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The farnesoid X receptor regulates adipocyte differentiation and function by promoting peroxisome proliferator-activated receptor-gamma and interfering with the Wnt/beta-catenin pathways.
Abdelkarim M, Caron S, Duhem C, Prawitt J, Dumont J, Lucas A, Bouchaert E, Briand O, Brozek J, Kuipers F, Fievet C, Cariou B, Staels B. Abdelkarim M, et al. Among authors: dumont j. J Biol Chem. 2010 Nov 19;285(47):36759-67. doi: 10.1074/jbc.M110.166231. Epub 2010 Sep 17. J Biol Chem. 2010. PMID: 20851881 Free PMC article.
FXR-deficiency confers increased susceptibility to torpor.
Cariou B, Bouchaert E, Abdelkarim M, Dumont J, Caron S, Fruchart JC, Burcelin R, Kuipers F, Staels B. Cariou B, et al. Among authors: dumont j. FEBS Lett. 2007 Nov 13;581(27):5191-8. doi: 10.1016/j.febslet.2007.09.064. Epub 2007 Oct 12. FEBS Lett. 2007. PMID: 17950284
Is the ornithine transcarbamylase gene a genetic determinant of Alzheimer's disease?
Hansmannel F, Lendon C, Pasquier F, Dumont J, Hannequin D, Chapuis J, Laumet G, Ayral AM, Galimberti D, Scarpini E, Campion D, Amouyel P, Lambert JC. Hansmannel F, et al. Among authors: dumont j. Neurosci Lett. 2009 Jan 2;449(1):76-80. doi: 10.1016/j.neulet.2008.10.081. Epub 2008 Oct 28. Neurosci Lett. 2009. PMID: 18983895
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