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Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes.
Schaetzlein S, Chahwan R, Avdievich E, Roa S, Wei K, Eoff RL, Sellers RS, Clark AB, Kunkel TA, Scharff MD, Edelmann W. Schaetzlein S, et al. Among authors: edelmann w. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2470-9. doi: 10.1073/pnas.1308512110. Epub 2013 Jun 10. Proc Natl Acad Sci U S A. 2013. PMID: 23754438 Free PMC article.
Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis.
Avdievich E, Reiss C, Scherer SJ, Zhang Y, Maier SM, Jin B, Hou H Jr, Rosenwald A, Riedmiller H, Kucherlapati R, Cohen PE, Edelmann W, Kneitz B. Avdievich E, et al. Among authors: edelmann w. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4247-52. doi: 10.1073/pnas.0800276105. Epub 2008 Mar 12. Proc Natl Acad Sci U S A. 2008. PMID: 18337503 Free PMC article.
Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression.
Roa S, Avdievich E, Peled JU, Maccarthy T, Werling U, Kuang FL, Kan R, Zhao C, Bergman A, Cohen PE, Edelmann W, Scharff MD. Roa S, et al. Among authors: edelmann w. Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16248-53. doi: 10.1073/pnas.0808182105. Epub 2008 Oct 14. Proc Natl Acad Sci U S A. 2008. PMID: 18854411 Free PMC article.
Mismatch-mediated error prone repair at the immunoglobulin genes.
Chahwan R, Edelmann W, Scharff MD, Roa S. Chahwan R, et al. Among authors: edelmann w. Biomed Pharmacother. 2011 Dec;65(8):529-36. doi: 10.1016/j.biopha.2011.09.001. Epub 2011 Oct 24. Biomed Pharmacother. 2011. PMID: 22100214 Free PMC article. Review.
AIDing antibody diversity by error-prone mismatch repair.
Chahwan R, Edelmann W, Scharff MD, Roa S. Chahwan R, et al. Among authors: edelmann w. Semin Immunol. 2012 Aug;24(4):293-300. doi: 10.1016/j.smim.2012.05.005. Epub 2012 Jun 14. Semin Immunol. 2012. PMID: 22703640 Free PMC article. Review.
162 results