Efficacy of metformin targets on cardiometabolic health in the general population and non-diabetic individuals: a Mendelian randomization study.
Zheng J, Xu M, Yang Q, Hu C, Walker V, Lu J, Wang J, Liu R, Xu Y, Wang T, Zhao Z, Yuan J, Burgess S, Au Yeung SL, Luo S, Anderson EL, Holmes MV, Smith GD, Ning G, Wang W, Gaunt TR, Bi Y.
Zheng J, et al.
EBioMedicine. 2023 Oct;96:104803. doi: 10.1016/j.ebiom.2023.104803. Epub 2023 Sep 19.
EBioMedicine. 2023.
PMID: 37734206
Free PMC article.
METHODS: Genetic variants close to metformin-targeted genes associated with expression of the corresponding genes and glycated haemoglobin (HbA(1c)) level were used to proxy therapeutic effects of seven metformin-related drug targets. ...One-sample MR …
METHODS: Genetic variants close to metformin-targeted genes associated with expression of the corresponding genes and g …