Copper(I)-catalysed site-selective C(sp(3))-H bond chlorination of ketones, (E)-enones and alkylbenzenes by dichloramine-T.
Jin J, Zhao Y, Kyne SH, Farshadfar K, Ariafard A, Chan PWH.
Jin J, et al. Among authors: farshadfar k.
Nat Commun. 2021 Jul 1;12(1):4065. doi: 10.1038/s41467-021-23988-y.
Nat Commun. 2021.
PMID: 34210971
Free PMC article.
Here, we present a copper(I)-catalysed synthetic method for the efficient site-selective C(sp(3))-H bond chlorination of ketones, (E)-enones and alkylbenzenes by dichloramine-T at room temperature. A key feature of the broad substrate scope is tolerance to unsaturation, wh …
Here, we present a copper(I)-catalysed synthetic method for the efficient site-selective C(sp(3))-H bond chlorination of ketones, (E) …