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Quantification of normal cell fraction and copy number neutral LOH in clinical lung cancer samples using SNP array data.
Göransson H, Edlund K, Rydåker M, Rasmussen M, Winquist J, Ekman S, Bergqvist M, Thomas A, Lambe M, Rosenquist R, Holmberg L, Micke P, Botling J, Isaksson A. Göransson H, et al. PLoS One. 2009 Jun 26;4(6):e6057. doi: 10.1371/journal.pone.0006057. PLoS One. 2009. PMID: 19557126 Free PMC article.
Gene copy number aberrations are associated with survival in histologic subgroups of non-small cell lung cancer.
Micke P, Edlund K, Holmberg L, Kultima HG, Mansouri L, Ekman S, Bergqvist M, Scheibenflug L, Lamberg K, Myrdal G, Berglund A, Andersson A, Lambe M, Nyberg F, Thomas A, Isaksson A, Botling J. Micke P, et al. J Thorac Oncol. 2011 Nov;6(11):1833-40. doi: 10.1097/JTO.0b013e3182295917. J Thorac Oncol. 2011. PMID: 22011649
CD99 is a novel prognostic stromal marker in non-small cell lung cancer.
Edlund K, Lindskog C, Saito A, Berglund A, Pontén F, Göransson-Kultima H, Isaksson A, Jirström K, Planck M, Johansson L, Lambe M, Holmberg L, Nyberg F, Ekman S, Bergqvist M, Landelius P, Lamberg K, Botling J, Ostman A, Micke P. Edlund K, et al. Int J Cancer. 2012 Nov 15;131(10):2264-73. doi: 10.1002/ijc.27518. Epub 2012 Apr 24. Int J Cancer. 2012. PMID: 22392539
Consistent mutation status within histologically heterogeneous lung cancer lesions.
Mattsson JS, Imgenberg-Kreuz J, Edlund K, Botling J, Micke P. Mattsson JS, et al. Histopathology. 2012 Oct;61(4):744-8. doi: 10.1111/j.1365-2559.2012.04245.x. Histopathology. 2012. PMID: 22458769
Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors.
Edlund K, Larsson O, Ameur A, Bunikis I, Gyllensten U, Leroy B, Sundström M, Micke P, Botling J, Soussi T. Edlund K, et al. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9551-6. doi: 10.1073/pnas.1200019109. Epub 2012 May 24. Proc Natl Acad Sci U S A. 2012. PMID: 22628563 Free PMC article.
Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis, and tissue microarray validation.
Botling J, Edlund K, Lohr M, Hellwig B, Holmberg L, Lambe M, Berglund A, Ekman S, Bergqvist M, Pontén F, König A, Fernandes O, Karlsson M, Helenius G, Karlsson C, Rahnenführer J, Hengstler JG, Micke P. Botling J, et al. Clin Cancer Res. 2013 Jan 1;19(1):194-204. doi: 10.1158/1078-0432.CCR-12-1139. Epub 2012 Oct 2. Clin Cancer Res. 2013. PMID: 23032747
The human liver-specific proteome defined by transcriptomics and antibody-based profiling.
Kampf C, Mardinoglu A, Fagerberg L, Hallström BM, Edlund K, Lundberg E, Pontén F, Nielsen J, Uhlen M. Kampf C, et al. FASEB J. 2014 Jul;28(7):2901-14. doi: 10.1096/fj.14-250555. Epub 2014 Mar 19. FASEB J. 2014. PMID: 24648543
., Edlund, K., Lundberg, E., Pontén, F., Nielsen, J., Uhlen, M. The human liver-specific proteome defined by transcriptomics and antibody-based profiling....
., Edlund, K., Lundberg, E., Pontén, F., Nielsen, J., Uhlen, M. The human liver-specific proteome defined by transcriptomics a …
Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non-small-cell lung cancer.
Micke P, Mattsson JS, Edlund K, Lohr M, Jirström K, Berglund A, Botling J, Rahnenfuehrer J, Marincevic M, Pontén F, Ekman S, Hengstler J, Wöll S, Sahin U, Türeci O. Micke P, et al. Int J Cancer. 2014 Nov 1;135(9):2206-14. doi: 10.1002/ijc.28857. Epub 2014 Apr 8. Int J Cancer. 2014. PMID: 24710653
An integrative analysis of the tumorigenic role of TAZ in human non-small cell lung cancer.
Noguchi S, Saito A, Horie M, Mikami Y, Suzuki HI, Morishita Y, Ohshima M, Abiko Y, Mattsson JS, König H, Lohr M, Edlund K, Botling J, Micke P, Nagase T. Noguchi S, et al. Clin Cancer Res. 2014 Sep 1;20(17):4660-72. doi: 10.1158/1078-0432.CCR-13-3328. Epub 2014 Jun 20. Clin Cancer Res. 2014. PMID: 24951773
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