Eckman CB - Search Results

1

Biochemical detection of Abeta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease.

Golde TE, Eckman CB, Younkin SG. Golde TE, et al. Among authors: eckman cb. Biochim Biophys Acta. 2000 Jul 26;1502(1):172-87. doi: 10.1016/s0925-4439(00)00043-0. Biochim Biophys Acta. 2000. PMID: 10899442 Free article. Review.

2

Amyloid beta protein starting pyroglutamate at position 3 is a major component of the amyloid deposits in the Alzheimer's disease brain.

Harigaya Y, Saido TC, Eckman CB, Prada CM, Shoji M, Younkin SG. Harigaya Y, et al. Among authors: eckman cb. Biochem Biophys Res Commun. 2000 Sep 24;276(2):422-7. doi: 10.1006/bbrc.2000.3490. Biochem Biophys Res Commun. 2000. PMID: 11027491

3

Reduction of Abeta accumulation in the Tg2576 animal model of Alzheimer's disease after oral administration of the phosphatidyl-inositol kinase inhibitor wortmannin.

Haugabook SJ, Le T, Yager D, Zenk B, Healy BM, Eckman EA, Prada C, Younkin L, Murphy P, Pinnix I, Onstead L, Sambamurti K, Golde TE, Dickson D, Younkin SG, Eckman CB. Haugabook SJ, et al. Among authors: eckman ea, eckman cb. FASEB J. 2001 Jan;15(1):16-18. doi: 10.1096/fj.00-0528fje. Epub 2000 Nov 9. FASEB J. 2001. PMID: 11099491

4

High throughput screens for the identification of compounds that alter the accumulation of the Alzheimer's amyloid beta peptide (Abeta).

Haugabook SJ, Yager DM, Eckman EA, Golde TE, Younkin SG, Eckman CB. Haugabook SJ, et al. Among authors: eckman ea, eckman cb. J Neurosci Methods. 2001 Jul 30;108(2):171-9. doi: 10.1016/s0165-0270(01)00388-0. J Neurosci Methods. 2001. PMID: 11478976

5

Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees.

Ertekin-Taner N, Graff-Radford N, Younkin LH, Eckman C, Baker M, Adamson J, Ronald J, Blangero J, Hutton M, Younkin SG. Ertekin-Taner N, et al. Science. 2000 Dec 22;290(5500):2303-4. doi: 10.1126/science.290.5500.2303. Science. 2000. PMID: 11125143

6

Heritability of plasma amyloid beta in typical late-onset Alzheimer's disease pedigrees.

Ertekin-Taner N, Graff-Radford N, Younkin LH, Eckman C, Adamson J, Schaid DJ, Blangero J, Hutton M, Younkin SG. Ertekin-Taner N, et al. Genet Epidemiol. 2001 Jul;21(1):19-30. doi: 10.1002/gepi.1015. Genet Epidemiol. 2001. PMID: 11443731

7

Decreased neprilysin immunoreactivity in Alzheimer disease, but not in pathological aging.

Wang DS, Lipton RB, Katz MJ, Davies P, Buschke H, Kuslansky G, Verghese J, Younkin SG, Eckman C, Dickson DW. Wang DS, et al. J Neuropathol Exp Neurol. 2005 May;64(5):378-85. doi: 10.1093/jnen/64.5.378. J Neuropathol Exp Neurol. 2005. PMID: 15892294

8

Abeta42 is essential for parenchymal and vascular amyloid deposition in mice.

McGowan E, Pickford F, Kim J, Onstead L, Eriksen J, Yu C, Skipper L, Murphy MP, Beard J, Das P, Jansen K, DeLucia M, Lin WL, Dolios G, Wang R, Eckman CB, Dickson DW, Hutton M, Hardy J, Golde T. McGowan E, et al. Among authors: eckman cb. Neuron. 2005 Jul 21;47(2):191-199. doi: 10.1016/j.neuron.2005.06.030. Neuron. 2005. PMID: 16039562 Free PMC article.

9

Physiologic and pathologic events mediated by intramembranous and juxtamembranous proteolysis.

Golde TE, Eckman CB. Golde TE, et al. Among authors: eckman cb. Sci STKE. 2003 Mar 4;2003(172):RE4. doi: 10.1126/stke.2003.172.re4. Sci STKE. 2003. PMID: 12621149 Review.

10

Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43).

Gravina SA, Ho L, Eckman CB, Long KE, Otvos L Jr, Younkin LH, Suzuki N, Younkin SG. Gravina SA, et al. Among authors: eckman cb. J Biol Chem. 1995 Mar 31;270(13):7013-6. doi: 10.1074/jbc.270.13.7013. J Biol Chem. 1995. PMID: 7706234 Free article.

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