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Comparative efficacy and acceptability of pharmacological, psychological, and neurostimulatory interventions for ADHD in adults: a systematic review and component network meta-analysis.
Ostinelli EG, Schulze M, Zangani C, Farhat LC, Tomlinson A, Del Giovane C, Chamberlain SR, Philipsen A, Young S, Cowen PJ, Bilbow A, Cipriani A, Cortese S. Ostinelli EG, et al. Lancet Psychiatry. 2025 Jan;12(1):32-43. doi: 10.1016/S2215-0366(24)00360-2. Lancet Psychiatry. 2025. PMID: 39701638 Free article.
We aimed to address these important knowledge gaps. METHODS: In this systematic review and component network meta-analysis (NMA), we searched multiple databases for published and unpublished randomised controlled trials (RCTs) investigating pharmacolog …
We aimed to address these important knowledge gaps. METHODS: In this systematic review and component network meta-an …
Effect of psychiatric consultation models in primary care. A systematic review and meta-analysis of randomized clinical trials.
van der Feltz-Cornelis CM, Van Os TW, Van Marwijk HW, Leentjens AF. van der Feltz-Cornelis CM, et al. J Psychosom Res. 2010 Jun;68(6):521-33. doi: 10.1016/j.jpsychores.2009.10.012. Epub 2010 Jan 15. J Psychosom Res. 2010. PMID: 20488268 Review.
OBJECTIVE: Psychiatric consultation in primary care is meant to enhance and improve treatment for mental disorder in that setting. ...CONCLUSION: Psychiatric consultation in the primary care setting is effective in pa …
OBJECTIVE: Psychiatric consultation in primary care is meant to enhance and improve treatment for mental disorde …
Effect of N-methyl-D-aspartate receptor enhancing agents on cognition in dementia: an exploratory systematic review and meta-analysis of randomized controlled trials.
Chang CH, Liu CY, Chen SJ, Tsai HC. Chang CH, et al. Sci Rep. 2021 Nov 26;11(1):22996. doi: 10.1038/s41598-021-02040-5. Sci Rep. 2021. PMID: 34836972 Free PMC article.
This exploratory meta-analysis investigated the effectiveness of NMDA receptor enhancing agents for cognitive function. ...This exploratory meta-analysis showed a very small, positive, and significant effect on overall cognition function …
This exploratory meta-analysis investigated the effectiveness of NMDA receptor enhancing agents for cognitive function. …
Remote Collaborative Care With Off-Site Behavioral Health Care Managers: A Systematic Review of Clinical Trials.
Whitfield J, LePoire E, Stanczyk B, Ratzliff A, Cerimele JM. Whitfield J, et al. J Acad Consult Liaison Psychiatry. 2022 Jan-Feb;63(1):71-85. doi: 10.1016/j.jaclp.2021.07.012. Epub 2021 Aug 10. J Acad Consult Liaison Psychiatry. 2022. PMID: 34389509 Review.
The Collaborative Care Model (CoCM) is a team-based, highly-coordinated approach to treating common mental health conditions in primary care that has a robust evidence base. ...CONCLUSIONS: As the 9 studies included in our systematic r …
The Collaborative Care Model (CoCM) is a team-based, highly-coordinated approach to treating common mental health condi …
Association of Task-Shared Psychological Interventions With Depression Outcomes in Low- and Middle-Income Countries: A Systematic Review and Individual Patient Data Meta-analysis.
Karyotaki E, Araya R, Kessler RC, Waqas A, Bhana A, Rahman A, Matsuzaka CT, Miguel C, Lund C, Garman EC, Nakimuli-Mpungu E, Petersen I, Naslund JA, Schneider M, Sikander S, Jordans MJD, Abas M, Slade P, Walters S, Brugha TS, Furukawa TA, Amanvermez Y, Mello MF, Wainberg ML, Cuijpers P, Patel V. Karyotaki E, et al. JAMA Psychiatry. 2022 May 1;79(5):430-443. doi: 10.1001/jamapsychiatry.2022.0301. JAMA Psychiatry. 2022. PMID: 35319740 Free PMC article.
DATA SOURCES: Systematic literature searches in PubMed, Embase, PsycINFO, and Cochrane Library up to January 1, 2021. STUDY SELECTION: Randomized clinical trials (RCTs) of task-shared psychological interventions compared with control conditions for adults wit …
DATA SOURCES: Systematic literature searches in PubMed, Embase, PsycINFO, and Cochrane Library up to January 1, 2021. STUDY SELECTION: Ra …
Efficacy and tolerability of antipsychotic polypharmacy for schizophrenia spectrum disorders. A systematic review and meta-analysis of individual patient data.
