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Immunotherapy Resistance by Inflammation-Induced Dedifferentiation.
Mehta A, Kim YJ, Robert L, Tsoi J, Comin-Anduix B, Berent-Maoz B, Cochran AJ, Economou JS, Tumeh PC, Puig-Saus C, Ribas A. Mehta A, et al. Among authors: economou js. Cancer Discov. 2018 Aug;8(8):935-943. doi: 10.1158/2159-8290.CD-17-1178. Epub 2018 Jun 13. Cancer Discov. 2018. PMID: 29899062 Free PMC article.
T cell receptor (TCR)-transgenic CD8 lymphocytes rendered insensitive to transforming growth factor beta (TGFβ) signaling mediate superior tumor regression in an animal model of adoptive cell therapy.
Quatromoni JG, Wang Y, Vo DD, Morris LF, Jazirehi AR, McBride W, Chatila T, Koya RC, Economou JS. Quatromoni JG, et al. Among authors: economou js. J Transl Med. 2012 Jun 19;10:127. doi: 10.1186/1479-5876-10-127. J Transl Med. 2012. PMID: 22713761 Free PMC article.
Immunomodulation by imiquimod in patients with high-risk primary melanoma.
Narayan R, Nguyen H, Bentow JJ, Moy L, Lee DK, Greger S, Haskell J, Vanchinathan V, Chang PL, Tsui S, Konishi T, Comin-Anduix B, Dauphine C, Vargas HI, Economou JS, Ribas A, Bruhn KW, Craft N. Narayan R, et al. Among authors: economou js. J Invest Dermatol. 2012 Jan;132(1):163-9. doi: 10.1038/jid.2011.247. Epub 2011 Aug 18. J Invest Dermatol. 2012. PMID: 21850019 Free PMC article. Clinical Trial.
CTLA4 blockade induces frequent tumor infiltration by activated lymphocytes regardless of clinical responses in humans.
Huang RR, Jalil J, Economou JS, Chmielowski B, Koya RC, Mok S, Sazegar H, Seja E, Villanueva A, Gomez-Navarro J, Glaspy JA, Cochran AJ, Ribas A. Huang RR, et al. Among authors: economou js. Clin Cancer Res. 2011 Jun 15;17(12):4101-9. doi: 10.1158/1078-0432.CCR-11-0407. Epub 2011 May 10. Clin Cancer Res. 2011. PMID: 21558401 Free PMC article. Clinical Trial.
Radiation enhances regulatory T cell representation.
Kachikwu EL, Iwamoto KS, Liao YP, DeMarco JJ, Agazaryan N, Economou JS, McBride WH, Schaue D. Kachikwu EL, et al. Among authors: economou js. Int J Radiat Oncol Biol Phys. 2011 Nov 15;81(4):1128-35. doi: 10.1016/j.ijrobp.2010.09.034. Epub 2010 Nov 17. Int J Radiat Oncol Biol Phys. 2011. PMID: 21093169 Free PMC article.
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