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The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death.
Panaretakis T, Joza N, Modjtahedi N, Tesniere A, Vitale I, Durchschlag M, Fimia GM, Kepp O, Piacentini M, Froehlich KU, van Endert P, Zitvogel L, Madeo F, Kroemer G. Panaretakis T, et al. Among authors: durchschlag m. Cell Death Differ. 2008 Sep;15(9):1499-509. doi: 10.1038/cdd.2008.67. Epub 2008 May 9. Cell Death Differ. 2008. PMID: 18464797
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death.
Panaretakis T, Kepp O, Brockmeier U, Tesniere A, Bjorklund AC, Chapman DC, Durchschlag M, Joza N, Pierron G, van Endert P, Yuan J, Zitvogel L, Madeo F, Williams DB, Kroemer G. Panaretakis T, et al. Among authors: durchschlag m. EMBO J. 2009 Mar 4;28(5):578-90. doi: 10.1038/emboj.2009.1. Epub 2009 Jan 22. EMBO J. 2009. PMID: 19165151 Free PMC article.
Immunogenic calreticulin exposure occurs through a phylogenetically conserved stress pathway involving the chemokine CXCL8.
Sukkurwala AQ, Martins I, Wang Y, Schlemmer F, Ruckenstuhl C, Durchschlag M, Michaud M, Senovilla L, Sistigu A, Ma Y, Vacchelli E, Sulpice E, Gidrol X, Zitvogel L, Madeo F, Galluzzi L, Kepp O, Kroemer G. Sukkurwala AQ, et al. Among authors: durchschlag m. Cell Death Differ. 2014 Jan;21(1):59-68. doi: 10.1038/cdd.2013.73. Epub 2013 Jun 21. Cell Death Differ. 2014. PMID: 23787997 Free PMC article.
Vacuolar functions determine the mode of cell death.
Schauer A, Knauer H, Ruckenstuhl C, Fussi H, Durchschlag M, Potocnik U, Fröhlich KU. Schauer A, et al. Among authors: durchschlag m. Biochim Biophys Acta. 2009 Mar;1793(3):540-5. doi: 10.1016/j.bbamcr.2008.11.006. Epub 2008 Nov 27. Biochim Biophys Acta. 2009. PMID: 19100296 Free article.