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Prediction of Alzheimer's disease progression within 6 years using speech: A novel approach leveraging language models.
Amini S, Hao B, Yang J, Karjadi C, Kolachalama VB, Au R, Paschalidis IC. Amini S, et al. Alzheimers Dement. 2024 Aug;20(8):5262-5270. doi: 10.1002/alz.13886. Epub 2024 Jun 25. Alzheimers Dement. 2024. PMID: 38924662 Free PMC article.
INTRODUCTION: Identification of individuals with mild cognitive impairment (MCI) who are at risk of developing Alzheimer's disease (AD) is crucial for early intervention and selection of clinical trials. ...HIGHLIGHTS: Voice record …
INTRODUCTION: Identification of individuals with mild cognitive impairment (MCI) who are at risk of developing Alzhe …
Easy Screening for Mild Alzheimer's Disease and Mild Cognitive Impairment from Elderly Speech.
Kato S, Homma A, Sakuma T. Kato S, et al. Curr Alzheimer Res. 2018;15(2):104-110. doi: 10.2174/1567205014666171120144343. Curr Alzheimer Res. 2018. PMID: 29165082
OBJECTIVE: This study presents a novel approach for early detection of cognitive impairment in the elderly. The approach incorporates the use of speech sound analysis, multivariate statistics, and data-mining techniques. We have developed …
OBJECTIVE: This study presents a novel approach for early detection of cognitive impairment in the elderly …
Speech pause and speech rate for evaluating Alzheimer's and mild cognitive impairment: A meta-analysis.
Cohen AS, Divers R, Calamia M, Masucci M, Granrud OE, Corporandy A, Warren KK, Elvevåg B, Chandler C, Diaz-Asper C. Cohen AS, et al. J Int Neuropsychol Soc. 2026 Jan;32(1):24-31. doi: 10.1017/S1355617725101677. Epub 2025 Dec 11. J Int Neuropsychol Soc. 2026. PMID: 41378466
OBJECTIVE: Evaluating pauses in natural speech is a promising strategy for improving reliability, validity, and efficiency in assessing cognitive functions in people with mild cognitive impairment (MCI) and Alzheimer's dementia (AD …
OBJECTIVE: Evaluating pauses in natural speech is a promising strategy for improving reliability, validity, and efficiency in assessi …
Digital detection of Alzheimer's disease using smiles and conversations with a chatbot.
Takeshige-Amano H, Oyama G, Ogawa M, Fusegi K, Kambe T, Shiina K, Ueno SI, Okuzumi A, Hatano T, Motoi Y, Kawakami I, Ando M, Nakayama S, Ishida Y, Maei S, Lu X, Kobayashi T, Wooden R, Ota S, Morito K, Ito Y, Nakajima Y, Yoritaka A, Kato T, Hattori N. Takeshige-Amano H, et al. Sci Rep. 2024 Nov 1;14(1):26309. doi: 10.1038/s41598-024-77220-0. Sci Rep. 2024. PMID: 39487204 Free PMC article.
Facial and speech features have been tried as cost-effective biomarkers of dementia including Alzheimer's disease (AD). ...Smile images and visual and auditory data of natural conversations with a chatbot from 99 healthy controls (HCs) and 93 individua …
Facial and speech features have been tried as cost-effective biomarkers of dementia including Alzheimer's disease …
Decreased hemodynamic response in inferior frontotemporal regions in elderly with mild cognitive impairment.
Katzorke A, Zeller JBM, Müller LD, Lauer M, Polak T, Deckert J, Herrmann MJ. Katzorke A, et al. Psychiatry Res Neuroimaging. 2018 Apr 30;274:11-18. doi: 10.1016/j.pscychresns.2018.02.003. Epub 2018 Feb 11. Psychiatry Res Neuroimaging. 2018. PMID: 29472145
The verbal fluency task (VFT) is a well-established cognitive marker for mild cognitive impairment (MCI) in the prodromal stage of Alzheimers dementia (AD). ...Therefore the aim of this study is to measure the hemodynamic response during VFT in patient …
The verbal fluency task (VFT) is a well-established cognitive marker for mild cognitive impairment (MCI) in the …
The utility of simple questions to evaluate cognitive impairment.
Daté Y, Sugiyama D, Tabuchi H, Saito N, Konishi M, Eguchi Y, Momota Y, Yoshizaki T, Mashima K, Mimura M, Nakahara J, Ito D. Daté Y, et al. PLoS One. 2020 May 14;15(5):e0233225. doi: 10.1371/journal.pone.0233225. eCollection 2020. PLoS One. 2020. PMID: 32407392 Free PMC article.
PARTICIPANTS: We enrolled 162 consecutive cases (44 cognitive normal (CN), 55 amnestic mild cognitive impairment (aMCI), and 48 Alzheimer's disease (AD)). ...CONCLUSIONS: The combination of (C- and N-) is as powerful as (AW and HTS …
PARTICIPANTS: We enrolled 162 consecutive cases (44 cognitive normal (CN), 55 amnestic mild cognitive impairment …