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285 results
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Human cholesterol metabolism and therapeutic molecules.
Charlton-Menys V, Durrington PN. Charlton-Menys V, et al. Among authors: durrington pn. Exp Physiol. 2008 Jan;93(1):27-42. doi: 10.1113/expphysiol.2007.035147. Exp Physiol. 2008. PMID: 18165431 Review.
Non-HDL cholesterol should not generally replace LDL cholesterol in the management of hyperlipidaemia.
Soran H, Ho JH, Adam S, Durrington PN. Soran H, et al. Among authors: durrington pn. Curr Opin Lipidol. 2019 Aug;30(4):263-272. doi: 10.1097/MOL.0000000000000614. Curr Opin Lipidol. 2019. PMID: 31219837 Review.
Acquired low cholesterol: diagnosis and relevance to safety of low LDL therapeutic targets.
Soran H, Ho JH, Durrington PN. Soran H, et al. Among authors: durrington pn. Curr Opin Lipidol. 2018 Aug;29(4):318-326. doi: 10.1097/MOL.0000000000000526. Curr Opin Lipidol. 2018. PMID: 29746303 Review.
Evidence for more intensive cholesterol lowering.
Soran H, Kwok S, Adam S, Ho JH, Durrington PN. Soran H, et al. Among authors: durrington pn. Curr Opin Lipidol. 2017 Aug;28(4):291-299. doi: 10.1097/MOL.0000000000000433. Curr Opin Lipidol. 2017. PMID: 28509674 Review.
Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.
Postmus I, Trompet S, Deshmukh HA, Barnes MR, Li X, Warren HR, Chasman DI, Zhou K, Arsenault BJ, Donnelly LA, Wiggins KL, Avery CL, Griffin P, Feng Q, Taylor KD, Li G, Evans DS, Smith AV, de Keyser CE, Johnson AD, de Craen AJ, Stott DJ, Buckley BM, Ford I, Westendorp RG, Slagboom PE, Sattar N, Munroe PB, Sever P, Poulter N, Stanton A, Shields DC, O'Brien E, Shaw-Hawkins S, Chen YD, Nickerson DA, Smith JD, Dubé MP, Boekholdt SM, Hovingh GK, Kastelein JJ, McKeigue PM, Betteridge J, Neil A, Durrington PN, Doney A, Carr F, Morris A, McCarthy MI, Groop L, Ahlqvist E; Welcome Trust Case Control Consortium, Bis JC, Rice K, Smith NL, Lumley T, Whitsel EA, Stürmer T, Boerwinkle E, Ngwa JS, O'Donnell CJ, Vasan RS, Wei WQ, Wilke RA, Liu CT, Sun F, Guo X, Heckbert SR, Post W, Sotoodehnia N, Arnold AM, Stafford JM, Ding J, Herrington DM, Kritchevsky SB, Eiriksdottir G, Launer LJ, Harris TB, Chu AY, Giulianini F, MacFadyen JG, Barratt BJ, Nyberg F, Stricker BH, Uitterlinden AG, Hofman A, Rivadeneira F, Emilsson V, Franco OH, Ridker PM, Gudnason V, Liu Y, Denny JC, Ballantyne CM, Rotter JI, Adrienne Cupples L, Psaty BM, Palmer CN, Tardif JC, Colhoun HM, Hitman G, Krauss RM, Wouter Jukema J, Caulfield MJ. Postmus I, et al. Among authors: durrington pn. Nat Commun. 2014 Oct 28;5:5068. doi: 10.1038/ncomms6068. Nat Commun. 2014. PMID: 25350695 Free PMC article.
The importance of considering LDL cholesterol response as well as cardiovascular risk in deciding who can benefit from statin therapy.
Soran H, Schofield JD, Durrington PN. Soran H, et al. Among authors: durrington pn. Curr Opin Lipidol. 2014 Aug;25(4):239-46. doi: 10.1097/MOL.0000000000000097. Curr Opin Lipidol. 2014. PMID: 24978144 Review.
Susceptibility of LDL and its subfractions to glycation.
Soran H, Durrington PN. Soran H, et al. Among authors: durrington pn. Curr Opin Lipidol. 2011 Aug;22(4):254-61. doi: 10.1097/MOL.0b013e328348a43f. Curr Opin Lipidol. 2011. PMID: 21734572 Review.
Meta-analysis of genome-wide association studies of HDL cholesterol response to statins.
Postmus I, Warren HR, Trompet S, Arsenault BJ, Avery CL, Bis JC, Chasman DI, de Keyser CE, Deshmukh HA, Evans DS, Feng Q, Li X, Smit RA, Smith AV, Sun F, Taylor KD, Arnold AM, Barnes MR, Barratt BJ, Betteridge J, Boekholdt SM, Boerwinkle E, Buckley BM, Chen YI, de Craen AJ, Cummings SR, Denny JC, Dubé MP, Durrington PN, Eiriksdottir G, Ford I, Guo X, Harris TB, Heckbert SR, Hofman A, Hovingh GK, Kastelein JJ, Launer LJ, Liu CT, Liu Y, Lumley T, McKeigue PM, Munroe PB, Neil A, Nickerson DA, Nyberg F, O'Brien E, O'Donnell CJ, Post W, Poulter N, Vasan RS, Rice K, Rich SS, Rivadeneira F, Sattar N, Sever P, Shaw-Hawkins S, Shields DC, Slagboom PE, Smith NL, Smith JD, Sotoodehnia N, Stanton A, Stott DJ, Stricker BH, Stürmer T, Uitterlinden AG, Wei WQ, Westendorp RG, Whitsel EA, Wiggins KL, Wilke RA, Ballantyne CM, Colhoun HM, Cupples LA, Franco OH, Gudnason V, Hitman G, Palmer CN, Psaty BM, Ridker PM, Stafford JM, Stein CM, Tardif JC, Caulfield MJ, Jukema JW, Rotter JI, Krauss RM. Postmus I, et al. Among authors: durrington pn. J Med Genet. 2016 Dec;53(12):835-845. doi: 10.1136/jmedgenet-2016-103966. Epub 2016 Sep 1. J Med Genet. 2016. PMID: 27587472 Free PMC article.
A comparison of the effects of low- and high-dose atorvastatin on lipoprotein metabolism and inflammatory cytokines in type 2 diabetes: Results from the Protection Against Nephropathy in Diabetes with Atorvastatin (PANDA) randomized trial.
Soran H, Liu Y, Adam S, Siahmansur T, Ho JH, Schofield JD, Kwok S, Gittins M, France M, Younis N, Gibson JM, Durrington PN, Rutter MK. Soran H, et al. Among authors: durrington pn. J Clin Lipidol. 2018 Jan-Feb;12(1):44-55. doi: 10.1016/j.jacl.2017.10.011. Epub 2017 Nov 13. J Clin Lipidol. 2018. PMID: 29246729 Clinical Trial.
Hypercholesterolaemia and its management.
Bhatnagar D, Soran H, Durrington PN. Bhatnagar D, et al. Among authors: durrington pn. BMJ. 2008 Aug 21;337:a993. doi: 10.1136/bmj.a993. BMJ. 2008. PMID: 18719012 Review. No abstract available.
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