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2004 364
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2007 511
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2009 472
2010 543
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2012 531
2013 571
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14,287 results

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Page 1
EPO and EPO-Receptor System as Potential Actionable Mechanism for the Protection of Brain and Heart in Refractory Epilepsy and SUDEP.
Auzmendi J, Puchulu MB, Rodríguez JCG, Balaszczuk AM, Lazarowski A, Merelli A. Auzmendi J, et al. Curr Pharm Des. 2020;26(12):1356-1364. doi: 10.2174/1381612826666200219095548. Curr Pharm Des. 2020. PMID: 32072891 Review.
EPO low levels are found in the central nervous system (CNS), while EPO-R is expressed in most CNS cell types. ...In the heart, high EPO-R expression in cardiac progenitor cells appears to contribute to myocardial regeneration under EPO stimulation. .. …
EPO low levels are found in the central nervous system (CNS), while EPO-R is expressed in most CNS cell types. ...In the heart …
Epo-C12 inhibits peroxiredoxin 1 peroxidase activity.
Yoda T, Furuta M, Tsutsumi T, Ikeda S, Yukizawa S, Arai S, Morita A, Yamatoya K, Nakata K, Tomoshige S, Ohgane K, Furuyama Y, Sakaguchi K, Sugawara F, Kobayashi S, Ikekita M, Kuramochi K. Yoda T, et al. Bioorg Med Chem. 2021 Jul 1;41:116203. doi: 10.1016/j.bmc.2021.116203. Epub 2021 May 10. Bioorg Med Chem. 2021. PMID: 34015702
Epo-C12 induces apoptosis in human acute lymphoblastoid leukemia BALL-1 cells. In our previous studies, seven proteins that bind to Epo-C12 were identified by a combination of pull-down experiments using biotinylated Epo-C12 (Bio-Epo-C12) and mass spec …
Epo-C12 induces apoptosis in human acute lymphoblastoid leukemia BALL-1 cells. In our previous studies, seven proteins that bind to …
Nonrenal regulation of EPO synthesis.
Weidemann A, Johnson RS. Weidemann A, et al. Kidney Int. 2009 Apr;75(7):682-8. doi: 10.1038/ki.2008.687. Epub 2009 Jan 21. Kidney Int. 2009. PMID: 19165176 Free article. Review.
Tissue-specific expression of the EPO gene is tightly controlled, and in the adult organism the kidney produces around 90% of systemic EPO. ...Apart from classical ways of regulating renal EPO during hypoxia and anemia, novel pathways have been discovered tha …
Tissue-specific expression of the EPO gene is tightly controlled, and in the adult organism the kidney produces around 90% of systemi …
EPO-modified bone marrow MSCs alleviate asthma inflammation through enhanced mitochondrial activation and transfer by upregulating HO-1.
Zhang Y, Chen LZ, Ou-Yang HF. Zhang Y, et al. Mol Med. 2025 Sep 29;31(1):307. doi: 10.1186/s10020-025-01371-7. Mol Med. 2025. PMID: 41023810 Free PMC article.
Our previous study has highlighted the ability of erythropoietin (EPO)-modified BM-MSCs (EPO-BM-MSCs) to relieve asthmatic inflammation. Here, we elucidated whether EPO-BM-MSCs improve asthmatic phenotype by mitochondrial transfer and investigated the underly …
Our previous study has highlighted the ability of erythropoietin (EPO)-modified BM-MSCs (EPO-BM-MSCs) to relieve asthmatic inf …
Rational design of selective bispecific EPO-R/CD131 agonists.
Doiron KE, Way JC, Silver PA. Doiron KE, et al. Protein Eng Des Sel. 2025 Jan 10;38:gzaf013. doi: 10.1093/protein/gzaf013. Protein Eng Des Sel. 2025. PMID: 41206499
Erythropoietin (EPO) suppresses apoptosis and promotes survival by signaling through EPO-R/EPO-R on hematopoietic progenitors or EPO-R/CD131 on non-hematopoietic cells. ...Here, we constructed a structural model of EPO-R/CD131 and designed sever …
Erythropoietin (EPO) suppresses apoptosis and promotes survival by signaling through EPO-R/EPO-R on hematopoietic proge …
Rational design of selective bispecific EPO-R/CD131 agonists.
