BHRF1, a BCL2 viral homolog, disturbs mitochondrial dynamics and stimulates mitophagy to dampen type I IFN induction.
Autophagy. 2021 Jun;17(6):1296-1315. doi: 10.1080/15548627.2020.1758416. Epub 2020 May 13.
Autophagy. 2021.
PMID: 32401605
Free PMC article.
This response is notably due to their role in the activation of interferon (IFN) signaling pathways through the activity of MAVS (mitochondrial antiviral signaling protein) present at the mitochondrial surface. Here, we report that the BHRF1 protein, a BCL2 homolog encoded …
This response is notably due to their role in the activation of interferon (IFN) signaling pathways through the activity of MAVS (mitochondr …