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129 results
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Structural insights into the molecular mechanism of vitamin D receptor activation by lithocholic acid involving a new mode of ligand recognition.
Belorusova AY, Eberhardt J, Potier N, Stote RH, Dejaegere A, Rochel N. Belorusova AY, et al. Among authors: eberhardt j. J Med Chem. 2014 Jun 12;57(11):4710-9. doi: 10.1021/jm5002524. Epub 2014 May 21. J Med Chem. 2014. PMID: 24818857
Unrolr: Structural analysis of protein conformations using stochastic proximity embedding.
Eberhardt J, Stote RH, Dejaegere A. Eberhardt J, et al. J Comput Chem. 2018 Nov 15;39(30):2551-2557. doi: 10.1002/jcc.25599. J Comput Chem. 2018. PMID: 30447084
Structural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPARγ Drug Pioglitazone.
Mosure SA, Shang J, Eberhardt J, Brust R, Zheng J, Griffin PR, Forli S, Kojetin DJ. Mosure SA, et al. Among authors: eberhardt j. J Med Chem. 2019 Feb 28;62(4):2008-2023. doi: 10.1021/acs.jmedchem.8b01573. Epub 2019 Feb 7. J Med Chem. 2019. PMID: 30676741 Free PMC article.
A revisited version of the apo structure of the ligand-binding domain of the human nuclear receptor retinoic X receptor α.
Eberhardt J, McEwen AG, Bourguet W, Moras D, Dejaegere A. Eberhardt J, et al. Acta Crystallogr F Struct Biol Commun. 2019 Feb 1;75(Pt 2):98-104. doi: 10.1107/S2053230X18018022. Epub 2019 Jan 23. Acta Crystallogr F Struct Biol Commun. 2019. PMID: 30713160 Free PMC article.
Humanized GPIbα-von Willebrand factor interaction in the mouse.
Kanaji S, Orje JN, Kanaji T, Kamikubo Y, Morodomi Y, Chen Y, Zarpellon A, Eberhardt J, Forli S, Fahs SA, Sood R, Haberichter SL, Montgomery RR, Ruggeri ZM. Kanaji S, et al. Among authors: eberhardt j. Blood Adv. 2018 Oct 9;2(19):2522-2532. doi: 10.1182/bloodadvances.2018023507. Blood Adv. 2018. PMID: 30287479 Free PMC article.
Allostery in Its Many Disguises: From Theory to Applications.
Wodak SJ, Paci E, Dokholyan NV, Berezovsky IN, Horovitz A, Li J, Hilser VJ, Bahar I, Karanicolas J, Stock G, Hamm P, Stote RH, Eberhardt J, Chebaro Y, Dejaegere A, Cecchini M, Changeux JP, Bolhuis PG, Vreede J, Faccioli P, Orioli S, Ravasio R, Yan L, Brito C, Wyart M, Gkeka P, Rivalta I, Palermo G, McCammon JA, Panecka-Hofman J, Wade RC, Di Pizio A, Niv MY, Nussinov R, Tsai CJ, Jang H, Padhorny D, Kozakov D, McLeish T. Wodak SJ, et al. Among authors: eberhardt j. Structure. 2019 Apr 2;27(4):566-578. doi: 10.1016/j.str.2019.01.003. Epub 2019 Feb 7. Structure. 2019. PMID: 30744993 Free PMC article. Review.
Discovery of small-molecule enzyme activators by activity-based protein profiling.
Kok BP, Ghimire S, Kim W, Chatterjee S, Johns T, Kitamura S, Eberhardt J, Ogasawara D, Xu J, Sukiasyan A, Kim SM, Godio C, Bittencourt JM, Cameron M, Galmozzi A, Forli S, Wolan DW, Cravatt BF, Boger DL, Saez E. Kok BP, et al. Among authors: eberhardt j. Nat Chem Biol. 2020 Sep;16(9):997-1005. doi: 10.1038/s41589-020-0555-4. Epub 2020 Jun 8. Nat Chem Biol. 2020. PMID: 32514184 Free PMC article.
Alcohol decreases intestinal ratio of Lactobacillus to Enterobacteriaceae and induces hepatic immune tolerance in a murine model of DSS-colitis.
Kuprys PV, Cannon AR, Shieh J, Iftekhar N, Park SK, Eberhardt JM, Ding X, Choudhry MA. Kuprys PV, et al. Among authors: eberhardt jm. Gut Microbes. 2020 Nov 9;12(1):1-16. doi: 10.1080/19490976.2020.1838236. Gut Microbes. 2020. PMID: 33180663 Free PMC article.
The development of race effects in face processing from childhood through adulthood: Neural and behavioral evidence.
Golarai G, Ghahremani DG, Greenwood AC, Gabrieli JDE, Eberhardt JL. Golarai G, et al. Among authors: eberhardt jl. Dev Sci. 2020 Nov 5:e13058. doi: 10.1111/desc.13058. Online ahead of print. Dev Sci. 2020. PMID: 33151616
Challenges and issues of SARS-CoV-2 pool testing.
Eberhardt JN, Breuckmann NP, Eberhardt CS. Eberhardt JN, et al. Lancet Infect Dis. 2020 Nov;20(11):1233-1234. doi: 10.1016/S1473-3099(20)30467-9. Epub 2020 Jul 14. Lancet Infect Dis. 2020. PMID: 32679088 No abstract available.
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