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New Perspectives for Mucolytic, Anti-inflammatory and Adjunctive Therapy with 1,8-Cineole in COPD and Asthma: Review on the New Therapeutic Approach.
Juergens LJ, Worth H, Juergens UR. Juergens LJ, et al. Adv Ther. 2020 May;37(5):1737-1753. doi: 10.1007/s12325-020-01279-0. Epub 2020 Mar 21. Adv Ther. 2020. PMID: 32200535 Free PMC article. Review.
In lymphocytes from healthy human donors 1,8-cineole inhibited TNFalpha, IL-1beta, IL-4 and IL-5 and demonstrated for the first time control of Th1/2-type inflammation. 1,8-Cineole at relevant plasma levels increased additively in vitro the efficacy of inhaled guide …
In lymphocytes from healthy human donors 1,8-cineole inhibited TNFalpha, IL-1beta, IL-4 and IL-5 and demonstrated for the first time control …
Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial.
Tamura T, Hayashida K, Sano M, Onuki S, Suzuki M. Tamura T, et al. Trials. 2017 Oct 23;18(1):488. doi: 10.1186/s13063-017-2246-3. Trials. 2017. PMID: 29058596 Free PMC article. Clinical Trial.
BACKGROUND: Hydrogen gas inhalation (HI) improved survival and neurological outcomes in an animal model of post-cardiac arrest syndrome (PCAS). ...METHODS/DESIGN: The efficacy of inhaled HYdrogen on neurolog
BACKGROUND: Hydrogen gas inhalation (HI) improved survival and neurological outcomes in an animal model of po
Hydroxocobalamin in cyanide poisoning.
Thompson JP, Marrs TC. Thompson JP, et al. Clin Toxicol (Phila). 2012 Dec;50(10):875-85. doi: 10.3109/15563650.2012.742197. Epub 2012 Nov 19. Clin Toxicol (Phila). 2012. PMID: 23163594 Review.
Evidence that hydroxocobalamin is effective in poisoning due to hydrogen cyanide alone is lacking; extrapolation of efficacy from poisoning by ingested cyanide salts may not be valid. The rate of absorption may be greater with inhaled hydrogen cyanide …
Evidence that hydroxocobalamin is effective in poisoning due to hydrogen cyanide alone is lacking; extrapolation of efficacy f …
Emerging therapies for smoke inhalation injury: a review.
Mercel A, Tsihlis ND, Maile R, Kibbe MR. Mercel A, et al. J Transl Med. 2020 Mar 30;18(1):141. doi: 10.1186/s12967-020-02300-4. J Transl Med. 2020. PMID: 32228626 Free PMC article. Review.
MAIN BODY: A comprehensive literature search was performed using PubMed (1995-present) for therapies not approved by the U.S. Food and Drug Administration (FDA) for smoke inhalation injury with or without concurrent burn injury. Therapies were divided based o …
MAIN BODY: A comprehensive literature search was performed using PubMed (1995-present) for therapies not approved by the U.S. Food an …
Safety and efficacy of Biomin()DC-C as a zootechnical feed additive for weaned piglets.
EFSA Panel on Additives and Products or Substances used in Animal Feed (EFSA FEEDAP Panel), Bampidis V, Azimonti G, Bastos ML, Christensen H, Dusemund B, Kouba M, Kos Durjava M, López-Alonso M, López Puente S, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F, Sanz Y, Villa RE, Woutersen R, Chesson A, Gropp J, Martelli G, Renshaw D, López-Gálvez G, Mantovani A. EFSA Panel on Additives and Products or Substances used in Animal Feed (EFSA FEEDAP Panel), et al. EFSA J. 2019 Apr 16;17(4):e05688. doi: 10.2903/j.efsa.2019.5688. eCollection 2019 Apr. EFSA J. 2019. PMID: 32626295 Free PMC article.
The FEEDAP Panel considered that exposure to users by inhalation is unlikely; in the absence of data, the Panel cannot conclude on the effects of Biomin() DC-C on skin and eyes. The use of the additive in animal production is not expected to pose a risk for the terrestrial …
The FEEDAP Panel considered that exposure to users by inhalation is unlikely; in the absence of data, the Panel cannot conclude on th …
Molecular hydrogen as a novel antioxidant: overview of the advantages of hydrogen for medical applications.
