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IRS-1: auditing the effectiveness of mTOR inhibitors.
Easton JB, Kurmasheva RT, Houghton PJ. Easton JB, et al. Cancer Cell. 2006 Mar;9(3):153-5. doi: 10.1016/j.ccr.2006.02.027. Cancer Cell. 2006. PMID: 16530700 Free article. Review.
Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2.
Gururajan R, Lahti JM, Grenet J, Easton J, Gruber I, Ambros PF, Kidd VJ. Gururajan R, et al. Genome Res. 1998 Sep;8(9):929-39. doi: 10.1101/gr.8.9.929. Genome Res. 1998. PMID: 9750192 Free PMC article.
Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.
Thimmaiah KN, Easton J, Huang S, Veverka KA, Germain GS, Harwood FC, Houghton PJ. Thimmaiah KN, et al. Cancer Res. 2003 Jan 15;63(2):364-74. Cancer Res. 2003. PMID: 12543789
Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity.
Huang S, Shu L, Easton J, Harwood FC, Germain GS, Ichijo H, Houghton PJ. Huang S, et al. J Biol Chem. 2004 Aug 27;279(35):36490-6. doi: 10.1074/jbc.M401208200. Epub 2004 Jun 24. J Biol Chem. 2004. PMID: 15218033
Therapeutic potential of target of rapamycin inhibitors.
Easton JB, Houghton PJ. Easton JB, et al. Expert Opin Ther Targets. 2004 Dec;8(6):551-64. doi: 10.1517/14728222.8.6.551. Expert Opin Ther Targets. 2004. PMID: 15584862 Review.
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