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Dopamine-mediated stabilization of delay-period activity in a network model of prefrontal cortex.
Durstewitz D, Seamans JK, Sejnowski TJ. Durstewitz D, et al. J Neurophysiol. 2000 Mar;83(3):1733-50. doi: 10.1152/jn.2000.83.3.1733. J Neurophysiol. 2000. PMID: 10712493
Stability could be increased by dopamine-induced enhancements of the persistent Na(+) and N-methyl-D-aspartate (NMDA) conductances. ...
Stability could be increased by dopamine-induced enhancements of the persistent Na(+) and N-methyl-D-aspartate (NMDA) conductances. . …
Dynamical basis of irregular spiking in NMDA-driven prefrontal cortex neurons.
Durstewitz D, Gabriel T. Durstewitz D, et al. Cereb Cortex. 2007 Apr;17(4):894-908. doi: 10.1093/cercor/bhk044. Epub 2006 Jun 1. Cereb Cortex. 2007. PMID: 16740581
Slow N-Methyl-D-aspartic acid (NMDA) synaptic currents are assumed to strongly contribute to the persistently elevated firing rates observed in prefrontal cortex (PFC) during working memory. ...
Slow N-Methyl-D-aspartic acid (NMDA) synaptic currents are assumed to strongly contribute to the persistently elevated firing rates o …
Hippocampal-dorsolateral prefrontal coupling as a species-conserved cognitive mechanism: a human translational imaging study.
Bähner F, Demanuele C, Schweiger J, Gerchen MF, Zamoscik V, Ueltzhöffer K, Hahn T, Meyer P, Flor H, Durstewitz D, Tost H, Kirsch P, Plichta MM, Meyer-Lindenberg A. Bähner F, et al. Neuropsychopharmacology. 2015 Jun;40(7):1674-81. doi: 10.1038/npp.2015.13. Epub 2015 Jan 12. Neuropsychopharmacology. 2015. PMID: 25578799 Free PMC article.
Amphetamine Exerts Dose-Dependent Changes in Prefrontal Cortex Attractor Dynamics during Working Memory.
Lapish CC, Balaguer-Ballester E, Seamans JK, Phillips AG, Durstewitz D. Lapish CC, et al. J Neurosci. 2015 Jul 15;35(28):10172-87. doi: 10.1523/JNEUROSCI.2421-14.2015. J Neurosci. 2015. PMID: 26180194 Free PMC article.
The present study used a combination of advanced multivariate statistical, time series analysis, and machine learning methods to assess dynamic changes in network activity from multiple single-unit recordings from the medial prefrontal cortex (mPFC) of rats while the animals perf …
The present study used a combination of advanced multivariate statistical, time series analysis, and machine learning methods to assess dyna …
Beyond bistability: biophysics and temporal dynamics of working memory.
Durstewitz D, Seamans JK. Durstewitz D, et al. Neuroscience. 2006 Apr 28;139(1):119-33. doi: 10.1016/j.neuroscience.2005.06.094. Epub 2005 Dec 2. Neuroscience. 2006. PMID: 16326020 Review.
A few important points about dopamine's role in neural network dynamics.
Durstewitz D. Durstewitz D. Pharmacopsychiatry. 2006 Feb;39 Suppl 1:S72-5. doi: 10.1055/s-2006-931499. Pharmacopsychiatry. 2006. PMID: 16508901
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