Ohta S. Ohta S. Methods Enzymol. 2015;555:289-317. doi: 10.1016/bs.mie.2014.11.038. Epub 2015 Jan 21. Methods Enzymol. 2015. PMID: 25747486 Review.
Molecular hydrogen (H2) was believed to be inert and nonfunctional in mammalian cells. ...Owing to its great efficacy and lack of adverse effects, H2 has potential for clinical applications for many diseases....
Molecular hydrogen (H2) was believed to be inert and nonfunctional in mammalian cells. ...Owing to its great efficacy and lack …
Modest and variable efficacy of pre-exposure hydroxocobalamin and dicobalt edetate in a porcine model of acute cyanide salt poisoning.
Thompson A, Dunn M, Jefferson RD, Dissanayake K, Reed F, Gregson R, Greenhalgh S, Clutton RE, Blain PG, Thomas SH, Eddleston M. Thompson A, et al. Clin Toxicol (Phila). 2020 Mar;58(3):190-200. doi: 10.1080/15563650.2019.1628969. Epub 2019 Aug 7. Clin Toxicol (Phila). 2020. PMID: 31389254 Free PMC article.
Background: Dicobalt edetate and hydroxocobalamin are widely used to treat hydrogen cyanide poisoning. However, comparative and quantitative efficacy data are lacking. ...In clinical poisoning scenarios, with delayed administration, the antidotes are l …
Background: Dicobalt edetate and hydroxocobalamin are widely used to treat hydrogen cyanide poisoning. However, comparative and quant …
Gaseous therapeutics in acute lung injury.
Ryter SW, Choi AM. Ryter SW, et al. Compr Physiol. 2011 Jan;1(1):105-21. doi: 10.1002/cphy.c090003. Compr Physiol. 2011. PMID: 23737166 Review.
H2S, a third potential therapeutic gas, can induce hypometabolic states in mice and can confer both pro- and anti-inflammatory effects in rodent models of ALI and sepsis. Clinical studies have shown variable results for the efficacy of iNO in lung transplanta …
H2S, a third potential therapeutic gas, can induce hypometabolic states in mice and can confer both pro- and anti-inflammatory effects in ro …
Oral Administration of Si-Based Agent Attenuates Oxidative Stress and Ischemia-Reperfusion Injury in a Rat Model: A Novel Hydrogen Administration Method.
Kawamura M, Imamura R, Kobayashi Y, Taniguchi A, Nakazawa S, Kato T, Namba-Hamano T, Abe T, Uemura M, Kobayashi H, Nonomura N. Kawamura M, et al. Front Med (Lausanne). 2020 Mar 20;7:95. doi: 10.3389/fmed.2020.00095. eCollection 2020. Front Med (Lausanne). 2020. PMID: 32266279 Free PMC article.
Organ ischemia-reperfusion injury (IRI), which is unavoidable in kidney transplantation, induces the formation of reactive oxygen species and causes organ damage. Although the efficacy of molecular hydrogen (H(2)) in IRI has been reported, oral intake of H(2) …
Organ ischemia-reperfusion injury (IRI), which is unavoidable in kidney transplantation, induces the formation of reactive oxygen spe …
Protective effects of hydrogen gas in a rat model of branch retinal vein occlusion via decreasing VEGF-alpha expression.
Long P, Yan W, He M, Zhang Q, Wang Z, Li M, Xue J, Chen T, An J, Zhang Z. Long P, et al. BMC Ophthalmol. 2019 May 16;19(1):112. doi: 10.1186/s12886-019-1105-2. BMC Ophthalmol. 2019. PMID: 31096936 Free PMC article.
This study was designed to evaluate the efficacy of hydrogen gas on the BRVO rat model. ...Rats in the H group inhaled hydrogen gas for 8 h every day up to 30 d post-occlusion. ...
This study was designed to evaluate the efficacy of hydrogen gas on the BRVO rat model. ...Rats in the H group inhal
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