Eckert KA - Search Results

1

The human gastric cancer-associated DNA polymerase β variant D160N is a mutator that induces cellular transformation.

Donigan KA, Hile SE, Eckert KA, Sweasy JB. Donigan KA, et al. Among authors: eckert ka. DNA Repair (Amst). 2012 Apr 1;11(4):381-90. doi: 10.1016/j.dnarep.2012.01.004. Epub 2012 Feb 15. DNA Repair (Amst). 2012. PMID: 22341651 Free PMC article.

2

Prostate-cancer-associated I260M variant of DNA polymerase beta is a sequence-specific mutator.

Dalal S, Hile S, Eckert KA, Sun KW, Starcevic D, Sweasy JB. Dalal S, et al. Among authors: eckert ka. Biochemistry. 2005 Dec 6;44(48):15664-73. doi: 10.1021/bi051179z. Biochemistry. 2005. PMID: 16313169

3

DNA polymerases and human diseases.

Sweasy JB, Lauper JM, Eckert KA. Sweasy JB, et al. Among authors: eckert ka. Radiat Res. 2006 Nov;166(5):693-714. doi: 10.1667/RR0706.1. Radiat Res. 2006. PMID: 17067213 Review.

4

Loop II of DNA polymerase beta is important for discrimination during substrate binding.

Lin GC, Jaeger J, Eckert KA, Sweasy JB. Lin GC, et al. Among authors: eckert ka. DNA Repair (Amst). 2009 Feb 1;8(2):182-9. doi: 10.1016/j.dnarep.2008.10.006. Epub 2008 Dec 5. DNA Repair (Amst). 2009. PMID: 19013261 Free PMC article.

5

DNA polymerases eta and kappa exchange with the polymerase delta holoenzyme to complete common fragile site synthesis.

Barnes RP, Hile SE, Lee MY, Eckert KA. Barnes RP, et al. Among authors: eckert ka. DNA Repair (Amst). 2017 Sep;57:1-11. doi: 10.1016/j.dnarep.2017.05.006. Epub 2017 Jun 3. DNA Repair (Amst). 2017. PMID: 28605669 Free PMC article.

6

The in vitro fidelity of yeast DNA polymerase δ and polymerase ε holoenzymes during dinucleotide microsatellite DNA synthesis.

Abdulovic AL, Hile SE, Kunkel TA, Eckert KA. Abdulovic AL, et al. Among authors: eckert ka. DNA Repair (Amst). 2011 May 5;10(5):497-505. doi: 10.1016/j.dnarep.2011.02.003. Epub 2011 Mar 22. DNA Repair (Amst). 2011. PMID: 21429821 Free PMC article.

7

Interplay between DNA repair and inflammation, and the link to cancer.

Kidane D, Chae WJ, Czochor J, Eckert KA, Glazer PM, Bothwell AL, Sweasy JB. Kidane D, et al. Among authors: eckert ka. Crit Rev Biochem Mol Biol. 2014 Mar-Apr;49(2):116-39. doi: 10.3109/10409238.2013.875514. Epub 2014 Jan 13. Crit Rev Biochem Mol Biol. 2014. PMID: 24410153 Free PMC article. Review.

8

Microsatellite interruptions stabilize primate genomes and exist as population-specific single nucleotide polymorphisms within individual human genomes.

Ananda G, Hile SE, Breski A, Wang Y, Kelkar Y, Makova KD, Eckert KA. Ananda G, et al. Among authors: eckert ka. PLoS Genet. 2014 Jul 17;10(7):e1004498. doi: 10.1371/journal.pgen.1004498. eCollection 2014 Jul. PLoS Genet. 2014. PMID: 25033203 Free PMC article.

9

Variation in G-quadruplex sequence and topology differentially impacts human DNA polymerase fidelity.

Stein M, Hile SE, Weissensteiner MH, Lee M, Zhang S, Kejnovský E, Kejnovská I, Makova KD, Eckert KA. Stein M, et al. Among authors: eckert ka. DNA Repair (Amst). 2022 Nov;119:103402. doi: 10.1016/j.dnarep.2022.103402. Epub 2022 Sep 9. DNA Repair (Amst). 2022. PMID: 36116264 Free PMC article.

10

Threonine 79 is a hinge residue that governs the fidelity of DNA polymerase beta by helping to position the DNA within the active site.

Maitra M, Gudzelak A Jr, Li SX, Matsumoto Y, Eckert KA, Jager J, Sweasy JB. Maitra M, et al. Among authors: eckert ka. J Biol Chem. 2002 Sep 20;277(38):35550-60. doi: 10.1074/jbc.M204953200. Epub 2002 Jul 16. J Biol Chem. 2002. PMID: 12121998 Free article.

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