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Inhaled gases as novel neuroprotective therapies in the postcardiac arrest period.
Magliocca A, Fries M. Magliocca A, et al. Curr Opin Crit Care. 2021 Jun 1;27(3):255-260. doi: 10.1097/MCC.0000000000000820. Curr Opin Crit Care. 2021. PMID: 33769417 Review.
Safety of both Xe and H2 after cardiac arrest has been reported in phase 1 clinical trials. A randomized phase 2 clinical trial showed the neuroprotective effects of Xe, combined with targeted temperature management. ...Ventilation …
Safety of both Xe and H2 after cardiac arrest has been reported in phase 1 clinical trials. A randomized
Randomized double-blind placebo-controlled trial of hydrogen inhalation for Parkinson's disease: a pilot study.
Yoritaka A, Kobayashi Y, Hayashi T, Saiki S, Hattori N. Yoritaka A, et al. Neurol Sci. 2021 Nov;42(11):4767-4770. doi: 10.1007/s10072-021-05489-4. Epub 2021 Jul 28. Neurol Sci. 2021. PMID: 34319514 Free PMC article. Clinical Trial.
A placebo-controlled, randomized, double-blind, parallel-group clinical pilot study was conducted to assess the efficacy of hydrogen gas inhalation in Japanese patients with PD on treatment with levodopa. ...RESULTS: Five participa …
A placebo-controlled, randomized, double-blind, parallel-group clinical pilot study was conducted to assess the …
Hydrogen, a Novel Therapeutic Molecule, Regulates Oxidative Stress, Inflammation, and Apoptosis.
Tian Y, Zhang Y, Wang Y, Chen Y, Fan W, Zhou J, Qiao J, Wei Y. Tian Y, et al. Front Physiol. 2021 Dec 20;12:789507. doi: 10.3389/fphys.2021.789507. eCollection 2021. Front Physiol. 2021. PMID: 34987419 Free PMC article. Review.
Molecular hydrogen (H(2)) is a colorless and odorless gas. Studies have shown that H(2) inhalation has the therapeutic effects in many animal studies and clinical trials, and its application is recommended in the novel coronavirus pneumon …
Molecular hydrogen (H(2)) is a colorless and odorless gas. Studies have shown that H(2) inhalation has the therapeutic …
New Perspectives for Mucolytic, Anti-inflammatory and Adjunctive Therapy with 1,8-Cineole in COPD and Asthma: Review on the New Therapeutic Approach.
Juergens LJ, Worth H, Juergens UR. Juergens LJ, et al. Adv Ther. 2020 May;37(5):1737-1753. doi: 10.1007/s12325-020-01279-0. Epub 2020 Mar 21. Adv Ther. 2020. PMID: 32200535 Free PMC article. Review.
In lymphocytes from healthy human donors 1,8-cineole inhibited TNFalpha, IL-1beta, IL-4 and IL-5 and demonstrated for the first time control of Th1/2-type inflammation. 1,8-Cineole at relevant plasma levels increased additively in vitro the efficacy of inhaled guide …
In lymphocytes from healthy human donors 1,8-cineole inhibited TNFalpha, IL-1beta, IL-4 and IL-5 and demonstrated for the first time control …
Co-administration of hydrogen and metformin exerts cardioprotective effects by inhibiting pyroptosis and fibrosis in diabetic cardiomyopathy.
Zou R, Nie C, Pan S, Wang B, Hong X, Xi S, Bai J, Yu M, Liu J, Yang W. Zou R, et al. Free Radic Biol Med. 2022 Apr;183:35-50. doi: 10.1016/j.freeradbiomed.2022.03.010. Epub 2022 Mar 15. Free Radic Biol Med. 2022. PMID: 35304269
In this study, we found that hydrogen improved cardiac dysfunction and abnormal morphological structure in streptozotocin-induced diabetic mice. ...In conclusion, our study demonstrated that hydrogen inhalation attenuates DCM by reducing …
In this study, we found that hydrogen improved cardiac dysfunction and abnormal morphological structure in streptozotoc …
Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial.
