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Jakinibs for the treatment of immune dysregulation in patients with gain-of-function signal transducer and activator of transcription 1 (STAT1) or STAT3 mutations.
Forbes LR, Vogel TP, Cooper MA, Castro-Wagner J, Schussler E, Weinacht KG, Plant AS, Su HC, Allenspach EJ, Slatter M, Abinun M, Lilic D, Cunningham-Rundles C, Eckstein O, Olbrich P, Guillerman RP, Patel NC, Demirdag YY, Zerbe C, Freeman AF, Holland SM, Szabolcs P, Gennery A, Torgerson TR, Milner JD, Leiding JW. Forbes LR, et al. Among authors: eckstein o. J Allergy Clin Immunol. 2018 Nov;142(5):1665-1669. doi: 10.1016/j.jaci.2018.07.020. Epub 2018 Aug 6. J Allergy Clin Immunol. 2018. PMID: 30092289 Free PMC article.
Genetic and mechanistic diversity in pediatric hemophagocytic lymphohistiocytosis.
Chinn IK, Eckstein OS, Peckham-Gregory EC, Goldberg BR, Forbes LR, Nicholas SK, Mace EM, Vogel TP, Abhyankar HA, Diaz MI, Heslop HE, Krance RA, Martinez CA, Nguyen TC, Bashir DA, Goldman JR, Stray-Pedersen A, Pedroza LA, Poli MC, Aldave-Becerra JC, McGhee SA, Al-Herz W, Chamdin A, Coban-Akdemir ZH, Jhangiani SN, Muzny DM, Cao TN, Hong DN, Gibbs RA, Lupski JR, Orange JS, McClain KL, Allen CE. Chinn IK, et al. Blood. 2018 Jul 5;132(1):89-100. doi: 10.1182/blood-2017-11-814244. Epub 2018 Apr 9. Blood. 2018. PMID: 29632024 Free PMC article. Clinical Trial.
Genetic errors of immunity distinguish pediatric nonmalignant lymphoproliferative disorders.
Forbes LR, Eckstein OS, Gulati N, Peckham-Gregory EC, Ozuah NW, Lubega J, El-Mallawany NK, Agrusa JE, Poli MC, Vogel TP, Chaimowitz NS, Rider NL, Mace EM, Orange JS, Caldwell JW, Aldave-Becerra JC, Jolles S, Saettini F, Chong HJ, Stray-Pedersen A, Heslop HE, Kamdar KY, Rouce RH, Muzny DM, Jhangiani SN, Gibbs RA, Coban-Akdemir ZH, Lupski JR, McClain KL, Allen CE, Chinn IK. Forbes LR, et al. J Allergy Clin Immunol. 2022 Feb;149(2):758-766. doi: 10.1016/j.jaci.2021.07.015. Epub 2021 Jul 28. J Allergy Clin Immunol. 2022. PMID: 34329649 Free PMC article.
Management of severe pulmonary Langerhans cell histiocytosis in children.
Eckstein OS, Nuchtern JG, Mallory GB, Guillerman RP, Musick MA, Barclay M, Bhatt JM, Davies P, Grundy RG, Martin A, Hilliard T, Lowis SP, Picton S, Nanduri V, Visser J, Allen CE, McClain KL. Eckstein OS, et al. Pediatr Pulmonol. 2020 Aug;55(8):2074-2081. doi: 10.1002/ppul.24822. Epub 2020 Jun 8. Pediatr Pulmonol. 2020. PMID: 32511892 Free PMC article.
Real-world treatment patterns and outcomes in patients with primary hemophagocytic lymphohistiocytosis treated with emapalumab.
Chandrakasan S, Jordan MB, Baker A, Behrens EM, Bhatla D, Chien M, Eckstein OS, Henry MM, Hermiston ML, Hinson AP, Leiding JW, Oladapo A, Patel SA, Pednekar P, Ray AK, Dávila Saldaña B, Sarangi SN, Walkovich KJ, Yee JD, Zoref-Lorenz A, Allen CE. Chandrakasan S, et al. Among authors: eckstein os. Blood Adv. 2024 May 14;8(9):2248-2258. doi: 10.1182/bloodadvances.2023012217. Blood Adv. 2024. PMID: 38429096 Free PMC article.
Emapalumab Treatment in Patients With Rheumatologic Disease-Associated Hemophagocytic Lymphohistiocytosis in the United States: A Retrospective Medical Chart Review Study.
Chandrakasan S, Allen CE, Bhatla D, Carter J, Chien M, Cooper R, Draper L, Eckstein OS, Hanna R, Hays JA, Hermiston ML, Hinson AP, Hobday PM, Isakoff MS, Jordan MB, Leiding JW, Modica R, Nakano TA, Oladapo A, Patel SA, Pednekar P, Riskalla M, Sarangi SN, Satwani P, Tandra A, Walkovich KJ, Yee JD, Zoref-Lorenz A, Behrens EM; REAL‐HLH investigators. Chandrakasan S, et al. Among authors: eckstein os. Arthritis Rheumatol. 2025 Feb;77(2):226-238. doi: 10.1002/art.42985. Epub 2024 Nov 5. Arthritis Rheumatol. 2025. PMID: 39245963 Free PMC article.
Persistent fever in a pediatric renal transplant patient: Answers.
Celebi N, Vallejo JG, Eckstein OS, Geer J, Punia JN, Elenberg E. Celebi N, et al. Pediatr Nephrol. 2019 May;34(5):825-828. doi: 10.1007/s00467-018-4130-0. Epub 2018 Dec 20. Pediatr Nephrol. 2019. PMID: 30570689 No abstract available.
35 results