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Desensitization of melanoma cells to autocrine TGF-beta isoforms.
Krasagakis K, Krüger-Krasagakes S, Fimmel S, Eberle J, Thölke D, von der Ohe M, Mansmann U, Orfanos CE. Krasagakis K, et al. J Cell Physiol. 1999 Feb;178(2):179-87. doi: 10.1002/(SICI)1097-4652(199902)178:2<179::AID-JCP7>3.0.CO;2-5. J Cell Physiol. 1999. PMID: 10048582
Resistance to CD95/Fas-induced and ceramide-mediated apoptosis of human melanoma cells is caused by a defective mitochondrial cytochrome c release.
Raisova M, Bektas M, Wieder T, Daniel P, Eberle J, Orfanos CE, Geilen CC. Raisova M, et al. FEBS Lett. 2000 May 4;473(1):27-32. doi: 10.1016/s0014-5793(00)01491-5. FEBS Lett. 2000. PMID: 10802053
The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis.
Raisova M, Hossini AM, Eberle J, Riebeling C, Wieder T, Sturm I, Daniel PT, Orfanos CE, Geilen CC. Raisova M, et al. J Invest Dermatol. 2001 Aug;117(2):333-40. doi: 10.1046/j.0022-202x.2001.01409.x. J Invest Dermatol. 2001. PMID: 11511312
Bcl-2 overexpression prevents apoptosis induced by ceramidase inhibitors in malignant melanoma and HaCaT keratinocytes.
Raisova M, Goltz G, Bektas M, Bielawska A, Riebeling C, Hossini AM, Eberle J, Hannun YA, Orfanos CE, Geilen CC. Raisova M, et al. FEBS Lett. 2002 Apr 10;516(1-3):47-52. doi: 10.1016/s0014-5793(02)02472-9. FEBS Lett. 2002. PMID: 11959101
Inducible nitric oxide synthase is expressed in normal human melanocytes but not in melanoma cells in response to tumor necrosis factor-alpha, interferon-gamma, and lipopolysaccharide.
Fecker LF, Eberle J, Orfanos CE, Geilen CC. Fecker LF, et al. J Invest Dermatol. 2002 Jun;118(6):1019-25. doi: 10.1046/j.1523-1747.2002.01744.x. J Invest Dermatol. 2002. PMID: 12060397
Endothelin-1 decreases basic apoptotic rates in human melanoma cell lines.
Eberle J, Fecker LF, Orfanos CE, Geilen CC. Eberle J, et al. J Invest Dermatol. 2002 Sep;119(3):549-55. doi: 10.1046/j.1523-1747.2002.01848.x. J Invest Dermatol. 2002. PMID: 12230494
The role of nuclear factor-kappa B and melanogenesis in tumor necrosis factor-alpha-induced apoptosis of normal human melanocytes.
Shang J, Eberle J, Geilen CC, Hossini AM, Fecker LF, Orfanos CE, Tebbe B. Shang J, et al. Skin Pharmacol Appl Skin Physiol. 2002 Sep-Oct;15(5):321-9. doi: 10.1159/000064536. Skin Pharmacol Appl Skin Physiol. 2002. PMID: 12239426
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