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263 results
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Adaptor usage and Toll-like receptor signaling specificity.
Dunne A, O'Neill LA. Dunne A, et al. FEBS Lett. 2005 Jun 13;579(15):3330-5. doi: 10.1016/j.febslet.2005.04.024. Epub 2005 Apr 26. FEBS Lett. 2005. PMID: 15876435 Review.
The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense.
Dunne A, O'Neill LA. Dunne A, et al. Sci STKE. 2003 Feb 25;2003(171):re3. doi: 10.1126/stke.2003.171.re3. Sci STKE. 2003. PMID: 12606705 Review.
Mal and MyD88: adapter proteins involved in signal transduction by Toll-like receptors.
O'Neill LA, Dunne A, Edjeback M, Gray P, Jefferies C, Wietek C. O'Neill LA, et al. Among authors: dunne a. J Endotoxin Res. 2003;9(1):55-9. doi: 10.1179/096805103125001351. J Endotoxin Res. 2003. PMID: 12691620 Review.
Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4.
Jefferies CA, Doyle S, Brunner C, Dunne A, Brint E, Wietek C, Walch E, Wirth T, O'Neill LA. Jefferies CA, et al. Among authors: dunne a. J Biol Chem. 2003 Jul 11;278(28):26258-64. doi: 10.1074/jbc.M301484200. Epub 2003 Apr 30. J Biol Chem. 2003. PMID: 12724322
Structural complementarity of Toll/interleukin-1 receptor domains in Toll-like receptors and the adaptors Mal and MyD88.
Dunne A, Ejdeback M, Ludidi PL, O'Neill LA, Gay NJ. Dunne A, et al. J Biol Chem. 2003 Oct 17;278(42):41443-51. doi: 10.1074/jbc.M301742200. Epub 2003 Jul 29. J Biol Chem. 2003. PMID: 12888566
ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance.
Brint EK, Xu D, Liu H, Dunne A, McKenzie AN, O'Neill LA, Liew FY. Brint EK, et al. Among authors: dunne a. Nat Immunol. 2004 Apr;5(4):373-9. doi: 10.1038/ni1050. Epub 2004 Mar 7. Nat Immunol. 2004. PMID: 15004556
New insights into the post-translational modification of Toll-like receptor signaling molecules.
Dunne A, O'Neill L. Dunne A, et al. J Endotoxin Res. 2005;11(6):325-32. doi: 10.1179/096805105X58742. J Endotoxin Res. 2005. PMID: 16303087 Review.
MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction.
Gray P, Dunne A, Brikos C, Jefferies CA, Doyle SL, O'Neill LA. Gray P, et al. Among authors: dunne a. J Biol Chem. 2006 Apr 14;281(15):10489-95. doi: 10.1074/jbc.M508892200. Epub 2006 Jan 26. J Biol Chem. 2006. PMID: 16439361
NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.
Miggin SM, PĂ„lsson-McDermott E, Dunne A, Jefferies C, Pinteaux E, Banahan K, Murphy C, Moynagh P, Yamamoto M, Akira S, Rothwell N, Golenbock D, Fitzgerald KA, O'Neill LA. Miggin SM, et al. Among authors: dunne a. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3372-7. doi: 10.1073/pnas.0608100104. Epub 2007 Feb 20. Proc Natl Acad Sci U S A. 2007. PMID: 17360653 Free PMC article.
TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain.
Carpenter S, Carlson T, Dellacasagrande J, Garcia A, Gibbons S, Hertzog P, Lyons A, Lin LL, Lynch M, Monie T, Murphy C, Seidl KJ, Wells C, Dunne A, O'Neill LA. Carpenter S, et al. Among authors: dunne a. J Immunol. 2009 Sep 15;183(6):3989-95. doi: 10.4049/jimmunol.0901518. Epub 2009 Aug 26. J Immunol. 2009. PMID: 19710467
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