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Year Number of Results
2001 1
2003 1
2004 1
2005 1
2011 1
2012 2
2013 1
2014 2
2015 1
2018 2
2019 1
2021 3
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Dynamics of caspase-3 activation and inhibition in embryonic micromasses evaluated by a photon-counting chemiluminescence approach.
Chlastakova I, Liskova M, Kudelova J, Dubska L, Kleparnik K, Matalova E. Chlastakova I, et al. In Vitro Cell Dev Biol Anim. 2012 Oct;48(9):545-9. doi: 10.1007/s11626-012-9542-8. Epub 2012 Sep 14. In Vitro Cell Dev Biol Anim. 2012. PMID: 22976371
Two parameters of caspase-3 FMK inhibitor were investigated: first, the stability of the inhibitory potential in the time course of cultivation and, simultaneously, the dynamics of caspase-3 FMK inhibition after camptothecin-induced apopt …
Two parameters of caspase-3 FMK inhibitor were investigated: first, the stability of the inhibitory potential in the time cour …
Inhibition of autophagy enhances the anticancer activity of silver nanoparticles.
Lin J, Huang Z, Wu H, Zhou W, Jin P, Wei P, Zhang Y, Zheng F, Zhang J, Xu J, Hu Y, Wang Y, Li Y, Gu N, Wen L. Lin J, et al. Autophagy. 2014;10(11):2006-20. doi: 10.4161/auto.36293. Autophagy. 2014. PMID: 25484080 Free PMC article.
Whether Ag NPs can induce autophagy and how it might affect the anticancer activity of Ag NPs has not been reported. Here we show that Ag NPs induced autophagy in cancer cells by activating the PtdIns3K signaling pathway. ...We further demonstrated that wortmannin, …
Whether Ag NPs can induce autophagy and how it might affect the anticancer activity of Ag NPs has not been reported. Here we show tha …
X-linked alpha-thalassemia with mental retardation is downstream of protein kinase A in the meiotic cell cycle signaling cascade in Xenopus oocytes and is dynamically regulated in response to DNA damage.
O'Shea LC, Fair T, Hensey C. O'Shea LC, et al. Biol Reprod. 2019 May 1;100(5):1238-1249. doi: 10.1093/biolre/ioz001. Biol Reprod. 2019. PMID: 30649195
The downstream activation of meiosis via protein kinase A inhibition resulted in a similar decrease in ATRX protein expression. ...This increased expression is independent of p53 protein expression in apoptotic embryos, as determined by the expression of active
The downstream activation of meiosis via protein kinase A inhibition resulted in a similar decrease in ATRX protein expression …
Apoptosis and epicardial contributions act as complementary factors in remodeling of the atrioventricular canal myocardium and atrioventricular conduction patterns in the embryonic chick heart.
Vicente Steijn R, Sedmera D, Blom NA, Jongbloed M, Kvasilova A, Nanka O. Vicente Steijn R, et al. Dev Dyn. 2018 Sep;247(9):1033-1042. doi: 10.1002/dvdy.24642. Epub 2018 Aug 28. Dev Dyn. 2018. PMID: 30152577 Free article.
RESULTS: Chicken embryonic hearts were either treated with the peptide caspase inhibitor zVAD-fmk by intrapericardial injection in ovo (ED4) or underwent epicardial inhibition (ED2.5). ...Apoptotic cells were quantified (ED5-ED7) by whole-mount LysoTracker Re …
RESULTS: Chicken embryonic hearts were either treated with the peptide caspase inhibitor zVAD-fmk by intrapericardial injectio …
Protective Effect of Manganese on Apoptosis and Mitochondrial Function of Heat-Stressed Primary Chick Embryonic Myocardial Cells.
Wang R, Shi Z, Li J, Tang D, Qin S, Guo Y. Wang R, et al. Biol Trace Elem Res. 2021 Nov 15. doi: 10.1007/s12011-021-03016-2. Online ahead of print. Biol Trace Elem Res. 2021. PMID: 34779997

The results showed that Mn restored the heat stress-induced decrease in cell viability and reduced the activities of caspase-3 (P < 0.05). The repression of the deltapsim and intracellular ATP content caused by heat stress was reversed dramatically in the

The results showed that Mn restored the heat stress-induced decrease in cell viability and reduced the activities of caspase- …
The functional genomic response of developing embryonic submandibular glands to NF-kappa B inhibition.
