hydrophobic interface between the putative conformational switch regions (Dumas, J. J., Zhu, Z., Connolly, J. L., and Lambright, D. G. (1999) Structure 7, 413 …
We have previously shown that the active conformation of Rab3A is stabilized by a substantial hydrophobic interface between the putative con …