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Year Number of Results
1998 2
2004 1
2006 2
2007 1
2008 1
2009 1
2010 1
2012 2
2013 2
2014 3
2015 6
2016 15
2017 8
2018 6
2019 8
2020 12
2021 19
2022 2
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Effects of Dapagliflozin in Patients With Kidney Disease, With and Without Heart Failure.
McMurray JJV, Wheeler DC, Stefánsson BV, Jongs N, Postmus D, Correa-Rotter R, Chertow GM, Hou FF, Rossing P, Sjöström CD, Solomon SD, Toto RD, Langkilde AM, Heerspink HJL; DAPA-CKD Trial Committees and Investigators. McMurray JJV, et al. JACC Heart Fail. 2021 Nov;9(11):807-820. doi: 10.1016/j.jchf.2021.06.017. Epub 2021 Aug 23. JACC Heart Fail. 2021. PMID: 34446370 Free article. Clinical Trial.
OBJECTIVES: The purpose of this paper was to investigate the effects of dapagliflozin in chronic kidney disease (CKD) patients, with and without heart failure (HF). ...(A Study to Evaluate the Effect of Dapagliflozin on Renal Outcomes and Cardio …
OBJECTIVES: The purpose of this paper was to investigate the effects of dapagliflozin in chronic kidney disease (CKD) patients …
Diet-Derived Circulating Antioxidants and Risk of Coronary Heart Disease: A Mendelian Randomization Study.
Luo J, le Cessie S, van Heemst D, Noordam R. Luo J, et al. J Am Coll Cardiol. 2021 Jan 5;77(1):45-54. doi: 10.1016/j.jacc.2020.10.048. J Am Coll Cardiol. 2021. PMID: 33413940 Free article.
BACKGROUND: Previously, observational studies have identified associations between higher levels of dietary-derived antioxidants and lower risk of coronary heart disease (CHD), whereas randomized clinical trials showed no reduction in CHD ris
BACKGROUND: Previously, observational studies have identified associations between higher levels of dietary-derived antioxidants and …
Systematic Coronary Risk Evaluation (SCORE): JACC Focus Seminar 4/8.
Graham IM, Di Angelantonio E, Visseren F, De Bacquer D, Ference BA, Timmis A, Halle M, Vardas P, Huculeci R, Cooney MT; European Society of Cardiology Cardiovascular Risk Collaboration. Graham IM, et al. J Am Coll Cardiol. 2021 Jun 22;77(24):3046-3057. doi: 10.1016/j.jacc.2021.04.052. J Am Coll Cardiol. 2021. PMID: 34140109 Free PMC article. Review.
Clinical estimation of the combined effect of several risk factors is unreliable and this resulted in the development of a number of risk estimation systems to guide clinical practice. Here, after defining general principles of risk estimation, the aut …
Clinical estimation of the combined effect of several risk factors is unreliable and this resulted in the development of a num …
Exercise-Induced Ventricular Ectopy and Cardiovascular Mortality in Asymptomatic Individuals.
Refaat MM, Gharios C, Moorthy MV, Abdulhai F, Blumenthal RS, Jaffa MA, Mora S. Refaat MM, et al. J Am Coll Cardiol. 2021 Dec 7;78(23):2267-2277. doi: 10.1016/j.jacc.2021.09.1366. J Am Coll Cardiol. 2021. PMID: 34857087
After adjusting for age, sex, diabetes, hypertension, lipids, smoking, body mass index, and family history of premature coronary disease, high-grade PVCs during recovery were associated with cardiovascular mortality (hazard ratio [HR]: 1.82; 95% CI: 1.19-2.79; P = 0 …
After adjusting for age, sex, diabetes, hypertension, lipids, smoking, body mass index, and family history of premature coronary d
Effect of CYP2C19 Genotype on Ischemic Outcomes During Oral P2Y12 Inhibitor Therapy: A Meta-Analysis.
Pereira NL, Rihal C, Lennon R, Marcus G, Shrivastava S, Bell MR, So D, Geller N, Goodman SG, Hasan A, Lerman A, Rosenberg Y, Bailey K, Murad MH, Farkouh ME. Pereira NL, et al. JACC Cardiovasc Interv. 2021 Apr 12;14(7):739-750. doi: 10.1016/j.jcin.2021.01.024. Epub 2021 Mar 17. JACC Cardiovasc Interv. 2021. PMID: 33744207 Free article.
OBJECTIVES: The aim of this study was to examine the effect of CYP2C19 genotype on clinical outcomes in patients with coronary artery disease (CAD) who predominantly underwent percutaneous coronary intervention (PCI), comparing those treated wit …
OBJECTIVES: The aim of this study was to examine the effect of CYP2C19 genotype on clinical outcomes in patients with coron
Genome-wide associations for birth weight and correlations with adult disease.
Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, van Zuydam NR, Gaulton KJ, Grarup N, Bradfield JP, Strachan DP, Li-Gao R, Ahluwalia TS, Kreiner E, Rueedi R, Lyytikäinen LP, Cousminer DL, Wu Y, Thiering E, Wang CA, Have CT, Hottenga JJ, Vilor-Tejedor N, Joshi PK, Boh ETH, Ntalla I, Pitkänen N, Mahajan A, van Leeuwen EM, Joro R, Lagou V, Nodzenski M, Diver LA, Zondervan KT, Bustamante M, Marques-Vidal P, Mercader JM, Bennett AJ, Rahmioglu N, Nyholt DR, Ma RCW, Tam CHT, Tam WH; CHARGE Consortium Hematology Working Group, Ganesh SK, van Rooij FJ, Jones SE, Loh PR, Ruth KS, Tuke MA, Tyrrell J, Wood AR, Yaghootkar H, Scholtens DM, Paternoster L, Prokopenko I, Kovacs P, Atalay M, Willems SM, Panoutsopoulou K, Wang X, Carstensen L, Geller F, Schraut KE, Murcia M, van Beijsterveldt CE, Willemsen G, Appel EVR, Fonvig CE, Trier C, Tiesler CM, Standl M, Kutalik Z, Bonas-Guarch S, Hougaard DM, Sánchez F, Torrents D, Waage J, Hollegaard MV, de Haan HG, Rosendaal FR, Medina-Gomez C, Ring SM, Hemani G, McMahon G, Robertson NR, Groves CJ, Langenberg C, Luan J, Scott RA, Zhao JH, Mentch FD, MacKenzie SM, Reynolds RM; Early Growth Genetics (EGG) Consortium, Lowe WL Jr, Tönjes A, Stumvoll M, Lindi V, Lakka TA, van Duijn CM, Kiess W, Körner A, Sørensen TI, Niinikoski H, Pahkala K, Raitakari OT, Zeggini E, Dedoussis GV, Teo YY, Saw SM, Melbye M, Campbell H, Wilson JF, Vrijheid M, de Geus EJ, Boomsma DI, Kadarmideen HN, Holm JC, Hansen T, Sebert S, Hattersley AT, Beilin LJ, Newnham JP, Pennell CE, Heinrich J, Adair LS, Borja JB, Mohlke KL, Eriksson JG, Widén EE, Kähönen M, Viikari JS, Lehtimäki T, Vollenweider P, Bønnelykke K, Bisgaard H, Mook-Kanamori DO, Hofman A, Rivadeneira F, Uitterlinden AG, Pisinger C, Pedersen O, Power C, Hyppönen E, Wareham NJ, Hakonarson H, Davies E, Walker BR, Jaddoe VW, Jarvelin MR, Grant SF, Vaag AA, Lawlor DA, Frayling TM, Davey Smith G, Morris AP, Ong KK, Felix JF, Timpson NJ, Perry JR, Evans DM, McCarthy MI, Freathy RM. Horikoshi M, et al. Nature. 2016 Oct 13;538(7624):248-252. doi: 10.1038/nature19806. Epub 2016 Sep 28. Nature. 2016. PMID: 27680694 Free PMC article.
Overall, approximately 15% of variance in BW was captured by assays of fetal genetic variation. Using genetic association alone, we found strong inverse genetic correlations between BW and systolic blood pressure (R(g) = -0.22, P = 5.5 10(-13)), T2D (R(g) = - …
Overall, approximately 15% of variance in BW was captured by assays of fetal genetic variation. Using genetic association alon …
Effect of Disclosing Genetic Risk for Coronary Heart Disease on Information Seeking and Sharing: The MI-GENES Study (Myocardial Infarction Genes).
Brown SN, Jouni H, Marroush TS, Kullo IJ. Brown SN, et al. Circ Cardiovasc Genet. 2017 Aug;10(4):e001613. doi: 10.1161/CIRCGENETICS.116.001613. Circ Cardiovasc Genet. 2017. PMID: 28779015 Free PMC article.
BACKGROUND: Whether disclosing genetic risk for coronary heart disease (CHD) to individuals influences information seeking and information sharing is not known. We hypothesized that disclosing genetic
BACKGROUND: Whether disclosing genetic risk for coronary heart disease (CHD) to individuals influe …
The role of miRNAs in cardiovascular disease risk factors.
Jones Buie JN, Goodwin AJ, Cook JA, Halushka PV, Fan H. Jones Buie JN, et al. Atherosclerosis. 2016 Nov;254:271-281. doi: 10.1016/j.atherosclerosis.2016.09.067. Epub 2016 Sep 22. Atherosclerosis. 2016. PMID: 27693002 Free PMC article. Review.
Coronary artery disease and atherosclerosis are complex pathologies that develop over time due to genetic and environmental factors. Differential expression of miRNAs has been identified in patients with coronary artery disease and atheroscleros
Coronary artery disease and atherosclerosis are complex pathologies that develop over time due to genetic and environme
Lung function and cardiovascular disease: a two-sample Mendelian randomisation study.
Higbee DH, Granell R, Sanderson E, Davey Smith G, Dodd JW. Higbee DH, et al. Eur Respir J. 2021 Sep 9;58(3):2003196. doi: 10.1183/13993003.03196-2020. Print 2021 Sep. Eur Respir J. 2021. PMID: 33574079
BACKGROUND: Observational studies suggest an association between reduced lung function and risk of coronary artery disease and ischaemic stroke, independent of shared cardiovascular risk factors such as cigarette smoking. ...Reduced force …
BACKGROUND: Observational studies suggest an association between reduced lung function and risk of coronary artery d
External validation of integrated genetic-epigenetic biomarkers for predicting incident coronary heart disease.
Dogan MV, Knight S, Dogan TK, Knowlton KU, Philibert R. Dogan MV, et al. Epigenomics. 2021 Jul;13(14):1095-1112. doi: 10.2217/epi-2021-0123. Epub 2021 Jun 21. Epigenomics. 2021. PMID: 34148365
Aim: The Framingham Risk Score (FRS) and atherosclerotic cardiovascular disease (ASCVD) Pooled Cohort Equation (PCE) for predicting risk for incident coronary heart disease (CHD) work poorly. ...Conceivably, incorporating epigenetic in
Aim: The Framingham Risk Score (FRS) and atherosclerotic cardiovascular disease (ASCVD) Pooled Cohort Equation (PCE) for predi …
84 results