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High-throughput single-cell DNA sequencing of acute myeloid leukemia tumors with droplet microfluidics.
Pellegrino M, Sciambi A, Treusch S, Durruthy-Durruthy R, Gokhale K, Jacob J, Chen TX, Geis JA, Oldham W, Matthews J, Kantarjian H, Futreal PA, Patel K, Jones KW, Takahashi K, Eastburn DJ. Pellegrino M, et al. Among authors: eastburn dj. Genome Res. 2018 Sep;28(9):1345-1352. doi: 10.1101/gr.232272.117. Epub 2018 Aug 7. Genome Res. 2018. PMID: 30087104 Free PMC article.
Microfluidic droplet enrichment for targeted sequencing.
Eastburn DJ, Huang Y, Pellegrino M, Sciambi A, Ptáček LJ, Abate AR. Eastburn DJ, et al. Nucleic Acids Res. 2015 Jul 27;43(13):e86. doi: 10.1093/nar/gkv297. Epub 2015 Apr 14. Nucleic Acids Res. 2015. PMID: 25873629 Free PMC article.
Electrode-free picoinjection of microfluidic drops.
O'Donovan B, Eastburn DJ, Abate AR. O'Donovan B, et al. Among authors: eastburn dj. Lab Chip. 2012 Oct 21;12(20):4029-32. doi: 10.1039/c2lc40693d. Lab Chip. 2012. PMID: 22930333
Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia.
McMahon CM, Ferng T, Canaani J, Wang ES, Morrissette JJD, Eastburn DJ, Pellegrino M, Durruthy-Durruthy R, Watt CD, Asthana S, Lasater EA, DeFilippis R, Peretz CAC, McGary LHF, Deihimi S, Logan AC, Luger SM, Shah NP, Carroll M, Smith CC, Perl AE. McMahon CM, et al. Among authors: eastburn dj. Cancer Discov. 2019 Aug;9(8):1050-1063. doi: 10.1158/2159-8290.CD-18-1453. Epub 2019 May 14. Cancer Discov. 2019. PMID: 31088841 Free article.
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