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Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells.
Dyachok O, Isakov Y, Sågetorp J, Tengholm A. Dyachok O, et al. Nature. 2006 Jan 19;439(7074):349-52. doi: 10.1038/nature04410. Nature. 2006. PMID: 16421574
Ca2+ and cAMP signaling in human embryonic stem cell-derived dopamine neurons.
Malmersjö S, Liste I, Dyachok O, Tengholm A, Arenas E, Uhlén P. Malmersjö S, et al. Among authors: dyachok o. Stem Cells Dev. 2010 Sep;19(9):1355-64. doi: 10.1089/scd.2009.0436. Stem Cells Dev. 2010. PMID: 20043754
Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets.
Alenkvist I, Dyachok O, Tian G, Li J, Mehrabanfar S, Jin Y, Birnir B, Tengholm A, Welsh M. Alenkvist I, et al. Among authors: dyachok o. J Endocrinol. 2014 Dec;223(3):267-75. doi: 10.1530/JOE-14-0531. Epub 2014 Oct 1. J Endocrinol. 2014. PMID: 25274988
CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion.
Abels M, Riva M, Bennet H, Ahlqvist E, Dyachok O, Nagaraj V, Shcherbina L, Fred RG, Poon W, Sörhede-Winzell M, Fadista J, Lindqvist A, Kask L, Sathanoori R, Dekker-Nitert M, Kuhar MJ, Ahrén B, Wollheim CB, Hansson O, Tengholm A, Fex M, Renström E, Groop L, Lyssenko V, Wierup N. Abels M, et al. Among authors: dyachok o. Diabetologia. 2016 Sep;59(9):1928-37. doi: 10.1007/s00125-016-4020-6. Epub 2016 Jun 23. Diabetologia. 2016. PMID: 27338624
Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion.
Dyachok O, Idevall-Hagren O, Sågetorp J, Tian G, Wuttke A, Arrieumerlou C, Akusjärvi G, Gylfe E, Tengholm A. Dyachok O, et al. Cell Metab. 2008 Jul;8(1):26-37. doi: 10.1016/j.cmet.2008.06.003. Cell Metab. 2008. PMID: 18590690 Free article.
Feedback activation of phospholipase C via intracellular mobilization and store-operated influx of Ca2+ in insulin-secreting beta-cells.
Thore S, Dyachok O, Gylfe E, Tengholm A. Thore S, et al. Among authors: dyachok o. J Cell Sci. 2005 Oct 1;118(Pt 19):4463-71. doi: 10.1242/jcs.02577. Epub 2005 Sep 13. J Cell Sci. 2005. PMID: 16159958
Ca(2+)-induced Ca(2+) release via inositol 1,4,5-trisphosphate receptors is amplified by protein kinase A and triggers exocytosis in pancreatic beta-cells.
Dyachok O, Gylfe E. Dyachok O, et al. J Biol Chem. 2004 Oct 29;279(44):45455-61. doi: 10.1074/jbc.M407673200. Epub 2004 Aug 16. J Biol Chem. 2004. PMID: 15316011
Oscillations of phospholipase C activity triggered by depolarization and Ca2+ influx in insulin-secreting cells.
Thore S, Dyachok O, Tengholm A. Thore S, et al. Among authors: dyachok o. J Biol Chem. 2004 May 7;279(19):19396-400. doi: 10.1074/jbc.C400088200. Epub 2004 Mar 25. J Biol Chem. 2004. PMID: 15044448
Ca2+-induced Ca2+ release by activation of inositol 1,4,5-trisphosphate receptors in primary pancreatic beta-cells.
Dyachok O, Tufveson G, Gylfe E. Dyachok O, et al. Cell Calcium. 2004 Jul;36(1):1-9. doi: 10.1016/j.ceca.2003.11.004. Cell Calcium. 2004. PMID: 15126051
Functional differences between aggregated and dispersed insulin-producing cells.
Chowdhury A, Dyachok O, Tengholm A, Sandler S, Bergsten P. Chowdhury A, et al. Among authors: dyachok o. Diabetologia. 2013 Jul;56(7):1557-68. doi: 10.1007/s00125-013-2903-3. Epub 2013 Apr 19. Diabetologia. 2013. PMID: 23604550 Free PMC article.
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