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Effects of gonadotropin-releasing hormone antagonists on the expression of vascular endothelial growth factor and its receptors in a rat model of ovarian hyperstimulation syndrome.
Tong XM, Zhang SY, Song T, Xu WH, Lin XN, Shu J, Liu L. Tong XM, et al. Chin Med J (Engl). 2008 Dec 5;121(23):2434-9. Chin Med J (Engl). 2008. PMID: 19102964
Our aim was to investigate the effects of GnRHanta on vascular permeability and the expression of vascular endothelial growth factor (VEGF) and its receptors in a rat model of OHSS. ...Three ovarian stimulation protocols wer …
Our aim was to investigate the effects of GnRHanta on vascular permeability and the expression of vascular en
Expression of anti-Mullerian hormone protein during early follicular development in the primate ovary in vivo is influenced by suppression of gonadotropin secretion and inhibition of vascular endothelial growth factor.
Thomas FH, Telfer EE, Fraser HM. Thomas FH, et al. Endocrinology. 2007 May;148(5):2273-81. doi: 10.1210/en.2006-1501. Epub 2007 Feb 22. Endocrinology. 2007. PMID: 17317775
The aim of this study was to determine the pattern of AMH protein expression in the marmoset ovary and to investigate the effects of inhibition of gonadotropins or vascular endothelial growth factor (VEGF) activity on AMH expression
The aim of this study was to determine the pattern of AMH protein expression in the marmoset ovary and to investigate the effects
Expression of GnRH receptor in the canine corpus luteum, and luteal function following deslorelin acetate-induced puberty delay.
Kaya D, Gram A, Kowalewski MP, Schäfer-Somi S, Kuru M, Boos A, Aslan S. Kaya D, et al. Reprod Domest Anim. 2017 Dec;52(6):1104-1112. doi: 10.1111/rda.13038. Epub 2017 Sep 30. Reprod Domest Anim. 2017. PMID: 28963736
The goals of this study were as follows: (Experiment 1) to examine the basic capability of canine corpora lutea (CL) to respond to GnRH by assessing expression of gonadotropin-releasing hormone receptor (GnRH-R) in luteal samples collected throu …
The goals of this study were as follows: (Experiment 1) to examine the basic capability of canine corpora lutea (CL) to respond to GnRH by a …
Reducing the Risk of OHSS by GnRH Agonist Triggering.
Casper RF. Casper RF. J Clin Endocrinol Metab. 2015 Dec;100(12):4396-8. doi: 10.1210/jc.2015-3676. Epub 2015 Oct 29. J Clin Endocrinol Metab. 2015. PMID: 26513003
There is evidence that administration of GnRH agonist as the trigger for final follicular maturation, instead of the usual human chorionic gonadotropin trigger, will reduce the risk of OHSS by shortening the duration of luteal stimulation, lowering estrogen levels by induc …
There is evidence that administration of GnRH agonist as the trigger for final follicular maturation, instead of the usual human chorionic …
Targeted drug and gene delivery systems for lung cancer therapy.
Sundaram S, Trivedi R, Durairaj C, Ramesh R, Ambati BK, Kompella UB. Sundaram S, et al. Clin Cancer Res. 2009 Dec 1;15(23):7299-308. doi: 10.1158/1078-0432.CCR-09-1745. Epub 2009 Nov 17. Clin Cancer Res. 2009. PMID: 19920099 Free PMC article.
PURPOSE: To evaluate the efficacy of a novel docetaxel derivative of deslorelin, a luteinizing hormone-releasing hormone (LHRH) agonist, and its combination in vivo with RGD peptide conjugated nanoparticles encapsulating an antiangiogenic, anti-vascular
PURPOSE: To evaluate the efficacy of a novel docetaxel derivative of deslorelin, a luteinizing hormone-releasing hormone
Oestrogen and progesterone receptors in the marmoset endometrium: changes during the ovulatory cycle, early pregnancy and after inhibition of vascular endothelial growth factor, GnRH or ovariectomy.
