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Epithelial sodium channels (ENaC) are uniformly distributed on motile cilia in the oviduct and the respiratory airways.
Enuka Y, Hanukoglu I, Edelheit O, Vaknine H, Hanukoglu A. Enuka Y, et al. Among authors: edelheit o. Histochem Cell Biol. 2012 Mar;137(3):339-53. doi: 10.1007/s00418-011-0904-1. Epub 2011 Dec 30. Histochem Cell Biol. 2012. PMID: 22207244
Identification of the roles of conserved charged residues in the extracellular domain of an epithelial sodium channel (ENaC) subunit by alanine mutagenesis.
Edelheit O, Hanukoglu I, Dascal N, Hanukoglu A. Edelheit O, et al. Am J Physiol Renal Physiol. 2011 Apr;300(4):F887-97. doi: 10.1152/ajprenal.00648.2010. Epub 2011 Jan 5. Am J Physiol Renal Physiol. 2011. PMID: 21209000 Free article.
Conserved charged residues at the surface and interface of epithelial sodium channel subunits--roles in cell surface expression and the sodium self-inhibition response.
Edelheit O, Ben-Shahar R, Dascal N, Hanukoglu A, Hanukoglu I. Edelheit O, et al. FEBS J. 2014 Apr;281(8):2097-111. doi: 10.1111/febs.12765. Epub 2014 Mar 17. FEBS J. 2014. PMID: 24571549 Free article.
Truncated beta epithelial sodium channel (ENaC) subunits responsible for multi-system pseudohypoaldosteronism support partial activity of ENaC.
Edelheit O, Hanukoglu I, Shriki Y, Tfilin M, Dascal N, Gillis D, Hanukoglu A. Edelheit O, et al. J Steroid Biochem Mol Biol. 2010 Mar;119(1-2):84-8. doi: 10.1016/j.jsbmb.2010.01.002. Epub 2010 Jan 12. J Steroid Biochem Mol Biol. 2010. PMID: 20064610
Novel mutations in epithelial sodium channel (ENaC) subunit genes and phenotypic expression of multisystem pseudohypoaldosteronism.
Edelheit O, Hanukoglu I, Gizewska M, Kandemir N, Tenenbaum-Rakover Y, Yurdakök M, Zajaczek S, Hanukoglu A. Edelheit O, et al. Clin Endocrinol (Oxf). 2005 May;62(5):547-53. doi: 10.1111/j.1365-2265.2005.02255.x. Clin Endocrinol (Oxf). 2005. PMID: 15853823 Review.
Renin-aldosterone response, urinary Na/K ratio and growth in pseudohypoaldosteronism patients with mutations in epithelial sodium channel (ENaC) subunit genes.
Hanukoglu A, Edelheit O, Shriki Y, Gizewska M, Dascal N, Hanukoglu I. Hanukoglu A, et al. Among authors: edelheit o. J Steroid Biochem Mol Biol. 2008 Sep;111(3-5):268-74. doi: 10.1016/j.jsbmb.2008.06.013. Epub 2008 Jun 26. J Steroid Biochem Mol Biol. 2008. PMID: 18634878
Simple and efficient site-directed mutagenesis using two single-primer reactions in parallel to generate mutants for protein structure-function studies.
Edelheit O, Hanukoglu A, Hanukoglu I. Edelheit O, et al. BMC Biotechnol. 2009 Jun 30;9:61. doi: 10.1186/1472-6750-9-61. BMC Biotechnol. 2009. PMID: 19566935 Free PMC article.
Subclonal Therapy by Two EGFR TKIs Guided by Sequential Plasma Cell-free DNA in EGFR-Mutated Lung Cancer.
Peled N, Roisman LC, Miron B, Pfeffer R, Lanman RB, Ilouze M, Dvir A, Soussan-Gutman L, Barlesi F, Tarcic G, Edelheit O, Gandara D, Elkabetz Y. Peled N, et al. Among authors: edelheit o. J Thorac Oncol. 2017 Jul;12(7):e81-e84. doi: 10.1016/j.jtho.2017.02.023. Epub 2017 Mar 7. J Thorac Oncol. 2017. PMID: 28286242 Free article. No abstract available.
Revisited analysis of a SHIVA01 trial cohort using functional mutational analyses successfully predicted treatment outcome.
Kamal M, Tarcic G, Dureau S, Edelheit O, Barbash Z, Lecerf C, Morel C, Miron B, Callens C, Servant N, Bieche I, Vidne M, Le Tourneau C. Kamal M, et al. Among authors: edelheit o. Mol Oncol. 2018 May;12(5):594-601. doi: 10.1002/1878-0261.12180. Epub 2018 Mar 30. Mol Oncol. 2018. PMID: 29464843 Free PMC article. Clinical Trial.