Melnick M, Chen H, Min Zhou Y, Jaskoll T. Melnick M, et al. BMC Dev Biol. 2001;1:15. doi: 10.1186/1471-213x-1-15. Epub 2001 Oct 25. BMC Dev Biol. 2001. PMID: 11716784 Free PMC article.
Since our prior studies suggest the importance of transcription factor NF-kappaB during embryonic submandibular salivary gland (SMG) development, we attempted to delineate the emergent dynamics of a cognate signaling network by studying the molecular patterns and ph …
Since our prior studies suggest the importance of transcription factor NF-kappaB during embryonic submandibular salivary gland (SMG) …
JNK Mediates Differentiation, Cell Polarity and Apoptosis During Amphioxus Development by Regulating Actin Cytoskeleton Dynamics and ERK Signalling.
Somorjai IML, Ehebauer MT, Escrivà H, Garcia-Fernàndez J. Somorjai IML, et al. Front Cell Dev Biol. 2021 Oct 29;9:749806. doi: 10.3389/fcell.2021.749806. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34778260 Free PMC article.
It is integral to several signalling cascades, notably downstream of non-canonical Wnt and mitogen activated protein kinase (MAPK) signalling pathways. As such, it is a key regulator of cellular behaviour and patterning during embryonic development across the animal …
It is integral to several signalling cascades, notably downstream of non-canonical Wnt and mitogen activated protein kinase (MAPK) si …
Dynamic blebbing: A bottleneck to human embryonic stem cell culture that can be overcome by Laminin-Integrin signaling.
Weng NJ, Cheung C, Talbot P. Weng NJ, et al. Stem Cell Res. 2018 Dec;33:233-246. doi: 10.1016/j.scr.2018.10.022. Epub 2018 Nov 2. Stem Cell Res. 2018. PMID: 30458343 Free PMC article.
In freshly plated hESC, dynamic and apoptotic blebbing differed in time of occurrence, bleb retraction rate, mitochondrial membrane potential, and caspase 3&7 activation. ...Inhibition of focal adhesion kinase, which is activated by b …
In freshly plated hESC, dynamic and apoptotic blebbing differed in time of occurrence, bleb retraction rate, mitochondrial membrane p …
LC3 overexpression reduces Abeta neurotoxicity through increasing alpha7nAchR expression and autophagic activity in neurons and mice.
Hung SY, Huang WP, Liou HC, Fu WM. Hung SY, et al. Neuropharmacology. 2015 Jun;93:243-51. doi: 10.1016/j.neuropharm.2015.02.003. Epub 2015 Feb 14. Neuropharmacology. 2015. PMID: 25686800
The EGFP-conjugated microtubule-associated protein 1 light chain 3 (EGFP-LC3) serves to monitor autophagic process. Extracellular beta-amyloid peptide accumulation is reported as a major cause in Alzheimer's disease (AD) pathogenesis; large numbers of autophagic vac …
The EGFP-conjugated microtubule-associated protein 1 light chain 3 (EGFP-LC3) serves to monitor autophagic process. Extracellular bet …
Differential proteome analysis of human embryonic kidney cell line (HEK-293) following mycophenolic acid treatment.
Qasim M, Rahman H, Oellerich M, Asif AR. Qasim M, et al. Proteome Sci. 2011 Sep 20;9:57. doi: 10.1186/1477-5956-9-57. Proteome Sci. 2011. PMID: 21933383 Free PMC article.
RESULTS: The proliferation assay demonstrated that therapeutic MPA concentration causes a dose dependent inhibition of HEK-293 cell proliferation. A significant apoptosis was observed after MPA treatment, as revealed by caspase 3 activity. ...Further c …
RESULTS: The proliferation assay demonstrated that therapeutic MPA concentration causes a dose dependent inhibition of HEK-293 cell p …
16 results