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42 results
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B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapse.
Pentcheva-Hoang T, Egen JG, Wojnoonski K, Allison JP. Pentcheva-Hoang T, et al. Among authors: egen jg. Immunity. 2004 Sep;21(3):401-13. doi: 10.1016/j.immuni.2004.06.017. Immunity. 2004. PMID: 15357951
Peripheral prepositioning and local CXCL9 chemokine-mediated guidance orchestrate rapid memory CD8+ T cell responses in the lymph node.
Kastenmüller W, Brandes M, Wang Z, Herz J, Egen JG, Germain RN. Kastenmüller W, et al. Among authors: egen jg. Immunity. 2013 Mar 21;38(3):502-13. doi: 10.1016/j.immuni.2012.11.012. Epub 2013 Jan 24. Immunity. 2013. PMID: 23352234 Free PMC article.
Tuning of antigen sensitivity by T cell receptor-dependent negative feedback controls T cell effector function in inflamed tissues.
Honda T, Egen JG, Lämmermann T, Kastenmüller W, Torabi-Parizi P, Germain RN. Honda T, et al. Among authors: egen jg. Immunity. 2014 Feb 20;40(2):235-247. doi: 10.1016/j.immuni.2013.11.017. Epub 2014 Jan 16. Immunity. 2014. PMID: 24440150 Free PMC article.
Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas.
Egen JG, Rothfuchs AG, Feng CG, Winter N, Sher A, Germain RN. Egen JG, et al. Immunity. 2008 Feb;28(2):271-84. doi: 10.1016/j.immuni.2007.12.010. Epub 2008 Feb 7. Immunity. 2008. PMID: 18261937 Free PMC article.
Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes.
Bajénoff M, Egen JG, Koo LY, Laugier JP, Brau F, Glaichenhaus N, Germain RN. Bajénoff M, et al. Among authors: egen jg. Immunity. 2006 Dec;25(6):989-1001. doi: 10.1016/j.immuni.2006.10.011. Epub 2006 Nov 16. Immunity. 2006. PMID: 17112751 Free PMC article.
Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength.
Egen JG, Allison JP. Egen JG, et al. Immunity. 2002 Jan;16(1):23-35. doi: 10.1016/s1074-7613(01)00259-x. Immunity. 2002. PMID: 11825563
CTLA-4: new insights into its biological function and use in tumor immunotherapy.
Egen JG, Kuhns MS, Allison JP. Egen JG, et al. Nat Immunol. 2002 Jul;3(7):611-8. doi: 10.1038/ni0702-611. Nat Immunol. 2002. PMID: 12087419 Review.
Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas.
Egen JG, Rothfuchs AG, Feng CG, Horwitz MA, Sher A, Germain RN. Egen JG, et al. Immunity. 2011 May 27;34(5):807-19. doi: 10.1016/j.immuni.2011.03.022. Epub 2011 May 19. Immunity. 2011. PMID: 21596592 Free PMC article.
CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy.
Chambers CA, Kuhns MS, Egen JG, Allison JP. Chambers CA, et al. Among authors: egen jg. Annu Rev Immunol. 2001;19:565-94. doi: 10.1146/annurev.immunol.19.1.565. Annu Rev Immunol. 2001. PMID: 11244047 Review.
Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung.
Lafkas D, Shelton A, Chiu C, de Leon Boenig G, Chen Y, Stawicki SS, Siltanen C, Reichelt M, Zhou M, Wu X, Eastham-Anderson J, Moore H, Roose-Girma M, Chinn Y, Hang JQ, Warming S, Egen J, Lee WP, Austin C, Wu Y, Payandeh J, Lowe JB, Siebel CW. Lafkas D, et al. Nature. 2015 Dec 3;528(7580):127-31. doi: 10.1038/nature15715. Epub 2015 Nov 18. Nature. 2015. PMID: 26580007
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