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FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies.
Wynes MW, Hinz TK, Gao D, Martini M, Marek LA, Ware KE, Edwards MG, Böhm D, Perner S, Helfrich BA, Dziadziuszko R, Jassem J, Wojtylak S, Sejda A, Gozgit JM, Bunn PA Jr, Camidge DR, Tan AC, Hirsch FR, Heasley LE. Wynes MW, et al. Among authors: edwards mg. Clin Cancer Res. 2014 Jun 15;20(12):3299-309. doi: 10.1158/1078-0432.CCR-13-3060. Epub 2014 Apr 25. Clin Cancer Res. 2014. PMID: 24771645 Free PMC article.
Altered Cell-Cycle Control, Inflammation, and Adhesion in High-Risk Persistent Bronchial Dysplasia.
Merrick DT, Edwards MG, Franklin WA, Sugita M, Keith RL, Miller YE, Friedman MB, Dwyer-Nield LD, Tennis MA, O'Keefe MC, Donald EJ, Malloy JM, van Bokhoven A, Wilson S, Koch PJ, O'Shea C, Coldren C, Orlicky DJ, Lu X, Baron AE, Hickey G, Kennedy TC, Powell R, Heasley L, Bunn PA, Geraci M, Nemenoff RA. Merrick DT, et al. Among authors: edwards mg. Cancer Res. 2018 Sep 1;78(17):4971-4983. doi: 10.1158/0008-5472.CAN-17-3822. Epub 2018 Jul 11. Cancer Res. 2018. PMID: 29997230 Free PMC article.
Concurrent alterations in TERT, KDM6A, and the BRCA pathway in bladder cancer.
Nickerson ML, Dancik GM, Im KM, Edwards MG, Turan S, Brown J, Ruiz-Rodriguez C, Owens C, Costello JC, Guo G, Tsang SX, Li Y, Zhou Q, Cai Z, Moore LE, Lucia MS, Dean M, Theodorescu D. Nickerson ML, et al. Among authors: edwards mg. Clin Cancer Res. 2014 Sep 15;20(18):4935-48. doi: 10.1158/1078-0432.CCR-14-0330. Clin Cancer Res. 2014. PMID: 25225064 Free PMC article.
Increased cell surface Fas expression is necessary and sufficient to sensitize lung fibroblasts to Fas ligation-induced apoptosis: implications for fibroblast accumulation in idiopathic pulmonary fibrosis.
Wynes MW, Edelman BL, Kostyk AG, Edwards MG, Coldren C, Groshong SD, Cosgrove GP, Redente EF, Bamberg A, Brown KK, Reisdorph N, Keith RC, Frankel SK, Riches DW. Wynes MW, et al. Among authors: edwards mg. J Immunol. 2011 Jul 1;187(1):527-37. doi: 10.4049/jimmunol.1100447. Epub 2011 Jun 1. J Immunol. 2011. PMID: 21632719
Application of SNP microarrays to the genome-wide analysis of chromosomal instability in premalignant airway lesions.
Nakachi I, Rice JL, Coldren CD, Edwards MG, Stearman RS, Glidewell SC, Varella-Garcia M, Franklin WA, Keith RL, Lewis MT, Gao B, Merrick DT, Miller YE, Geraci MW. Nakachi I, et al. Among authors: edwards mg. Cancer Prev Res (Phila). 2014 Feb;7(2):255-65. doi: 10.1158/1940-6207.CAPR-12-0485. Epub 2013 Dec 17. Cancer Prev Res (Phila). 2014. PMID: 24346345 Free PMC article.
Peripheral blood mononuclear cell gene expression in chronic obstructive pulmonary disease.
Bahr TM, Hughes GJ, Armstrong M, Reisdorph R, Coldren CD, Edwards MG, Schnell C, Kedl R, LaFlamme DJ, Reisdorph N, Kechris KJ, Bowler RP. Bahr TM, et al. Among authors: edwards mg. Am J Respir Cell Mol Biol. 2013 Aug;49(2):316-23. doi: 10.1165/rcmb.2012-0230OC. Am J Respir Cell Mol Biol. 2013. PMID: 23590301 Free PMC article. Clinical Trial.
Novel Role for γ-Catenin in the Regulation of Cancer Cell Migration via the Induction of Hepatocyte Growth Factor Activator Inhibitor Type 1 (HAI-1).
Sechler M, Borowicz S, Van Scoyk M, Avasarala S, Zerayesus S, Edwards MG, Kumar Karuppusamy Rathinam M, Zhao X, Wu PY, Tang K, Bikkavilli RK, Winn RA. Sechler M, et al. Among authors: edwards mg. J Biol Chem. 2015 Jun 19;290(25):15610-15620. doi: 10.1074/jbc.M114.631820. Epub 2015 Apr 29. J Biol Chem. 2015. PMID: 25925948 Free PMC article.
hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression.
Avasarala S, Van Scoyk M, Wang J, Sechler M, Vandervest K, Brzezinski C, Weekes C, Edwards MG, Arcaroli J, Davis RE, Bikkavilli RK, Winn RA. Avasarala S, et al. Among authors: edwards mg. Biol Open. 2013 May 22;2(7):675-85. doi: 10.1242/bio.20134507. Print 2013 Jul 15. Biol Open. 2013. PMID: 23862015 Free PMC article.
152 results