Tamura T, Hayashida K, Sano M, Onuki S, Suzuki M. Tamura T, et al. Trials. 2017 Oct 23;18(1):488. doi: 10.1186/s13063-017-2246-3. Trials. 2017. PMID: 29058596 Free PMC article. Clinical Trial.
BACKGROUND: Hydrogen gas inhalation (HI) improved survival and neurological outcomes in an animal model of post-cardiac arrest syndrome (PCAS). ...METHODS/DESIGN: The efficacy of inhaled HYdrogen on neurolog
BACKGROUND: Hydrogen gas inhalation (HI) improved survival and neurological outcomes in an animal model of po
Controlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis.
Zan R, Wang H, Cai W, Ni J, Luthringer-Feyerabend BJC, Wang W, Peng H, Ji W, Yan J, Xia J, Song Y, Zhang X. Zan R, et al. Bioact Mater. 2021 Aug 9;9:385-396. doi: 10.1016/j.bioactmat.2021.07.026. eCollection 2022 Mar. Bioact Mater. 2021. PMID: 34820578 Free PMC article.
Hydrogen has been used to suppress tumor growth with considerable efficacy. Inhalation of hydrogen gas and oral ingestion of hydrogen-rich saline are two common systemic routes of hydrogen administration. ...
Hydrogen has been used to suppress tumor growth with considerable efficacy. Inhalation of hydrogen gas and oral
Hydrogen peroxide vapor decontamination of N95 respirators for reuse.
Kenney PA, Chan BK, Kortright KE, Cintron M, Russi M, Epright J, Lee L, Balcezak TJ, Havill NL, Martinello RA. Kenney PA, et al. Infect Control Hosp Epidemiol. 2022 Jan;43(1):45-47. doi: 10.1017/ice.2021.48. Epub 2021 Feb 9. Infect Control Hosp Epidemiol. 2022. PMID: 33557979 Free PMC article.
Reprocessing of used N95 respirators may provide a higher filtration crisis alternative, but whether effective sterilization can be achieved for a virus without impairing respirator function remains unknown. We evaluated the viricidal efficacy of Bioquell vaporized hydr
Reprocessing of used N95 respirators may provide a higher filtration crisis alternative, but whether effective sterilization can be achieved …
Protective effects of hydrogen gas against spinal cord ischemia-reperfusion injury.
Kimura A, Suehiro K, Mukai A, Fujimoto Y, Funao T, Yamada T, Mori T. Kimura A, et al. J Thorac Cardiovasc Surg. 2022 Dec;164(6):e269-e283. doi: 10.1016/j.jtcvs.2021.04.077. Epub 2021 May 4. J Thorac Cardiovasc Surg. 2022. PMID: 34090694
METHODS: Male Sprague-Dawley rats were divided into the following 6 groups: sham, only spinal ischemia, 3% hydrogen gas (spinal ischemia + 3% hydrogen gas), 2% hydrogen gas (spinal ischemia + 2% hydrogen gas), 1% hydrogen
METHODS: Male Sprague-Dawley rats were divided into the following 6 groups: sham, only spinal ischemia, 3% hydrogen gas …
Inhalation of Molecular Hydrogen, a Rescue Treatment for Noise-Induced Hearing Loss.
Fransson AE, Videhult Pierre P, Risling M, Laurell GFE. Fransson AE, et al. Front Cell Neurosci. 2021 Jun 1;15:658662. doi: 10.3389/fncel.2021.658662. eCollection 2021. Front Cell Neurosci. 2021. PMID: 34140880 Free PMC article.
Thus, there is an urgent need to develop rescue treatment for patients with acute acoustic injuries. Hydrogen gas has antioxidant effects, rapid distribution, and distributes systemically after inhalation.The purpose of this study was to determine the protect …
Thus, there is an urgent need to develop rescue treatment for patients with acute acoustic injuries. Hydrogen gas has antioxidant eff …
84 results