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Attenuation of FGF signalling in mouse beta-cells leads to diabetes.
Hart AW, Baeza N, Apelqvist A, Edlund H. Hart AW, et al. Among authors: edlund h. Nature. 2000 Dec 14;408(6814):864-8. doi: 10.1038/35048589. Nature. 2000. PMID: 11130726
Toward a renewable source of pancreatic beta-cells.
Ricordi C, Edlund H. Ricordi C, et al. Among authors: edlund h. Nat Biotechnol. 2008 Apr;26(4):397-8. doi: 10.1038/nbt0408-397. Nat Biotechnol. 2008. PMID: 18392020 No abstract available.
Retinoic acid promotes the generation of pancreatic endocrine progenitor cells and their further differentiation into beta-cells.
Oström M, Loffler KA, Edfalk S, Selander L, Dahl U, Ricordi C, Jeon J, Correa-Medina M, Diez J, Edlund H. Oström M, et al. Among authors: edlund h. PLoS One. 2008 Jul 30;3(7):e2841. doi: 10.1371/journal.pone.0002841. PLoS One. 2008. PMID: 18665267 Free PMC article.
Attenuated Wnt signaling perturbs pancreatic growth but not pancreatic function.
Papadopoulou S, Edlund H. Papadopoulou S, et al. Among authors: edlund h. Diabetes. 2005 Oct;54(10):2844-51. doi: 10.2337/diabetes.54.10.2844. Diabetes. 2005. PMID: 16186384
The anterior chamber of the eye is a transplantation site that supports and enables visualisation of beta cell development in mice.
Ali Y, Diez J, Selander L, Zheng X, Edlund H, Berggren PO. Ali Y, et al. Among authors: edlund h. Diabetologia. 2016 May;59(5):1007-11. doi: 10.1007/s00125-016-3883-x. Epub 2016 Feb 4. Diabetologia. 2016. PMID: 26847769
MFng is dispensable for mouse pancreas development and function.
Svensson P, Bergqvist I, Norlin S, Edlund H. Svensson P, et al. Among authors: edlund h. Mol Cell Biol. 2009 Apr;29(8):2129-38. doi: 10.1128/MCB.01644-08. Epub 2009 Feb 17. Mol Cell Biol. 2009. PMID: 19223466 Free PMC article.
The homeodomain-interacting protein kinase 2 regulates insulin promoter factor-1/pancreatic duodenal homeobox-1 transcriptional activity.
Boucher MJ, Simoneau M, Edlund H. Boucher MJ, et al. Among authors: edlund h. Endocrinology. 2009 Jan;150(1):87-97. doi: 10.1210/en.2007-0865. Epub 2008 Sep 4. Endocrinology. 2009. PMID: 18772243
Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion.
Edfalk S, Steneberg P, Edlund H. Edfalk S, et al. Among authors: edlund h. Diabetes. 2008 Sep;57(9):2280-7. doi: 10.2337/db08-0307. Epub 2008 Jun 2. Diabetes. 2008. PMID: 18519800 Free PMC article.
Gene array identification of Ipf1/Pdx1-/- regulated genes in pancreatic progenitor cells.
Svensson P, Williams C, Lundeberg J, Rydén P, Bergqvist I, Edlund H. Svensson P, et al. Among authors: edlund h. BMC Dev Biol. 2007 Nov 23;7:129. doi: 10.1186/1471-213X-7-129. BMC Dev Biol. 2007. PMID: 18036209 Free PMC article.
BMP4-BMPR1A signaling in beta cells is required for and augments glucose-stimulated insulin secretion.
Goulley J, Dahl U, Baeza N, Mishina Y, Edlund H. Goulley J, et al. Among authors: edlund h. Cell Metab. 2007 Mar;5(3):207-19. doi: 10.1016/j.cmet.2007.01.009. Cell Metab. 2007. PMID: 17339028
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