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Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling.
Oncotarget. 2017 Aug 27;8(41):69264-69280. doi: 10.18632/oncotarget.20566. eCollection 2017 Sep 19.
Oncotarget. 2017.
PMID: 29050202
Free PMC article.
Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity.
Li N, Lee K, Xi Y, Zhu B, Gary BD, Ramírez-Alcántara V, Gurpinar E, Canzoneri JC, Fajardo A, Sigler S, Piazza JT, Chen X, Andrews J, Thomas M, Lu W, Li Y, Laan DJ, Moyer MP, Russo S, Eberhardt BT, Yet L, Keeton AB, Grizzle WE, Piazza GA.
Li N, et al. Among authors: eberhardt bt.
Oncogene. 2015 Mar 19;34(12):1499-509. doi: 10.1038/onc.2014.94. Epub 2014 Apr 7.
Oncogene. 2015.
PMID: 24704829
Free PMC article.
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