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CTLA-4: new insights into its biological function and use in tumor immunotherapy.
Egen JG, Kuhns MS, Allison JP. Egen JG, et al. Nat Immunol. 2002 Jul;3(7):611-8. doi: 10.1038/ni0702-611. Nat Immunol. 2002. PMID: 12087419 Review.
IgE⁺ memory B cells and plasma cells generated through a germinal-center pathway.
Talay O, Yan D, Brightbill HD, Straney EE, Zhou M, Ladi E, Lee WP, Egen JG, Austin CD, Xu M, Wu LC. Talay O, et al. Among authors: egen jg. Nat Immunol. 2012 Feb 26;13(4):396-404. doi: 10.1038/ni.2256. Nat Immunol. 2012. PMID: 22366892
Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung.
Lafkas D, Shelton A, Chiu C, de Leon Boenig G, Chen Y, Stawicki SS, Siltanen C, Reichelt M, Zhou M, Wu X, Eastham-Anderson J, Moore H, Roose-Girma M, Chinn Y, Hang JQ, Warming S, Egen J, Lee WP, Austin C, Wu Y, Payandeh J, Lowe JB, Siebel CW. Lafkas D, et al. Nature. 2015 Dec 3;528(7580):127-31. doi: 10.1038/nature15715. Epub 2015 Nov 18. Nature. 2015. PMID: 26580007
Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis.
Ishii M, Egen JG, Klauschen F, Meier-Schellersheim M, Saeki Y, Vacher J, Proia RL, Germain RN. Ishii M, et al. Among authors: egen jg. Nature. 2009 Mar 26;458(7237):524-8. doi: 10.1038/nature07713. Epub 2009 Feb 8. Nature. 2009. PMID: 19204730 Free PMC article.
B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapse.
Pentcheva-Hoang T, Egen JG, Wojnoonski K, Allison JP. Pentcheva-Hoang T, et al. Among authors: egen jg. Immunity. 2004 Sep;21(3):401-13. doi: 10.1016/j.immuni.2004.06.017. Immunity. 2004. PMID: 15357951
Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength.
Egen JG, Allison JP. Egen JG, et al. Immunity. 2002 Jan;16(1):23-35. doi: 10.1016/s1074-7613(01)00259-x. Immunity. 2002. PMID: 11825563
CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy.
Chambers CA, Kuhns MS, Egen JG, Allison JP. Chambers CA, et al. Among authors: egen jg. Annu Rev Immunol. 2001;19:565-94. doi: 10.1146/annurev.immunol.19.1.565. Annu Rev Immunol. 2001. PMID: 11244047 Review.
LILRB1 Blockade Enhances Bispecific T Cell Engager Antibody-Induced Tumor Cell Killing by Effector CD8+ T Cells.
Kim A, Han CJ, Driver I, Olow A, Sewell AK, Zhang Z, Ouyang W, Egen JG, Yu X. Kim A, et al. Among authors: egen jg. J Immunol. 2019 Aug 15;203(4):1076-1087. doi: 10.4049/jimmunol.1801472. Epub 2019 Jun 28. J Immunol. 2019. PMID: 31253728 Free PMC article.
Pathogen-related differences in the abundance of presented antigen are reflected in CD4+ T cell dynamic behavior and effector function in the lung.
Torabi-Parizi P, Vrisekoop N, Kastenmuller W, Gerner MY, Egen JG, Germain RN. Torabi-Parizi P, et al. Among authors: egen jg. J Immunol. 2014 Feb 15;192(4):1651-1660. doi: 10.4049/jimmunol.1301743. Epub 2014 Jan 15. J Immunol. 2014. PMID: 24431231 Free PMC article.
Highways, byways and breadcrumbs: directing lymphocyte traffic in the lymph node.
Bajénoff M, Egen JG, Qi H, Huang AY, Castellino F, Germain RN. Bajénoff M, et al. Among authors: egen jg. Trends Immunol. 2007 Aug;28(8):346-52. doi: 10.1016/ Epub 2007 Jul 10. Trends Immunol. 2007. PMID: 17625969 Review.
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