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PASylation of IL-1 receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis.
Powers NE, Swartzwelter B, Marchetti C, de Graaf DM, Lerchner A, Schlapschy M, Datar R, Binder U, Edwards CK 3rd, Skerra A, Dinarello CA. Powers NE, et al. Among authors: edwards ck 3rd. J Biol Chem. 2020 Jan 17;295(3):868-882. doi: 10.1074/jbc.RA119.010340. Epub 2019 Dec 9. J Biol Chem. 2020. PMID: 31819009 Free PMC article.
Pyrvinium targets autophagy addiction to promote cancer cell death.
Deng L, Lei Y, Liu R, Li J, Yuan K, Li Y, Chen Y, Liu Y, Lu Y, Edwards CK 3rd, Huang C, Wei Y. Deng L, et al. Among authors: edwards ck 3rd. Cell Death Dis. 2013 May 2;4(5):e614. doi: 10.1038/cddis.2013.142. Cell Death Dis. 2013. PMID: 23640456 Free PMC article.
Combined anti-tumor necrosis factor-α therapy and DMARD therapy in rheumatoid arthritis patients reduces inflammatory gene expression in whole blood compared to DMARD therapy alone.
Edwards CK 3rd, Green JS, Volk HD, Schiff M, Kotzin BL, Mitsuya H, Kawaguchi T, Sakata KM, Cheronis J, Trollinger D, Bankaitis-Davis D, Dinarello CA, Norris DA, Bevilacqua MP, Fujita M, Burmester GR. Edwards CK 3rd, et al. Front Immunol. 2012 Dec 4;3:366. doi: 10.3389/fimmu.2012.00366. eCollection 2012. Front Immunol. 2012. PMID: 23264777 Free PMC article.
Synovial tissue rank ligand expression and radiographic progression in rheumatoid arthritis: observations from a proof-of-concept randomized clinical trial of cytokine blockade.
Rooney T, Edwards CK 3rd, Gogarty M, Greenan L, Veale DJ, FitzGerald O, Dayer JM, Bresnihan B. Rooney T, et al. Among authors: edwards ck 3rd. Rheumatol Int. 2010 Nov;30(12):1571-80. doi: 10.1007/s00296-009-1191-1. Epub 2009 Oct 22. Rheumatol Int. 2010. PMID: 19847430 Clinical Trial.
Visualizing CD4 T-cell migration into inflamed skin and its inhibition by CCR4/CCR10 blockades using in vivo imaging model.
Wang X, Fujita M, Prado R, Tousson A, Hsu HC, Schottelius A, Kelly DR, Yang PA, Wu Q, Chen J, Xu H, Elmets CA, Mountz JD, Edwards CK 3rd. Wang X, et al. Among authors: edwards ck 3rd. Br J Dermatol. 2010 Mar;162(3):487-96. doi: 10.1111/j.1365-2133.2009.09552.x. Epub 2009 Oct 15. Br J Dermatol. 2010. PMID: 19832835 Free PMC article.
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