Duran Y - Search Results

1

Effective gene therapy with nonintegrating lentiviral vectors.

Yáñez-Muñoz RJ, Balaggan KS, MacNeil A, Howe SJ, Schmidt M, Smith AJ, Buch P, MacLaren RE, Anderson PN, Barker SE, Duran Y, Bartholomae C, von Kalle C, Heckenlively JR, Kinnon C, Ali RR, Thrasher AJ. Yáñez-Muñoz RJ, et al. Among authors: duran y. Nat Med. 2006 Mar;12(3):348-53. doi: 10.1038/nm1365. Epub 2006 Feb 19. Nat Med. 2006. PMID: 16491086

2

Absence of ocular malignant transformation after sub-retinal delivery of rAAV2/2 or integrating lentiviral vectors in p53-deficient mice.

Balaggan KS, Duran Y, Georgiadis A, Thaung C, Barker SE, Buch PK, MacNeil A, Robbie S, Bainbridge JW, Smith AJ, Ali RR. Balaggan KS, et al. Among authors: duran y. Gene Ther. 2012 Feb;19(2):182-8. doi: 10.1038/gt.2011.194. Epub 2011 Nov 24. Gene Ther. 2012. PMID: 22113317

3

Subretinal delivery of adeno-associated virus serotype 2 results in minimal immune responses that allow repeat vector administration in immunocompetent mice.

Barker SE, Broderick CA, Robbie SJ, Duran Y, Natkunarajah M, Buch P, Balaggan KS, MacLaren RE, Bainbridge JW, Smith AJ, Ali RR. Barker SE, et al. Among authors: duran y. J Gene Med. 2009 Jun;11(6):486-97. doi: 10.1002/jgm.1327. J Gene Med. 2009. PMID: 19340848 Free PMC article.

4

Assessment of ocular transduction using single-stranded and self-complementary recombinant adeno-associated virus serotype 2/8.

Natkunarajah M, Trittibach P, McIntosh J, Duran Y, Barker SE, Smith AJ, Nathwani AC, Ali RR. Natkunarajah M, et al. Among authors: duran y. Gene Ther. 2008 Mar;15(6):463-7. doi: 10.1038/sj.gt.3303074. Epub 2007 Nov 15. Gene Ther. 2008. PMID: 18004402

5

Lentiviral-vector-mediated expression of murine IL-1 receptor antagonist or IL-10 reduces the severity of endotoxin-induced uveitis.

Trittibach P, Barker SE, Broderick CA, Natkunarajah M, Duran Y, Robbie SJ, Bainbridge JW, Smith AJ, Sarra GM, Dick AD, Ali RR. Trittibach P, et al. Among authors: duran y. Gene Ther. 2008 Nov;15(22):1478-88. doi: 10.1038/gt.2008.109. Epub 2008 Jun 26. Gene Ther. 2008. PMID: 18580969 Free PMC article.

6

Manipulation of the recipient retinal environment by ectopic expression of neurotrophic growth factors can improve transplanted photoreceptor integration and survival.

West EL, Pearson RA, Duran Y, Gonzalez-Cordero A, MacLaren RE, Smith AJ, Sowden JC, Ali RR. West EL, et al. Among authors: duran y. Cell Transplant. 2012;21(5):871-87. doi: 10.3727/096368911X623871. Epub 2012 Feb 2. Cell Transplant. 2012. PMID: 22325046 Free PMC article.

7

In contrast to AAV-mediated Cntf expression, AAV-mediated Gdnf expression enhances gene replacement therapy in rodent models of retinal degeneration.

Buch PK, MacLaren RE, Durán Y, Balaggan KS, MacNeil A, Schlichtenbrede FC, Smith AJ, Ali RR. Buch PK, et al. Among authors: duran y. Mol Ther. 2006 Nov;14(5):700-9. doi: 10.1016/j.ymthe.2006.05.019. Epub 2006 Jul 26. Mol Ther. 2006. PMID: 16872907 Free article.

8

Long-term survival of photoreceptors transplanted into the adult murine neural retina requires immune modulation.

West EL, Pearson RA, Barker SE, Luhmann UF, Maclaren RE, Barber AC, Duran Y, Smith AJ, Sowden JC, Ali RR. West EL, et al. Among authors: duran y. Stem Cells. 2010 Nov;28(11):1997-2007. doi: 10.1002/stem.520. Stem Cells. 2010. PMID: 20857496 Free PMC article.

9

Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina.

Gonzalez-Cordero A, West EL, Pearson RA, Duran Y, Carvalho LS, Chu CJ, Naeem A, Blackford SJI, Georgiadis A, Lakowski J, Hubank M, Smith AJ, Bainbridge JWB, Sowden JC, Ali RR. Gonzalez-Cordero A, et al. Among authors: duran y. Nat Biotechnol. 2013 Aug;31(8):741-7. doi: 10.1038/nbt.2643. Epub 2013 Jul 21. Nat Biotechnol. 2013. PMID: 23873086 Free PMC article.

10

EIAV vector-mediated delivery of endostatin or angiostatin inhibits angiogenesis and vascular hyperpermeability in experimental CNV.

Balaggan KS, Binley K, Esapa M, MacLaren RE, Iqball S, Duran Y, Pearson RA, Kan O, Barker SE, Smith AJ, Bainbridge JW, Naylor S, Ali RR. Balaggan KS, et al. Among authors: duran y. Gene Ther. 2006 Aug;13(15):1153-65. doi: 10.1038/sj.gt.3302769. Epub 2006 Jun 13. Gene Ther. 2006. PMID: 16572190

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