Doiron KE, Way JC, Silver PA. Doiron KE, et al. bioRxiv [Preprint]. 2025 Aug 26:2025.04.10.648227. doi: 10.1101/2025.04.10.648227. bioRxiv. 2025. Update in: Protein Eng Des Sel. 2025 Jan 10;38:gzaf013. doi: 10.1093/protein/gzaf013. PMID: 40909672 Free PMC article. Updated. Preprint.
Erythropoietin (EPO) suppresses apoptosis and promotes survival by signaling through EPO-R/EPO-R on hematopoietic progenitors or EPO-R/CD131 on non-hematopoietic cells. ...Here, we constructed a structural model of EPO-R/CD131 and designed sever …
Erythropoietin (EPO) suppresses apoptosis and promotes survival by signaling through EPO-R/EPO-R on hematopoietic proge …
Rethinking EPO: A Paradigm Shift in Oncology?
Ferrero JM, Mograbi B, Bouriga R, Gal J, Milano G. Ferrero JM, et al. Cancers (Basel). 2025 Dec 3;17(23):3875. doi: 10.3390/cancers17233875. Cancers (Basel). 2025. PMID: 41375075 Free PMC article.
Erythropoietin (EPO) is a hormone mainly produced by the kidney. EPO stimulates red blood cell production in response to hypoxia. ...Yet, accumulating scientific evidence knowledge has highlighted the complex interactions between EPO and tumor biology that ex …
Erythropoietin (EPO) is a hormone mainly produced by the kidney. EPO stimulates red blood cell production in response to hypox …
Are current methods of measurement of erythropoietin (EPO) in human plasma or serum adequate for the diagnosis of polycythaemia vera and the assessment of EPO deficiency?
Lindstedt G, Lundberg PA. Lindstedt G, et al. Scand J Clin Lab Invest. 1998 Oct;58(6):441-58. doi: 10.1080/00365519850186247. Scand J Clin Lab Invest. 1998. PMID: 9832336 Review.
Current methodology for the immunoassay of erythropoietin (EPO) in human plasma or serum is reviewed, with an emphasis on measurement of EPO concentrations in the low and normal ranges, analytical interference and blood sampling requirements. ...It is concluded that …
Current methodology for the immunoassay of erythropoietin (EPO) in human plasma or serum is reviewed, with an emphasis on measurement …
To give or not to give recombinant EPO to anemia endangered cancer patients.
Sulkowska M, Wincewicz A, Chabowska A, Kanczuga-Koda L, Szymanska M, Koda M, Witkowska E, Sulkowski S. Sulkowska M, et al. Prague Med Rep. 2006;107(3):281-9. Prague Med Rep. 2006. PMID: 17385400 Review.
The main task concerning EPO for oncologists is the choice to give or not to give recombinant EPO to anemia endangered cancer patients. ...Nevertheless, EPO therapy shortens survival of patients in some cancers, in which antiapoptotic effect of EPO pre …
The main task concerning EPO for oncologists is the choice to give or not to give recombinant EPO to anemia endangered cancer …
Erythropoietin-mediated protection in kidney transplantation: nonerythropoietic EPO derivatives improve function without increasing risk of cardiovascular events.
van Rijt WG, van Goor H, Ploeg RJ, Leuvenink HG. van Rijt WG, et al. Transpl Int. 2014 Mar;27(3):241-8. doi: 10.1111/tri.12174. Epub 2013 Aug 22. Transpl Int. 2014. PMID: 23964738 Free article. Review.
In preclinical models, nonerythropoietic EPO derivatives, such as carbamoylated EPO and ARA290, have been tested. These EPO derivatives improve renal function and do not affect erythropoiesis. Therefore, nonerythropoietic EPO derivatives may be able to …
In preclinical models, nonerythropoietic EPO derivatives, such as carbamoylated EPO and ARA290, have been tested. These EPO …
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