Silvestri A, Fraser HM. Silvestri A, et al. Reproduction. 2007 Aug;134(2):341-53. doi: 10.1530/REP-06-0266. Reproduction. 2007. PMID: 17660243
These receptors were localised and semi-quantitatively analysed throughout the ovulatory cycle, weeks 2, 3 and 4 of pregnancy and after treatment with GnRH antagonist, vascular endothelial growth factor (VEGF) Trap or ovariectomy. ...E
These receptors were localised and semi-quantitatively analysed throughout the ovulatory cycle, weeks 2, 3 and 4 of pregnancy and aft …
Regulation of ovarian angiogenesis and apoptosis by GnRH-I analogs.
Parborell F, Irusta G, Rodríguez Celín A, Tesone M. Parborell F, et al. Mol Reprod Dev. 2008 Apr;75(4):623-31. doi: 10.1002/mrd.20806. Mol Reprod Dev. 2008. PMID: 17874466
We evaluated the direct in vivo effects of both the GnRH-agonist Leuprolide acetate (LA) and the GnRH-antagonist Antide (Ant) on the expression of VEGF-A and ANPT-1 and their receptors in ovarian follicles from prepubertal eCG-treated rats. We also exa …
We evaluated the direct in vivo effects of both the GnRH-agonist Leuprolide acetate (LA) and the GnRH-antagonist Antide (Ant) …
GnRH Agonist Triggering Modulates PEDF to VEGF Ratio Inversely to hCG in Granulosa Cells.
Miller I, Chuderland D, Ron-El R, Shalgi R, Ben-Ami I. Miller I, et al. J Clin Endocrinol Metab. 2015 Nov;100(11):E1428-36. doi: 10.1210/jc.2015-2312. Epub 2015 Aug 26. J Clin Endocrinol Metab. 2015. PMID: 26308290
CONTEXT: GnRH agonist (GnRH-a) triggering is associated with a reduced risk of ovarian hyperstimulation syndrome (OHSS) compared with human chorionic gonadotropin (hCG) in assisted reproduction technology cycles. We have shown that ovarian pigment epithelium derived fac
CONTEXT: GnRH agonist (GnRH-a) triggering is associated with a reduced risk of ovarian hyperstimulation syndrome (OHSS) compared with human …
Urinary gonadotrophins but not recombinant gonadotrophins reduce expression of VEGF120 and its receptors flt-1 and flk-1 in the mouse uterus during the peri-implantation period.
Sibug RM, de Koning J, Tijssen AM, de Ruiter MC, de Kloet ER, Helmerhorst FM. Sibug RM, et al. Hum Reprod. 2005 Mar;20(3):649-56. doi: 10.1093/humrep/deh648. Epub 2004 Dec 9. Hum Reprod. 2005. PMID: 15591083
METHODS: Adult female CD1 mice were treated as follows (a) urinary hFSH and urinary hCG, (b) recombinant hFSH and recombinant hLH and (c) saline. The effects of the gonadotrophins on the expression of vascular endothelial growth factor120 (VEG12 …
METHODS: Adult female CD1 mice were treated as follows (a) urinary hFSH and urinary hCG, (b) recombinant hFSH and recombinant hLH and (c) sa …
Thrombospondin-1 expression is increased during follicular atresia in the primate ovary.
Thomas FH, Wilson H, Silvestri A, Fraser HM. Thomas FH, et al. Endocrinology. 2008 Jan;149(1):185-92. doi: 10.1210/en.2007-0835. Epub 2007 Sep 20. Endocrinology. 2008. PMID: 17884943
The aim of this study was to determine the pattern of TSP-1 mRNA and protein expression as well as expression of its receptor CD36 in the marmoset ovary and to investigate the effects of inhibition of gonadotropins or VEGF activity on TSP-1 and CD36 …
The aim of this study was to determine the pattern of TSP-1 mRNA and protein expression as well as expression of its recept
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