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Sulforaphane is not an effective antagonist of the human pregnane X-receptor in vivo.
Poulton EJ, Levy L, Lampe JW, Shen DD, Tracy J, Shuhart MC, Thummel KE, Eaton DL. Poulton EJ, et al. Among authors: eaton dl. Toxicol Appl Pharmacol. 2013 Jan 1;266(1):122-31. doi: 10.1016/j.taap.2012.10.029. Epub 2012 Nov 12. Toxicol Appl Pharmacol. 2013. PMID: 23153560 Free PMC article. Clinical Trial.
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