Lochmann van Bennekom MWH, IntHout J, Gijsman HJ, Akdede BBK, Yağcıoğlu AEA, Barnes TRE, Galling B, Gueorguieva R, Kasper S, Kreinin A, Nielsen J, Nielsen RE, Remington G, Repo-Tiihonen E, Schmidt-Kraepelin C, Shafti SS, Xiao L, Correll CU, Verkes RJ. Lochmann van Bennekom MWH, et al. Schizophr Res. 2024 Oct;272:1-11. doi: 10.1016/j.schres.2024.07.035. Epub 2024 Aug 13. Schizophr Res. 2024. PMID: 39142215
DESIGN: We searched PubMed, EMBASE, and the Cochrane Central Register of Randomized Trials until September 1, 2022, for randomized controlled trials comparing APP with antipsychotic monotherapy. We estimated the effects with a one-stage approach for patient-level moderator …
DESIGN: We searched PubMed, EMBASE, and the Cochrane Central Register of Randomized Trials until September 1, 2022, for randomized controlle …
Efficacy and Safety of Selective Serotonin Reuptake Inhibitors, Serotonin-Norepinephrine Reuptake Inhibitors, and Placebo for Common Psychiatric Disorders Among Children and Adolescents: A Systematic Review and Meta-analysis.
Locher C, Koechlin H, Zion SR, Werner C, Pine DS, Kirsch I, Kessler RC, Kossowsky J. Locher C, et al. JAMA Psychiatry. 2017 Oct 1;74(10):1011-1020. doi: 10.1001/jamapsychiatry.2017.2432. JAMA Psychiatry. 2017. PMID: 28854296 Free PMC article.
STUDY SELECTION: Published and unpublished randomized clinical trials of SSRIs or SNRIs in youths with DD, AD, OCD, or PTSD were included. Trials using other antidepressants (eg, tricyclic antidepressants, monoamine oxidase inhibitors) were excluded. DATA EXT …
STUDY SELECTION: Published and unpublished randomized clinical trials of SSRIs or SNRIs in youths with DD, AD, OCD, or …
Effectiveness of pharmacological treatments for severe agitation in real-world emergency settings: protocol of individual-participant-data network meta-analysis.
Siafis S, Wu H, Nomura N, Schneider-Thoma J, Bighelli I, Lorenz C, Dib JE, Tharyan P, Calver LA, Isbister GK, Chan EWY, Knott JC, Yap CYL, Mantovani C, Martel ML, Barbic D, Honer WG, Hansen WP, Huf G, Alexander J, Raveendran NS, Coutinho ESF, Priller J, Adams CE, Salanti G, Leucht S. Siafis S, et al. Syst Rev. 2024 Aug 2;13(1):205. doi: 10.1186/s13643-024-02623-z. Syst Rev. 2024. PMID: 39095865 Free PMC article.
BACKGROUND: Severe psychomotor agitation and aggression often require immediate pharmacological intervention, but clear evidence-based recommendations for choosing among the multiple options are lacking. To address this gap, we plan a systematic review and individua …
BACKGROUND: Severe psychomotor agitation and aggression often require immediate pharmacological intervention, but clear evidence-based recom …
Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care.
Agarwal S, Chin WY, Vasudevan L, Henschke N, Tamrat T, Foss HS, Glenton C, Bergman H, Fønhus MS, Ratanaprayul N, Pandya S, Mehl GL, Lewin S. Agarwal S, et al. Cochrane Database Syst Rev. 2025 Apr 7;4(4):CD012925. doi: 10.1002/14651858.CD012925.pub2. Cochrane Database Syst Rev. 2025. PMID: 40193137 Free PMC article. Review.
SEARCH METHODS: Cochrane CENTRAL, MEDLINE, Embase, Ovid Population Information Online (POPLINE), K4Health and WHO Global Health Library (2000 to November 2022). SELECTION CRITERIA: Randomised and non-randomised trials in community/primary care settings. PARTI …
SEARCH METHODS: Cochrane CENTRAL, MEDLINE, Embase, Ovid Population Information Online (POPLINE), K4Health and WHO Global Health Libra …
Collaborative care for depression and anxiety problems.
Archer J, Bower P, Gilbody S, Lovell K, Richards D, Gask L, Dickens C, Coventry P. Archer J, et al. Cochrane Database Syst Rev. 2012 Oct 17;10(10):CD006525. doi: 10.1002/14651858.CD006525.pub2. Cochrane Database Syst Rev. 2012. PMID: 23076925 Free PMC article. Review.
BACKGROUND: Common mental health problems, such as depression and anxiety, are estimated to affect up to 15% of the UK population at any one time, and health care systems worldwide need to implement interventions to reduce the impact and burden of these condi …
BACKGROUND: Common mental health problems, such as depression and anxiety, are estimated to affect up to 15% of the UK population at …
12 results