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2019 3
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Early Development Challenges for Drug Products Containing Nanomaterials.
Grossman JH, Crist RM, Clogston JD. Grossman JH, et al. AAPS J. 2017 Jan;19(1):92-102. doi: 10.1208/s12248-016-9980-4. Epub 2016 Sep 9. AAPS J. 2017. PMID: 27612680
The vast majority of drug product candidates in early development fail to progress to clinics. This is true for products containing nanomaterials just as for other types of pharmaceuticals. ...
The vast majority of drug product candidates in early development fail to progress to clinics. This is true for …
Recent Findings on Nanotechnology-based Therapeutic Strategies Against Hepatocellular Carcinoma.
Samie HAA, Saeed M, Faisal SM, Kausar MA, Kamal MA. Samie HAA, et al. Curr Drug Metab. 2019;20(4):283-291. doi: 10.2174/1389200220666190308134351. Curr Drug Metab. 2019. PMID: 30854953 Review.
Besides, nanotechnology based therapeutics holds remarkable potential as an effective drug delivery system. We critically highlight the recent findings on nanotechnology mediated therapeutics strategies to combat hepatocellular carcinoma and discuss how nanotechnology plat …
Besides, nanotechnology based therapeutics holds remarkable potential as an effective drug delivery system. We critically highlight t …
Renal Clearable Luminescent Gold Nanoparticles: From the Bench to the Clinic.
Yu M, Xu J, Zheng J. Yu M, et al. Angew Chem Int Ed Engl. 2019 Mar 22;58(13):4112-4128. doi: 10.1002/anie.201807847. Epub 2019 Jan 14. Angew Chem Int Ed Engl. 2019. PMID: 30182529 Free PMC article. Review.
With more and more engineered nanoparticles (NPs) being translated to the clinic, the United States Food and Drug Administration (FDA) has recently issued the latest draft guidance on nanomaterial-containing drug products with an emphasis on und …
With more and more engineered nanoparticles (NPs) being translated to the clinic, the United States Food and Drug Administration (FDA …
Theranostic nanoparticles engineered for clinic and pharmaceutics.
Ma X, Zhao Y, Liang XJ. Ma X, et al. Acc Chem Res. 2011 Oct 18;44(10):1114-22. doi: 10.1021/ar2000056. Epub 2011 Jul 6. Acc Chem Res. 2011. PMID: 21732606 Review.
Many of these novel nanoparticles contain both drug(s) and imaging agent(s) within an individual nanoparticle for simultaneous disease diagnosis and therapy. ...In this Account, we describe the development of theranostic nanomaterials wit …
Many of these novel nanoparticles contain both drug(s) and imaging agent(s) within an individual nanoparticle fo …
Use of nanotechnology for infectious disease diagnostics: application in drug resistant tuberculosis.
Karunaratne RE, Wijenayaka LA, Wijesundera SS, De Silva KMN, Adikaram CP, Perera J. Karunaratne RE, et al. BMC Infect Dis. 2019 Jul 12;19(1):618. doi: 10.1186/s12879-019-4259-x. BMC Infect Dis. 2019. PMID: 31299893 Free PMC article.
Resistance to INH may lead to development of MDR TB. Therefore, early detection of INH resistance is important to curb spread of resistance. Due to the limited availability of rapid molecular methods for detection of drug resistance in Sri Lanka, this study w …
Resistance to INH may lead to development of MDR TB. Therefore, early detection of INH resistance is important to curb spread …