Durrant DE - Search Results

1

Targeting the Raf kinases in human cancer: the Raf dimer dilemma.

Durrant DE, Morrison DK. Durrant DE, et al. Br J Cancer. 2018 Jan;118(1):3-8. doi: 10.1038/bjc.2017.399. Epub 2017 Dec 14. Br J Cancer. 2018. PMID: 29235562 Free PMC article. Review.

2

Inhibition of Ras/Raf/MEK/ERK Pathway Signaling by a Stress-Induced Phospho-Regulatory Circuit.

Ritt DA, Abreu-Blanco MT, Bindu L, Durrant DE, Zhou M, Specht SI, Stephen AG, Holderfield M, Morrison DK. Ritt DA, et al. Among authors: durrant de. Mol Cell. 2016 Dec 1;64(5):875-887. doi: 10.1016/j.molcel.2016.10.029. Epub 2016 Nov 23. Mol Cell. 2016. PMID: 27889448 Free PMC article.

3

cis-3, 4', 5-Trimethoxy-3'-aminostilbene disrupts tumor vascular perfusion without damaging normal organ perfusion.

Durrant D, Corwin F, Simoni D, Zhao M, Rudek MA, Salloum FN, Kukreja RC, Fatouros PP, Lee RM. Durrant D, et al. Cancer Chemother Pharmacol. 2009 Jan;63(2):191-200. doi: 10.1007/s00280-008-0726-6. Epub 2008 Mar 26. Cancer Chemother Pharmacol. 2009. PMID: 18365199

4

Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity.

Tripathi A, Durrant D, Lee RM, Baruchello R, Romagnoli R, Simoni D, Kellogg GE. Tripathi A, et al. J Enzyme Inhib Med Chem. 2009 Dec;24(6):1237-44. doi: 10.3109/14756360902787055. J Enzyme Inhib Med Chem. 2009. PMID: 19912057 Free PMC article.

5

Dietary inorganic nitrate alleviates doxorubicin cardiotoxicity: mechanisms and implications.

Xi L, Zhu SG, Das A, Chen Q, Durrant D, Hobbs DC, Lesnefsky EJ, Kukreja RC. Xi L, et al. Nitric Oxide. 2012 May 15;26(4):274-84. doi: 10.1016/j.niox.2012.03.006. Epub 2012 Apr 5. Nitric Oxide. 2012. PMID: 22484629 Free PMC article. Review.

6

Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction.

Das A, Durrant D, Mitchell C, Mayton E, Hoke NN, Salloum FN, Park MA, Qureshi I, Lee R, Dent P, Kukreja RC. Das A, et al. Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18202-7. doi: 10.1073/pnas.1006965107. Epub 2010 Sep 30. Proc Natl Acad Sci U S A. 2010. PMID: 20884855 Free PMC article.

7

Long-acting phosphodiesterase-5 inhibitor tadalafil attenuates doxorubicin-induced cardiomyopathy without interfering with chemotherapeutic effect.

Koka S, Das A, Zhu SG, Durrant D, Xi L, Kukreja RC. Koka S, et al. J Pharmacol Exp Ther. 2010 Sep 1;334(3):1023-30. doi: 10.1124/jpet.110.170191. Epub 2010 Jun 11. J Pharmacol Exp Ther. 2010. PMID: 20543097 Free PMC article.

8

Chronic treatment with novel nanoformulated micelles of rapamycin, Rapatar, protects diabetic heart against ischaemia/reperfusion injury.

Samidurai A, Salloum FN, Durrant D, Chernova OB, Kukreja RC, Das A. Samidurai A, et al. Br J Pharmacol. 2017 Dec;174(24):4771-4784. doi: 10.1111/bph.14059. Epub 2017 Nov 24. Br J Pharmacol. 2017. PMID: 28967097 Free PMC article.

9

PDE5 inhibitors as therapeutics for heart disease, diabetes and cancer.

Das A, Durrant D, Salloum FN, Xi L, Kukreja RC. Das A, et al. Pharmacol Ther. 2015 Mar;147:12-21. doi: 10.1016/j.pharmthera.2014.10.003. Epub 2014 Oct 31. Pharmacol Ther. 2015. PMID: 25444755 Free PMC article. Review.

10

Stilbene 5c, a microtubule poison with vascular disrupting properties that induces multiple modes of growth arrest and cell death.

Alotaibi MR, Asnake B, Di X, Beckman MJ, Durrant D, Simoni D, Baruchello R, Lee RM, Schwartz EL, Gewirtz DA. Alotaibi MR, et al. Biochem Pharmacol. 2013 Dec 15;86(12):1688-98. doi: 10.1016/j.bcp.2013.10.007. Epub 2013 Oct 19. Biochem Pharmacol. 2013. PMID: 24144631 Free PMC article.

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